Pharmacology eIllustrated e Reviews e7th eEdition eWhalen eTest eBank
e TABLE eOF eCONTENT
Chapter e 1: e Pharmacokinetics
Chapter e2: eDrug–Receptor eInteractions eand ePharmacodynamics
e Chapter e3: e The e Autonomic eNervous eSystem
Chapter e4: eCholinergic eAgonists
eChapter e5: eCholinergic
eAntagonists eChapter e6:
eAdrenergic eAgonists eChapter e7:
eAdrenergic eAntagonists
Chapter e8: eDrugs efor eNeurodegenerative eDiseases
eChapter e9: eAnxiolytic eand eHypnotic eDrugs
Chapter e10: eAntidepressants
eChapter e11: eAntipsychotic eDrugs
eChapter e12: eDrugs efor eEpilepsy
eChapter e13: eAnesthetics
Chapter e 14: e Opioids
Chapter e15: eDrugs eof eAbuse
eChapter e16: eCNS eStimulants
eChapter e17: eAntihypertensives
eChapter e18: eDiuretics
Chapter e 19: e Heart e Failure
Chapter e20: eAntiarrhythmics
eChapter e21: eAntianginal eDrugs
Chapter e22: eAnticoagulants eand eAntiplatelet eAgents
e Chapter e23: eDrugs efor eHyperlipidemia
Chapter e24: ePituitary eand eThyroid
eChapter e25: eDrugs efor eDiabetes
Chapter e26: eEstrogens eand eAndrogens
eChapter e27: eAdrenal eHormones
Chapter e 28: e Drugs e for e Obesity
Chapter e29: eDrugs efor eDisorders eof ethe eRespiratory eSystem
e Chapter e30: eAntihistamines
Chapter e31: eGastrointestinal eand eAntiemetic eDrugs
eChapter e32: eDrugs efor eUrologic e Disorders
Chapter e 33: e Drugs e for e Anemia
Chapter e34: eDrugs efor eDermatologic eDisorders
eChapter e35: eDrugs efor eBone eDisorders
Chapter e36: eAnti-inflammatory, eAntipyretic, eand e Analgesic eAgents
e Chapter e37: e Principles eof e Antimicrobial e Therapy
Chapter e 38: e Cell eWall e Inhibitors
Chapter e 39: e Protein e Synthesis e Inhibitors
Chapter e40: eQuinolones, eFolic eAcid e Antagonists, e and e Urinary e Tract eAntiseptics
eChapter e41: eAntimycobacterial eDrugs
Chapter e42: eAntifungal eDrugs
eChapter e43: eAntiprotozoal eDrugs
eChapter e44: eAnthelmintic eDrugs
eChapter e45: eAntiviral eDrugs
Chapter e 46: e Anticancer e Drugs
Chapter e47: eImmunosuppressants
eChapter e48: eClinical eToxicology
,
,3. The enurse eis eteaching ea epatient ewho ewill ebe edischarged ehome ewith ea eprescription efor ean eenteric-
coated etablet. eWhich estatement eby ethe epatient e indicates eunderstanding eof ethe eteaching?
e
a. I emay ecrush ethe etablet eand eput eit ein eapplesauce eto eimprove eabsorption.
b. I eshould e consume eacidic efoodseto eenhance eabsorption eof ethis emedication.
c. I e should e expect e a edelay ein eonset e of ethe edrugs eeffects eafter etaking ethe etablet.
d. I eshould etake ethis emedication ewith ehigh-fat efoods eto eimprove eits eaction.
eANS: eC
Enteric-coated etablets eresist edisintegration ein ethe eacidic eenvironment eof ethe estomach eand
disintegrate ewhen ethey ereach ethe esmall eintestine. eThere eis eusually esome edelay ein eonset eof eactions
e
after etaking ethese emedications. eEnteric-coated etablets eshould enot ebe ecrushed eor echewed, ewhich
e
would ealter ethe etime eand elocation eof eabsorption. eAcidic efoods ewill enot eenhance ethe eabsorption eof
e
the emedication. eThe epatient eshould enot eto eeat ehigh-fat efood ebefore eingesting ean eenteric-coated
e
tablet, ebecause ehigh-fat efoods edecrease ethe eabsorption erate.
e
DIF: eCOGNITIVE eLEVEL: eApplying e(Application) eREF: edm e3
TOP: eNURSING ePROCESS: eNursing eIntervention
e
MSC: eNCLEX: ePhysiological eIntegrity: ePharmacological eand eParenteral eTherapies
4. A epatient ewho eis enewly ediagnosed ewith etype e1 ediabetes emellitus easks ewhy einsulin emust ebe
given eby esubcutaneous einjection einstead eof eby emouth. eThe enurse ewilleexplain ethat ethis eis
e
because
e
a. absorption eis e diminished e byethe efirst-pass eeffects ein ethe eliver.
b. absorption eis efaster ewhen einsulin eis egiven esubcutaneously.
c. digestive eenzymes ein ethe egastrointestinal etract eprevent eabsorption.
d. the eoral eformeis eless epredictable ewith emore eadverse eeffects.
ANS: eC
e
Insulin, egrowth ehormones, eand eother eprotein-based edrugs eare edestroyed ein ethe esmall eintestine eby
digestive eenzymes eand emust ebe egiven eparenterally. eBecause einsulin eis edestroyed eby edigestive
e
enzymes, eit ewould enot emake eit eto ethe eliver efor emetabolism ewith ea efirst-pass eeffect. eSubcutaneous
e
tissue ehas efewer eblood evessels, eso eabsorption eis eslower ein esuch etissue. eInsulin eis egiven
e
subcutaneously ebecause eit eis edesirable eto ehave eit eabsorb eslowly.
e
DIF: eCOGNITIVE eLEVEL: eUnderstanding e(Comprehension) eREF: edm e3
TOP: eNURSING ePROCESS: eNursing eIntervention: ePatient eTeaching
e
MSC: eNCLEX: ePhysiological eIntegrity: ePharmacological eand eParenteral eTherapies
Page e 2 e of e 507
Plusbay.Plus
, 5. The enurse eis epreparing eto eadminister ean eoral emedication ethat eis ewater-soluble. eThe enurse
understands ethat ethis edrug
e
a. must ebe etaken eon ean eemptyestomach.
b. requires eactive etransport eforeabsorption.
c. should e be etaken ewith efatty efoods.
d. will ereadily ediffuse einto ethe egastrointestinal etract.
ANS: eB
e
Water-soluble e drugs erequire ea e carrier eenzyme e or eprotein e to epass ethrough ethe eGI emembrane.
DIF: eCOGNITIVE eLEVEL: eUnderstanding e(Comprehension) eREF: edm e4
TOP: eNURSING ePROCESS: eNursing eIntervention
e
MSC: eNCLEX: ePhysiological eIntegrity: ePharmacological eand eParenteral eTherapies
6. A enurse eis epreparing eto eadminister ean eoral edrug ethat eis ebest eabsorbed ein ean eacidic eenvironment.
How ewill ethe enurse egive ethe edrug?
e
a. On ean eempty estomach
b. With ea efull eglass e of ewater
c. With efood
d. With ehigh-fat efood
ANS: eC
e
Food ecan estimulate ethe eproduction eof egastric eacid eso emedications erequiring ean eacidic eenvironment
should ebe egiven ewith ea emeal. eHigh-fat efoods eare euseful efor edrugs ethat e are elipid esoluble.
e
DIF: eCOGNITIVE eLEVEL: eApplying e(Application) eREF: edm e4
TOP: eNURSING ePROCESS: eNursing eIntervention
e
MSC: eNCLEX: ePhysiological eIntegrity: ePharmacological eand eParenteral eTherapies
7. The enurse eis epreparing ean einjectable edrug eand ewants eto eadminister eit efor erapid eabsorption. eHow
will ethe enurse egive ethis emedication?
e
a. IM einto ethe edeltoid e muscle
b. IM einto ethe egluteal emuscle
c. SubQ einto eabdominal etissue
d. SubQ einto ethe eupper earm
ANS: eA
e
Page e 3 e of e 507
Plusbay.Plus
e TABLE eOF eCONTENT
Chapter e 1: e Pharmacokinetics
Chapter e2: eDrug–Receptor eInteractions eand ePharmacodynamics
e Chapter e3: e The e Autonomic eNervous eSystem
Chapter e4: eCholinergic eAgonists
eChapter e5: eCholinergic
eAntagonists eChapter e6:
eAdrenergic eAgonists eChapter e7:
eAdrenergic eAntagonists
Chapter e8: eDrugs efor eNeurodegenerative eDiseases
eChapter e9: eAnxiolytic eand eHypnotic eDrugs
Chapter e10: eAntidepressants
eChapter e11: eAntipsychotic eDrugs
eChapter e12: eDrugs efor eEpilepsy
eChapter e13: eAnesthetics
Chapter e 14: e Opioids
Chapter e15: eDrugs eof eAbuse
eChapter e16: eCNS eStimulants
eChapter e17: eAntihypertensives
eChapter e18: eDiuretics
Chapter e 19: e Heart e Failure
Chapter e20: eAntiarrhythmics
eChapter e21: eAntianginal eDrugs
Chapter e22: eAnticoagulants eand eAntiplatelet eAgents
e Chapter e23: eDrugs efor eHyperlipidemia
Chapter e24: ePituitary eand eThyroid
eChapter e25: eDrugs efor eDiabetes
Chapter e26: eEstrogens eand eAndrogens
eChapter e27: eAdrenal eHormones
Chapter e 28: e Drugs e for e Obesity
Chapter e29: eDrugs efor eDisorders eof ethe eRespiratory eSystem
e Chapter e30: eAntihistamines
Chapter e31: eGastrointestinal eand eAntiemetic eDrugs
eChapter e32: eDrugs efor eUrologic e Disorders
Chapter e 33: e Drugs e for e Anemia
Chapter e34: eDrugs efor eDermatologic eDisorders
eChapter e35: eDrugs efor eBone eDisorders
Chapter e36: eAnti-inflammatory, eAntipyretic, eand e Analgesic eAgents
e Chapter e37: e Principles eof e Antimicrobial e Therapy
Chapter e 38: e Cell eWall e Inhibitors
Chapter e 39: e Protein e Synthesis e Inhibitors
Chapter e40: eQuinolones, eFolic eAcid e Antagonists, e and e Urinary e Tract eAntiseptics
eChapter e41: eAntimycobacterial eDrugs
Chapter e42: eAntifungal eDrugs
eChapter e43: eAntiprotozoal eDrugs
eChapter e44: eAnthelmintic eDrugs
eChapter e45: eAntiviral eDrugs
Chapter e 46: e Anticancer e Drugs
Chapter e47: eImmunosuppressants
eChapter e48: eClinical eToxicology
,
,3. The enurse eis eteaching ea epatient ewho ewill ebe edischarged ehome ewith ea eprescription efor ean eenteric-
coated etablet. eWhich estatement eby ethe epatient e indicates eunderstanding eof ethe eteaching?
e
a. I emay ecrush ethe etablet eand eput eit ein eapplesauce eto eimprove eabsorption.
b. I eshould e consume eacidic efoodseto eenhance eabsorption eof ethis emedication.
c. I e should e expect e a edelay ein eonset e of ethe edrugs eeffects eafter etaking ethe etablet.
d. I eshould etake ethis emedication ewith ehigh-fat efoods eto eimprove eits eaction.
eANS: eC
Enteric-coated etablets eresist edisintegration ein ethe eacidic eenvironment eof ethe estomach eand
disintegrate ewhen ethey ereach ethe esmall eintestine. eThere eis eusually esome edelay ein eonset eof eactions
e
after etaking ethese emedications. eEnteric-coated etablets eshould enot ebe ecrushed eor echewed, ewhich
e
would ealter ethe etime eand elocation eof eabsorption. eAcidic efoods ewill enot eenhance ethe eabsorption eof
e
the emedication. eThe epatient eshould enot eto eeat ehigh-fat efood ebefore eingesting ean eenteric-coated
e
tablet, ebecause ehigh-fat efoods edecrease ethe eabsorption erate.
e
DIF: eCOGNITIVE eLEVEL: eApplying e(Application) eREF: edm e3
TOP: eNURSING ePROCESS: eNursing eIntervention
e
MSC: eNCLEX: ePhysiological eIntegrity: ePharmacological eand eParenteral eTherapies
4. A epatient ewho eis enewly ediagnosed ewith etype e1 ediabetes emellitus easks ewhy einsulin emust ebe
given eby esubcutaneous einjection einstead eof eby emouth. eThe enurse ewilleexplain ethat ethis eis
e
because
e
a. absorption eis e diminished e byethe efirst-pass eeffects ein ethe eliver.
b. absorption eis efaster ewhen einsulin eis egiven esubcutaneously.
c. digestive eenzymes ein ethe egastrointestinal etract eprevent eabsorption.
d. the eoral eformeis eless epredictable ewith emore eadverse eeffects.
ANS: eC
e
Insulin, egrowth ehormones, eand eother eprotein-based edrugs eare edestroyed ein ethe esmall eintestine eby
digestive eenzymes eand emust ebe egiven eparenterally. eBecause einsulin eis edestroyed eby edigestive
e
enzymes, eit ewould enot emake eit eto ethe eliver efor emetabolism ewith ea efirst-pass eeffect. eSubcutaneous
e
tissue ehas efewer eblood evessels, eso eabsorption eis eslower ein esuch etissue. eInsulin eis egiven
e
subcutaneously ebecause eit eis edesirable eto ehave eit eabsorb eslowly.
e
DIF: eCOGNITIVE eLEVEL: eUnderstanding e(Comprehension) eREF: edm e3
TOP: eNURSING ePROCESS: eNursing eIntervention: ePatient eTeaching
e
MSC: eNCLEX: ePhysiological eIntegrity: ePharmacological eand eParenteral eTherapies
Page e 2 e of e 507
Plusbay.Plus
, 5. The enurse eis epreparing eto eadminister ean eoral emedication ethat eis ewater-soluble. eThe enurse
understands ethat ethis edrug
e
a. must ebe etaken eon ean eemptyestomach.
b. requires eactive etransport eforeabsorption.
c. should e be etaken ewith efatty efoods.
d. will ereadily ediffuse einto ethe egastrointestinal etract.
ANS: eB
e
Water-soluble e drugs erequire ea e carrier eenzyme e or eprotein e to epass ethrough ethe eGI emembrane.
DIF: eCOGNITIVE eLEVEL: eUnderstanding e(Comprehension) eREF: edm e4
TOP: eNURSING ePROCESS: eNursing eIntervention
e
MSC: eNCLEX: ePhysiological eIntegrity: ePharmacological eand eParenteral eTherapies
6. A enurse eis epreparing eto eadminister ean eoral edrug ethat eis ebest eabsorbed ein ean eacidic eenvironment.
How ewill ethe enurse egive ethe edrug?
e
a. On ean eempty estomach
b. With ea efull eglass e of ewater
c. With efood
d. With ehigh-fat efood
ANS: eC
e
Food ecan estimulate ethe eproduction eof egastric eacid eso emedications erequiring ean eacidic eenvironment
should ebe egiven ewith ea emeal. eHigh-fat efoods eare euseful efor edrugs ethat e are elipid esoluble.
e
DIF: eCOGNITIVE eLEVEL: eApplying e(Application) eREF: edm e4
TOP: eNURSING ePROCESS: eNursing eIntervention
e
MSC: eNCLEX: ePhysiological eIntegrity: ePharmacological eand eParenteral eTherapies
7. The enurse eis epreparing ean einjectable edrug eand ewants eto eadminister eit efor erapid eabsorption. eHow
will ethe enurse egive ethis emedication?
e
a. IM einto ethe edeltoid e muscle
b. IM einto ethe egluteal emuscle
c. SubQ einto eabdominal etissue
d. SubQ einto ethe eupper earm
ANS: eA
e
Page e 3 e of e 507
Plusbay.Plus
