What drug would the nurse expect to be administered as the antidote for the irreversible
indirect-acting cholinergic agonists?
A) Donepezil
B) Pyridostigmine
C) Pralidoxime
D) Edrophonium C) Pralidoxime
What is the duration of action the nurse would expect following administration of bethanechol?
A) 30-60 min
B) 6-8 hr
C) 2-4 hr
D) 1-6 hr D) 1-6 hr
When reviewing cholinergic agonists, the nurse learns that there are direct acting and indirect
acting cholinergic agonists. What is the agent acts directly or indirectly on?
A) Nerve impulse transmission
B) Acetylcholine potency
C) Acetylcholine production
D) Acetylcholine receptor sites D) Acetylcholine receptor sites
Which indirect-acting cholinergic agonist has the shortest duration of action?
A) Neostigmine
B) Namzaric
C) Pyridostigmine
D) Edrophonium D) Edrophonium
,Why are indirect acting cholinergic agonists used for treatment of myasthenia gravis but direct
acting agents are ineffective?
A) Indirect acting cholinergic agents reduce production of acetylcholinesterase
B) Direct acting cholinergic agents allow acetylcholine to accumulate
C) Indirect acting cholinergic agents can cross the BBB
D) Direct acting cholinergic agents have very short durations of action B) Direct acting
cholinergic agents allow acetylcholine to accumulate
The pregnant woman with myasthenia gravis has been taken off of all indirect-acting
cholinergic agents normally to treat her condition. The woman asks the nurse, "What would
happen if I took my medicine for myasthenia gravis anyway? What is the nurse's best
explanation for why the drug is contraindicated during pregnancy?
A) Taking indirect-acting cholinergic agents while pregnant could result in a uterine rupture
B) Taking your indirect-acting cholinergic agent could stimulate labor
C) Taking your indirect-acting agent could cause birth defects
D) Taking your indirect-acting cholinergic agent could cause overstimulation of your heart B)
Taking your indirect-acting cholinergic agent could stimulate labor
SATA. The nurse is caring for an older adult pt who has been prescribed Donepezil to treat
Alzheimer's disease. The nurse should question the pt's concurrent use of what medications?
A) Theophylline
B) Propranolol
C) Furosemide
D) Acetaminophen
E) Ibuprofen A) Theophylline
E) Ibuprofen
,Select all that apply: What adverse effects might a nurse assess in a pt receiving bethanechol?
A) Dehydration
B) Diarrhea
C) Pallor
D) Tachycardia
E) Diaphoresis A) Dehydration
B) Diarrhea
E) Diaphoresis
SATA. What should the nurse include when teaching the family of a pt with Alzheimer's about
the possible adverse effects associated with the prescribed Donepezil?
A) Constipation
B) Muscle cramps
C) Insomnia
D) Rash
E) HTN B) Muscle cramps
C) Insomnia
D) Rash
Select all that apply: The nurse, transcribing an order for a direct acting cholinergic agent,
would consider what conditions to be a contraindication to its use?
A) Asthma
B) Pregnancy
C) Peptic ulcer disease
D) Blader obstruction
E) Bradycardia A) Asthma
, C) Peptic ulcer disease
D) Blader obstruction
E) Bradycardia
The nurse is caring for a pt who has a long-standing diagnosis of myasthenia gravis and who
takes Pyridostigmine. What statement by the pt should the nurse prioritize for the follow-up?
A) I just don't seem to have much of an appetite these days
B) I'm drinking lots, but sometimes I just can't quench my thirst
C) I'm feeling so much weaker than I usually do
D) I'm worried that I'm getting worse, not better C) I'm feeling so much weaker than I
usually do
A male pt has been diagnosed with dementia and the nurse is teaching the pt and his wife
about his new prescription for Donepezil. What should the nurse teach the pt and his wife?
A) Diagnostic imaging in a few months will determine whether Donepezil is beneficial
B) Your husband will need a drug holiday in which all his other medications are temporarily
withheld, near the beginning of therapy
C) This won't cure your husband's dementia, but it can slow the progression significantly
D) This drug has benefits for many pts with Alzheimer's, but these are often not evident for 4-6
months C) This won't cure your husband's dementia, but it can slow the progression
significantly
A pt with progressive muscle weakness is undergoing diagnostic testing for myasthenia gravis.
Neostigmine 0.022 mg/kg has been prescribed and the pt weighs 144.8 lb. How much
Neostigmine should the nurse administer? Provide answer to two decimal places. 1.45 mg
When describing the functions of the ANS, which of the following would the instructor include?
A) Maintenance of balance and posture