,Chapter 01: Introduction to Pathophysiology
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Test Bank
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MULTIPLE CHOICE z
1. Which of the following would be the most likely cause of an iatrogenic disease?
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a. An inherited disorderz z
b. A combination of specific etiological factors
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c. An unwanted effect of a prescribed drug
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d. Prolonged exposure to toxic chemicals in the environment z z z z z z z
ANS: C z REF: 6 zz
2. The manifestations of a disease are best defined as the:
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a. subjective feelings of discomfort during a chronic illness.
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b. signs and symptoms of a disease.
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c. factors that precipitate an acute episode of a chronic illness.
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d. early indicators of the prodromal stage of infection.
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ANS: B z REF: 6 zz
3. The best definition of the term prognosis is the:
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a. precipitating factors causing an acute episode. z z z z z
b. number of remissions to be expected during the course of a chronic illness.
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c. predicted outcome or likelihood of recovery from a specific disease.
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d. exacerbations occurring during chronic illness. z z z z
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ANS: C z REF: 7 zz
4. Which of the following is considered a systemic sign of disease?
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a. Swelling of the knee z z z
b. Fever
c. Pain in the neck z z z
d. Red rash on the face z z z z
ANS: B z REF: 6 zz
5. Etiology is defined as the study of the:
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a. causes of a disease. z z z
b. course of a disease. z z z
c. expected complications of a disease. z z z z
d. manifestations of a disease. z z z
ANS: A z REF: 5 zz
6. A type of cellular adaptation in which there is a decrease in cell size is referred to as:
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a. hypertrophy.
b. metaplasia.
c. anaplasia.
d. atrophy.
ANS: D z REF: 8 zz
, 7. A change in a tissue marked by cells that vary in size and shape and show increased mitotic figu
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res would be called:
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a. metaplasia.
b. atrophy.
c. dysplasia.
d. hypertrophy.
ANS: C z REF: 8 zz
8. A deficit of oxygen in the cells usually due to respiratory or circulatory problems is called:
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a. apoptosis.
b. ischemia.
c. hypertrophy.
d. necrosis.
ANS: B z REF: 9 zz
9. When a group of cells in the body dies, the change is called:
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a. ischemia.
b. gangrene.
c. hypoxia.
d. necrosis.
ANS: D z REF: 10 zz
10. Rigorous weight lifting/body building regimens may result in the skeletal muscle cells
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undergoing: z
a. hypertrophy.
b. dysplasia.
c. atrophy.
d. regeneration.
ANS: A z REF: 8 zz
11. The term cancer refers to:
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a. dysplasia.
b. hyperplasia.
c. metaplasia.
d. malignant neoplasm. z
ANS: D z REF: 9 zz
12. To which of the following does the term apoptosis refer?
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a. Increased rate of mitosis by certain cells z z z z z z
b. Ischemic damage to cells z z z
c. Liquefaction of necrotic tissue z z z
d. Preprogrammed cell self-destruction z z
ANS: D z REF: 9 zz
13. Which of the following statements is TRUE?
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a. Alteration of DNA does not change cell function. z z z z z z z