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Blood Bank Questions with Detailed Verified
Answers (100% Correct Answers) /Already Graded
A+
Which of the following set of conditions would NOT allow HDN to occur as a
result of Rh incompatibility:
Ans: Mother Rh-negative, father Rh-negative
What is the purpose of a major crossmatch?
Ans: Verify donor ABO packed-cell compatibility
The use of cells with known blood groups to confirm ABO typing is known as:
Ans: Reverse grouping
Fresh frozen plasma :
Ans: Should be transfused within 24 hours of thawing
What is the proper storage temperature for thawed Cryoprecipitate?
Ans: 20 - 24 ºC.
Most antibodies present in cord blood are of ________ origin.
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Ans: maternal
What are the possible ABO genotypes of offspring from parents whose
genotypes are OO and AB:
Ans: OA
OB
An aliquot of AS-1 red blood cells is being prepared from an intact packed cell
unit using a sterile connection device.
During the process of preparing an aliquot, the sterile device fails and blood
drips onto the counter from the product tubing. What should be done with
the primary unit?
Ans: Change the expiration date to 24 hours
Kernicterus due to high levels of unconjugated bilirubin can cause brain
damage in newborns suffering from severe HDFN.
Ans: True
The parents' blood types were AB and O. The blood group of any of their
children could ONLY be:
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Ans: Group A or B only
For the test results shown above, which of the following antibodies is most
likely to be causing the newborn's positive DAT?
Ans: anti-K
The correct answer is anti-K.
Both the mother and infant are group A, eliminating ABO HDFN.
We are given the cell ID information for each of the screening cells. Screen cell
1 is R1R1. Therefore these antigens are present: D,C, e.
Screen cell 2 is R2R2. Therefore these antigens are present: D,E,c
Screen cell 3 is rr. Therefore these antigens are present: c,e
The only cell that reacted was Screen cell 3. Both c and e are also present on
the nonreactive cells. The only choice that has not been eliminated is anti-K.
Also, the antibody screen reaction pattern (only cell 3 positive) is typical of anti-
K.
An urticarial transfusion reaction is characterized by:
Ans: Rash and hives
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Which one of the following is NOT a cause for donor deferral?
Ans: Weighs 115 pounds
Why do so few patients transfused with un-crossmatched red cells in an
emergency experience a hemolytic transfusion reaction? Select the one best
reason.
Ans: The incidence of unexpected red cell antibodies is relatively low.
What is the first step a transfusionist should take when a transfusion reaction
is suspected?
Ans: Stop the transfusion, but keep the intravenous line open with saline.
What is the fundamental purpose of the full, pre-transfusion crossmatch?
Ans: Detect antibodies in recipient serum/plasma that react with donor red
cells.
At what phase of antibody screen testing is it most important to read the
reactions in order to detect clinically significant antibodies?
Ans: AHG
© Get it right 2025 Getaway - Stuvia US All rights reserved
Blood Bank Questions with Detailed Verified
Answers (100% Correct Answers) /Already Graded
A+
Which of the following set of conditions would NOT allow HDN to occur as a
result of Rh incompatibility:
Ans: Mother Rh-negative, father Rh-negative
What is the purpose of a major crossmatch?
Ans: Verify donor ABO packed-cell compatibility
The use of cells with known blood groups to confirm ABO typing is known as:
Ans: Reverse grouping
Fresh frozen plasma :
Ans: Should be transfused within 24 hours of thawing
What is the proper storage temperature for thawed Cryoprecipitate?
Ans: 20 - 24 ºC.
Most antibodies present in cord blood are of ________ origin.
© Get it right 2025 Getaway - Stuvia US All rights reserved
,Click here for more: Scholars nexus
Ans: maternal
What are the possible ABO genotypes of offspring from parents whose
genotypes are OO and AB:
Ans: OA
OB
An aliquot of AS-1 red blood cells is being prepared from an intact packed cell
unit using a sterile connection device.
During the process of preparing an aliquot, the sterile device fails and blood
drips onto the counter from the product tubing. What should be done with
the primary unit?
Ans: Change the expiration date to 24 hours
Kernicterus due to high levels of unconjugated bilirubin can cause brain
damage in newborns suffering from severe HDFN.
Ans: True
The parents' blood types were AB and O. The blood group of any of their
children could ONLY be:
© Get it right 2025 Getaway - Stuvia US All rights reserved
,Click here for more: Scholars nexus
Ans: Group A or B only
For the test results shown above, which of the following antibodies is most
likely to be causing the newborn's positive DAT?
Ans: anti-K
The correct answer is anti-K.
Both the mother and infant are group A, eliminating ABO HDFN.
We are given the cell ID information for each of the screening cells. Screen cell
1 is R1R1. Therefore these antigens are present: D,C, e.
Screen cell 2 is R2R2. Therefore these antigens are present: D,E,c
Screen cell 3 is rr. Therefore these antigens are present: c,e
The only cell that reacted was Screen cell 3. Both c and e are also present on
the nonreactive cells. The only choice that has not been eliminated is anti-K.
Also, the antibody screen reaction pattern (only cell 3 positive) is typical of anti-
K.
An urticarial transfusion reaction is characterized by:
Ans: Rash and hives
© Get it right 2025 Getaway - Stuvia US All rights reserved
, Click here for more: Scholars nexus
Which one of the following is NOT a cause for donor deferral?
Ans: Weighs 115 pounds
Why do so few patients transfused with un-crossmatched red cells in an
emergency experience a hemolytic transfusion reaction? Select the one best
reason.
Ans: The incidence of unexpected red cell antibodies is relatively low.
What is the first step a transfusionist should take when a transfusion reaction
is suspected?
Ans: Stop the transfusion, but keep the intravenous line open with saline.
What is the fundamental purpose of the full, pre-transfusion crossmatch?
Ans: Detect antibodies in recipient serum/plasma that react with donor red
cells.
At what phase of antibody screen testing is it most important to read the
reactions in order to detect clinically significant antibodies?
Ans: AHG
© Get it right 2025 Getaway - Stuvia US All rights reserved
