TEST BANK
$t
Genetics and Genomics in Nursing and Health Care
$t $t $t $t $t $t $t
by Theresa A. Beery, M. Linda Workman
$t $t $t $t $t $t
First Edition
$t
FULL TEST BANK!!! $t $t
NURSINGBYTES
, Chapter 1: DNA Structure and Function
$t $t $t $t $t
Multiple Choice
Identify the choice that best completes the statement or answers the question.
A. 1. In which body or cell area are most genes in humans located?
A. Nucleus
B. Mitochondrion
C. Cytoplasm
D. Plasma membrane
A. 2. Which condition or statement exemplifies the concept of genomics rather than genetics?
A. The gene for insulin is located on chromosome 11 in all people.
B. Expression of any single gene is dependent on inheriting two alleles.
C. Sex-linked recessive disorders affect males more often than females.
D. One allele for each gene is inherited from the mother, and one is inherited from the
father.
A. 3. What is the purpose of phosphorous in a DNA strand?
A. Linking the nucleotides into a strand
B. Holding complementary strands together
C. Ensuring that a purine is always paired with a pyrimidine
D. Preventing the separation of double-stranded DNA into single-stranded DNA
A. 4. What is the term used to define alternative forms of a gene that may result in different expression
of the trait coded for by that gene?
A. Alleles
B. Bases
C. Centromeres
D. Diploids
D. 5. What percentage of bases in a stretch of double-stranded DNA that contains 30% guanine (G)
bases would be adenine (A)?
A. 70%
B. 60%
C. 30%
D. 20%
C. 6. What is the term used to describe the organized picture of the paired chromosomes within a cell
used to determine whether chromosome numbers, structures, and banding patterns are normal?
A. Pedigree
B. Phenotype
C. Karyotype
D. Autotype
D. 7. What would be the sequence of DNA that is complementary to a DNA section with the base
sequence of GGTCAATCCTTAG?
A. GATTCCTAACTGG
B. TTGACCGAAGGCT
C. AACTGGCTTCCGA
D. CCAGTTAGGAATC
NURSINGBYTES
,$ t $ t B. 8. $ t Which $tof $tthese $tcomplementary $tbase $tpairs $tform $tthe $tstrongest $tor $t“tightest” $tassociation?
A. Adenine $tand $tthymine
B. Cytosine $tand $tguanine
C. Guanine $tand $tthymine
D. Cytosine $tand $tadenine
$ t $ t A 9. $ t What $tactivity $toccurs $tduring $tM $tphase $tof $tthe $tcell $tcycle?
A. The $tcell $tundergoes $tcytokinesis.
B. Activity $tstops, $tand $tthe $tcell $t“sleeps.”
C. All $tDNA $tis $tcompletely $treplicated.
D. The $tcell $tgreatly $tincreases $tprotein $tsynthesis.
$ t $ t B. $ t $ t 10. $ t Which $tchromosome $tnumber $trepresents $tthe $teuploid $tstate $tfor $tnormal $thuman $tsomatic $tcells?
A. 44
B. 46
C. 47
D. 48
$ t $ t A. $ t 11. $ t How $tdoes $tthe $tproteome $tdiffer $tfrom $tthe $tgenome?
A. The $tproteome $tchanges $tin $tresponse $tto $tintracellular $tand $textracellular $tsignals.
B. The $tgenome $tchanges $tin $tresponse $tto $tintracellular $tand $textracellular $tsignals.
C. The $tproteome $tis $tstable $tin $tsomatic $tcells $tand $tunstable $tin $tgerm $tcells,
$t whereas $tthe $tgenome $tis $tstable $tin $tboth $tsomatic $tcells $tand $tgerm $tcells.
D. The $tgenome $tis $tstable $tin $tsomatic $tcells $tand $tunstable $tin $tgerm $tcells, $twhereas
the $tproteome $tis $tstable $tin $tboth $tsomatic $tcells $tand $tgerm $tcells.
$t
$ t $ t C. $ t $ t 12. $ t What $tis $tthe $tmost $toutstanding $tfeature $tof $ta $tmature $thaploid $tcell?
A. It $tis $tusually $thomozygous.
B. The $tsex $tchromosomes $tare $tmissing.
C. Only $tone $tchromosome $tof $teach $tpair $tis $tpresent.
D. DNA $tsynthesis $toccurs $tafter $tmitosis $tinstead $tof $tbefore.
$ t $ t D. $ t $ t 13. $ t At $twhat $tphase $tof $tthe $tcell $tcycle $tare $tchromosomes $tvisible $tas $tseparate $tstructures?
A. G1
B. G2
C. S
D. M
$ t $ t B. $ t 14. $ t Which $tstatement $tabout $tthe $tcell $tcycle $tphase $tof $tG0 $ t is $ttrue?
A. Hyperplastic $tgrowth $tin $tplace $tof $thypertrophic $tgrowth
B. Performance $tof $tspecific $tdifferentiated $tfunctions
C. Initiation $tand $tcompletion $tof $tnucleokinesis
D. Replication $tof $tDNA
$ t $ t B. $ t 15. $ t What $tis $tthe $tresult $tof $tnormal $tDNA $treplication?
A. Formation $tof $ttwo $tnew $tdaughter $tcells
B. Formation $tof $ttwo $tidentical $tsets $tof $tDNA
C. Disappearance $tof $tthe $toriginal $tparent $tcell
D. Activation $tand $tattachment $tof $tspindle $tfibers
NURSINGBYTES
, $ t $ t A. $ t 16. $ t Which $tstatement $tregarding $tchromosome $tstructure $tor $tfunction $tis $ttrue?
A. The $tchromatids $tof $tany $tsingle $tchromosome $tare $tknown $tas $t“sister $tchromatids.”
B. The $tgenes $tlocated $ton $tthe $ttelomeres $tof $tchromosomes $tare $tidentical $tto $tthe
$t genes $tin $tthe $tcentromeres.
C. Immediately $tbefore $tthe $tmitosis $tphase $tof $tcell $tdivision, $tthe $tchromosomes $tof
all $tsomatic $tcells $tare $thaploid.
$t
D. A $tspecific $tgene $tallele $ton $tone $tchromosome $thas $ta $tcomplementary $tallele $ton $tthe
$tother $tchromosome $tof $ta $tpair.
$ t $ t C. $ t $ t 17. $ t Why $tdoes $ta $tperson $twith $tnormal $tchromosomes $tonly $thave $ttwo $talleles $tfor $tany $tsingle $tgene
$t trait?
A. A $tminimum $tof $ttwo $talleles $tis $trequired $tfor $tthe $texpression $tof $tmonogenic $ttraits.
B. When $ta $tdominant $tallele $tis $tpaired $twith $ta $trecessive $tallele, $tonly $tthe $tdominant
$t allele $tis $texpressed, $tand $tthe $trecessive $tallele $tis $tsilent.
C. One $tallele $tfor $tthe $tmonogenic $ttrait $tis $ton $tthe $tpaternally $tderived $tchromosome,
and $tthe $tother $tallele $tis $ton $tthe $tmaternally $tderived $tchromosome.
$t
D. Expression $tof $tmore $tthan $ttwo $talleles $tof $tany $tsingle-gene $ttrait $tresults $tin
$t enhanced $texpression $tof $trecessive $talleles $tand $tsuppressed $texpression $tof
$t dominant $talleles.
$ t $ t C 18. Under $twhat $tnormal $tcondition $tare $tgenotype $tand $tphenotype $talways $tthe $tsame?
$ t
A. Euploidy $tof $talleles
B. Aneuploidy $tof $talleles
C. Homozygosity $tof $talleles
D. Heterozygosity $tof $talleles
$t $ t D. $ t 19. $ t What $twould $tbe $tthe $texpected $tresult $tof $ta $tdrug $tthat $taffected $ta $tparticular $ttissue $tby
causing $tnew $tDNA $tto $tform $twith $tcovalent $tbonds $tinstead $tof $thydrogen $tbonds?
$t
A. None $tof $tthe $tcells $tin $tthe $taffected $ttissue $twould $tbe $table $tto $tleave $tG0 $ t and $tenter
$t the $tcell $tcycle.
B. Replication $tof $tDNA $twould $tresult $tin $tidentical $tDNA $tstrands $tinstead
of $tcomplementary $tstrands.
$t
C. Mitosis $tof $tcells $tin $tthe $ttissue $twould $tresult $tin $tthe $tproduction $tof $tthree $tnew
daughter $tcells $tinstead $tof $tjust $ttwo.
$t
D. The $tnew $tcells $tthat $tformed $twithin $tthis $ttissue $twould $tnot $tbe $table $tto $tcomplete $tthe
$t next $tround $tof $tmitosis $tsuccessfully.
$ t $ t B. $ t 20. $ t How $tdoes $tthe $tDNA $tenzyme $ttopoisomerase $tcontribute $tto $tDNA $treplication?
A. Unwinds $tthe $tdouble $thelix $tand $tseparates $tthe $tdouble-stranded $tDNA
B. Creates $ta $t“nick” $tin $tthe $tDNA $tsupercoils, $tallowing $tthem $tto $tstraighten
before $treplication
$t
C. Initiates $tDNA $tsynthesis $tin $tmultiple $tsites $tdown $tthe $tstrand, $tmaking $tthe $tprocess
more $tefficient
$t
D. Connects $tand $tlinks $tthe $tindividual $tpieces $tof $tnewly $tsynthesized $tDNA $tto
form $ta $tsingle $tstrand
$t
$ t $ t A. $ t 21. $ t Where $tis $ttelomeric $tDNA $tlocated?
A. At $tthe $ttips $tof $tthe $tp $tand $tq $tarms $tof $tchromosomes.
B. In $tthe $tmitochondria $tof $tall $tsomatic $tcells
C. Only $tin $tthe $tgerm $tcells $t(ova $tand $tsperm)
D. Within $tthe $thistones $tof $tthe $tsolenoid
NURSINGBYTES
$t
Genetics and Genomics in Nursing and Health Care
$t $t $t $t $t $t $t
by Theresa A. Beery, M. Linda Workman
$t $t $t $t $t $t
First Edition
$t
FULL TEST BANK!!! $t $t
NURSINGBYTES
, Chapter 1: DNA Structure and Function
$t $t $t $t $t
Multiple Choice
Identify the choice that best completes the statement or answers the question.
A. 1. In which body or cell area are most genes in humans located?
A. Nucleus
B. Mitochondrion
C. Cytoplasm
D. Plasma membrane
A. 2. Which condition or statement exemplifies the concept of genomics rather than genetics?
A. The gene for insulin is located on chromosome 11 in all people.
B. Expression of any single gene is dependent on inheriting two alleles.
C. Sex-linked recessive disorders affect males more often than females.
D. One allele for each gene is inherited from the mother, and one is inherited from the
father.
A. 3. What is the purpose of phosphorous in a DNA strand?
A. Linking the nucleotides into a strand
B. Holding complementary strands together
C. Ensuring that a purine is always paired with a pyrimidine
D. Preventing the separation of double-stranded DNA into single-stranded DNA
A. 4. What is the term used to define alternative forms of a gene that may result in different expression
of the trait coded for by that gene?
A. Alleles
B. Bases
C. Centromeres
D. Diploids
D. 5. What percentage of bases in a stretch of double-stranded DNA that contains 30% guanine (G)
bases would be adenine (A)?
A. 70%
B. 60%
C. 30%
D. 20%
C. 6. What is the term used to describe the organized picture of the paired chromosomes within a cell
used to determine whether chromosome numbers, structures, and banding patterns are normal?
A. Pedigree
B. Phenotype
C. Karyotype
D. Autotype
D. 7. What would be the sequence of DNA that is complementary to a DNA section with the base
sequence of GGTCAATCCTTAG?
A. GATTCCTAACTGG
B. TTGACCGAAGGCT
C. AACTGGCTTCCGA
D. CCAGTTAGGAATC
NURSINGBYTES
,$ t $ t B. 8. $ t Which $tof $tthese $tcomplementary $tbase $tpairs $tform $tthe $tstrongest $tor $t“tightest” $tassociation?
A. Adenine $tand $tthymine
B. Cytosine $tand $tguanine
C. Guanine $tand $tthymine
D. Cytosine $tand $tadenine
$ t $ t A 9. $ t What $tactivity $toccurs $tduring $tM $tphase $tof $tthe $tcell $tcycle?
A. The $tcell $tundergoes $tcytokinesis.
B. Activity $tstops, $tand $tthe $tcell $t“sleeps.”
C. All $tDNA $tis $tcompletely $treplicated.
D. The $tcell $tgreatly $tincreases $tprotein $tsynthesis.
$ t $ t B. $ t $ t 10. $ t Which $tchromosome $tnumber $trepresents $tthe $teuploid $tstate $tfor $tnormal $thuman $tsomatic $tcells?
A. 44
B. 46
C. 47
D. 48
$ t $ t A. $ t 11. $ t How $tdoes $tthe $tproteome $tdiffer $tfrom $tthe $tgenome?
A. The $tproteome $tchanges $tin $tresponse $tto $tintracellular $tand $textracellular $tsignals.
B. The $tgenome $tchanges $tin $tresponse $tto $tintracellular $tand $textracellular $tsignals.
C. The $tproteome $tis $tstable $tin $tsomatic $tcells $tand $tunstable $tin $tgerm $tcells,
$t whereas $tthe $tgenome $tis $tstable $tin $tboth $tsomatic $tcells $tand $tgerm $tcells.
D. The $tgenome $tis $tstable $tin $tsomatic $tcells $tand $tunstable $tin $tgerm $tcells, $twhereas
the $tproteome $tis $tstable $tin $tboth $tsomatic $tcells $tand $tgerm $tcells.
$t
$ t $ t C. $ t $ t 12. $ t What $tis $tthe $tmost $toutstanding $tfeature $tof $ta $tmature $thaploid $tcell?
A. It $tis $tusually $thomozygous.
B. The $tsex $tchromosomes $tare $tmissing.
C. Only $tone $tchromosome $tof $teach $tpair $tis $tpresent.
D. DNA $tsynthesis $toccurs $tafter $tmitosis $tinstead $tof $tbefore.
$ t $ t D. $ t $ t 13. $ t At $twhat $tphase $tof $tthe $tcell $tcycle $tare $tchromosomes $tvisible $tas $tseparate $tstructures?
A. G1
B. G2
C. S
D. M
$ t $ t B. $ t 14. $ t Which $tstatement $tabout $tthe $tcell $tcycle $tphase $tof $tG0 $ t is $ttrue?
A. Hyperplastic $tgrowth $tin $tplace $tof $thypertrophic $tgrowth
B. Performance $tof $tspecific $tdifferentiated $tfunctions
C. Initiation $tand $tcompletion $tof $tnucleokinesis
D. Replication $tof $tDNA
$ t $ t B. $ t 15. $ t What $tis $tthe $tresult $tof $tnormal $tDNA $treplication?
A. Formation $tof $ttwo $tnew $tdaughter $tcells
B. Formation $tof $ttwo $tidentical $tsets $tof $tDNA
C. Disappearance $tof $tthe $toriginal $tparent $tcell
D. Activation $tand $tattachment $tof $tspindle $tfibers
NURSINGBYTES
, $ t $ t A. $ t 16. $ t Which $tstatement $tregarding $tchromosome $tstructure $tor $tfunction $tis $ttrue?
A. The $tchromatids $tof $tany $tsingle $tchromosome $tare $tknown $tas $t“sister $tchromatids.”
B. The $tgenes $tlocated $ton $tthe $ttelomeres $tof $tchromosomes $tare $tidentical $tto $tthe
$t genes $tin $tthe $tcentromeres.
C. Immediately $tbefore $tthe $tmitosis $tphase $tof $tcell $tdivision, $tthe $tchromosomes $tof
all $tsomatic $tcells $tare $thaploid.
$t
D. A $tspecific $tgene $tallele $ton $tone $tchromosome $thas $ta $tcomplementary $tallele $ton $tthe
$tother $tchromosome $tof $ta $tpair.
$ t $ t C. $ t $ t 17. $ t Why $tdoes $ta $tperson $twith $tnormal $tchromosomes $tonly $thave $ttwo $talleles $tfor $tany $tsingle $tgene
$t trait?
A. A $tminimum $tof $ttwo $talleles $tis $trequired $tfor $tthe $texpression $tof $tmonogenic $ttraits.
B. When $ta $tdominant $tallele $tis $tpaired $twith $ta $trecessive $tallele, $tonly $tthe $tdominant
$t allele $tis $texpressed, $tand $tthe $trecessive $tallele $tis $tsilent.
C. One $tallele $tfor $tthe $tmonogenic $ttrait $tis $ton $tthe $tpaternally $tderived $tchromosome,
and $tthe $tother $tallele $tis $ton $tthe $tmaternally $tderived $tchromosome.
$t
D. Expression $tof $tmore $tthan $ttwo $talleles $tof $tany $tsingle-gene $ttrait $tresults $tin
$t enhanced $texpression $tof $trecessive $talleles $tand $tsuppressed $texpression $tof
$t dominant $talleles.
$ t $ t C 18. Under $twhat $tnormal $tcondition $tare $tgenotype $tand $tphenotype $talways $tthe $tsame?
$ t
A. Euploidy $tof $talleles
B. Aneuploidy $tof $talleles
C. Homozygosity $tof $talleles
D. Heterozygosity $tof $talleles
$t $ t D. $ t 19. $ t What $twould $tbe $tthe $texpected $tresult $tof $ta $tdrug $tthat $taffected $ta $tparticular $ttissue $tby
causing $tnew $tDNA $tto $tform $twith $tcovalent $tbonds $tinstead $tof $thydrogen $tbonds?
$t
A. None $tof $tthe $tcells $tin $tthe $taffected $ttissue $twould $tbe $table $tto $tleave $tG0 $ t and $tenter
$t the $tcell $tcycle.
B. Replication $tof $tDNA $twould $tresult $tin $tidentical $tDNA $tstrands $tinstead
of $tcomplementary $tstrands.
$t
C. Mitosis $tof $tcells $tin $tthe $ttissue $twould $tresult $tin $tthe $tproduction $tof $tthree $tnew
daughter $tcells $tinstead $tof $tjust $ttwo.
$t
D. The $tnew $tcells $tthat $tformed $twithin $tthis $ttissue $twould $tnot $tbe $table $tto $tcomplete $tthe
$t next $tround $tof $tmitosis $tsuccessfully.
$ t $ t B. $ t 20. $ t How $tdoes $tthe $tDNA $tenzyme $ttopoisomerase $tcontribute $tto $tDNA $treplication?
A. Unwinds $tthe $tdouble $thelix $tand $tseparates $tthe $tdouble-stranded $tDNA
B. Creates $ta $t“nick” $tin $tthe $tDNA $tsupercoils, $tallowing $tthem $tto $tstraighten
before $treplication
$t
C. Initiates $tDNA $tsynthesis $tin $tmultiple $tsites $tdown $tthe $tstrand, $tmaking $tthe $tprocess
more $tefficient
$t
D. Connects $tand $tlinks $tthe $tindividual $tpieces $tof $tnewly $tsynthesized $tDNA $tto
form $ta $tsingle $tstrand
$t
$ t $ t A. $ t 21. $ t Where $tis $ttelomeric $tDNA $tlocated?
A. At $tthe $ttips $tof $tthe $tp $tand $tq $tarms $tof $tchromosomes.
B. In $tthe $tmitochondria $tof $tall $tsomatic $tcells
C. Only $tin $tthe $tgerm $tcells $t(ova $tand $tsperm)
D. Within $tthe $thistones $tof $tthe $tsolenoid
NURSINGBYTES
