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Perio II – Immunology & Microbial Pathogenesis in Periodontal Disease 2025/2026 | 150+ A+ Questions & Answers on Antibodies, Innate vs Adaptive Immunity, Biofilm, Bone Loss & Host Response

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This intensive study guide offers 150+ graded and verified exam questions with answers for Perio II Test 1 (2025/2026), with a focus on the immunologic and microbial mechanisms involved in periodontal disease. Topics include antibody types (IgM, IgG, IgA, IgE), innate vs adaptive immune responses, antigen presentation, cytokine function (IL-1, IL-8, TNF), inflammatory mediators (histamine, prostaglandins), biofilm stages and composition, bacterial virulence factors, periodontal disease models, antimicrobial agents, and host-microbe interactions. Essential for students in Dental Hygiene, Periodontics, Oral Immunology, and Microbiology preparing for advanced-level exams or clinical case assessments. Keywords: IgG, IgM, IgA, adaptive immunity, innate immunity, B cells, T cells, neutrophils, macrophages, cytokines, interleukins, CD4, CD8, MHC class I, MHC class II, biofilm formation, plaque maturity, gingivitis, periodontitis, P. gingivalis, bacterial endotoxins, complement system, antibody structure, microbial virulence, alveolar bone loss, antimicrobial rinses, chlorhexidine, periostat, host response, periodontal pocket, inflammatory mediators, bone resorption

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Subido en
21 de julio de 2025
Número de páginas
23
Escrito en
2024/2025
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Examen
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Perio II: Test 1 2025/2026 Exam
Questions and Answers 100%
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blood - 🧠 ANSWER ✔✔mature lymphocytes are found where?


tissue - 🧠 ANSWER ✔✔mature dendritic cells are found where?


antibodies - 🧠 ANSWER ✔✔Extracellular pathogens are eliminated chiefly by

______________


T cells, macrophages - 🧠 ANSWER ✔✔intracellular pathogens require

__________ and _____________ for elimination.


cell-mediated immunity - 🧠 ANSWER ✔✔The function of T cells is sometimes

referred to as _________________


Antigen presenting cells - 🧠 ANSWER ✔✔__________________, such as

dendritic cells in the skin and macrophages are critical in initiating the activation of

B and T cells.


COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
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,neutrophils - 🧠 ANSWER ✔✔make up approximately 60% of all white blood cells


neutrophils - 🧠 ANSWER ✔✔most active phagocytic cells in the body


neutrophils - 🧠 ANSWER ✔✔serve as the primary effector cell in inflammation.


eosinophils - 🧠 ANSWER ✔✔destroy parasites and are a major component of

allergic reactions.


basophils - 🧠 ANSWER ✔✔role is unclear although it is known that they release

many of the chemicals involved in the inflammatory process.


monocytes - 🧠 ANSWER ✔✔extremely phagocytic. Those that have left the blood

stream and settled in the tissues are called macrophages.


macrophages - 🧠 ANSWER ✔✔monocytes that have left the blood stream and

settled in the tissues are called _______________


B lymphocytes - 🧠 ANSWER ✔✔Antibodies, are the antigen-specific proteins

produced by ________________ in response to contact with antigen.


antibodies - 🧠 ANSWER ✔✔_________________ circulate in the blood and

lymph as plasma components



COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
PRIVACY STATEMENT. ALL RIGHTS RESERVED

, light, heavy - 🧠 ANSWER ✔✔antibodies are made up of what two chains?


2, 2 - 🧠 ANSWER ✔✔In the basic immunoglobulin, there are __________ heavy

and _________ light chains linked together by intermolecular bonds.


antigen - 🧠 ANSWER ✔✔The primary function of all antibodies is to bind to an

______________.


agglutination - 🧠 ANSWER ✔✔clumping together


phagocytic cells - 🧠 ANSWER ✔✔If bacteria are coated with antibodies, this can

enhance the likelihood that they will be engulfed by ___________________


activate compliment & lytic - 🧠 ANSWER ✔✔Antibodies can also

____________________ and initiate a _______________ reaction that destroys

the cell to which the antibody is bound


IgM - 🧠 ANSWER ✔✔This is the predominant antibody early in an immune

response.


IgM - 🧠 ANSWER ✔✔It has ten potential antigen-binding sites and because of this

it is the most efficient antibody at agglutinating bacteria and activating

complement.


COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
PRIVACY STATEMENT. ALL RIGHTS RESERVED
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