WGU D115 ADVANCED PATHOPHYSIOLOGY OA EXAM 2025
|D115 OA - WGU D115 OA EXAM REAL QUESTIONS AND
CORRECT ANSWERS WITH RATIONALES LATEST
2025/2026, EXCELLENT GUIDE
What is the most common indication for genetic counseling?
-Maternal Age
-Drug exposure during the first trimester
-Increased maternal alpha-fetoprotein
-History of previous still birth
The FNP schedules a 38-year-old primigravida (first time pregnancy) for an
amniocentesis at 16
weeks gestation. The FNP would explain that the purpose of this procedure is to:
-Assess for the possibility of twins
-Determine bilirubin level
-Perform genetic studies
-Assess L/S ratio
Perform Genetic studies
Feedback: This woman's age puts her at risk for Down Syndrome
In the most commonly seen form of Turner Syndrome, how is the X chromosome
affected?
-Each cell has only one X chromosome
-Some cells have two X chromosomes, while other cells have only one.
Page | 1
,-Each cell has two X chromosomes, but part of the chromosome is missing.
-Each cell has an extra X chromosome.
Each cell has only one X chromosome
Feedback: 45% of persons with Turner Syndrome have monosomy X meaning
there is only one copy of the X chromosome in each cell
The FNP is assessing a newborn who is demonstrating a high-pitched cry,
microcephaly, hypertelorism, hypotonia, and a low birth weight. The FNP would suspect
which of the following genetic conditions?
-Down Syndrome
-Cri du chat
-Charge syndrome
-Duncan disease
Feedback: The clinical symptoms of cri du chat syndrome usually include a
high-pitched cat-like cry, mental retardation, delayed development,
distinctive facial features, small head size (microcephaly), widely-spaced
eyes (hypertelorism), low birth weight and weak muscle tone (hypotonia) in
infancy.
When explaining the types of adaptive immunity, the FNP student is aware that:
-Adaptive immunity is a cell-mediated immune response which is carried out by T cells
and B cells.
-Adaptive immunity is the level of immunity that all persons are born with.
-Adaptive immunity occurs when antibodies are passed from the mother to the fetus.
-Adaptive immunity occurs through immunization
Adaptive immunity is a cell-mediated immune response which is carried
out by T cells and B cells.
Page | 2
, Feedback: There are two types of adaptive immunity responses: the cell-
mediated immune response, which is carried out by T cells, and the
humoral immune response, which is controlled by activated B cells and
antibodies.
A woman has sustained a traumatic brain injury. She is able to follow simple commands
and can manipulate objects. Which term describes this state?
-Coma
-Persistent vegetative state
-Minimally conscious
-Locked-in syndrome
Minimally conscious
Feedback: When responses to the environment are seen, the patient is said
to be in a minimally conscious state
Age and the admission of the Glasgow Coma Scale (GCS) are important diagnostic
factors in TBI. Which GCS score describes a severe TBI?
13-15
12-13
9-12
3-8
3-8
Page | 3
, Feedback: The GCS is scored between 3 and 15, 3 being the worst and 15
the best.
Which term describes recurrent, intrusive thoughts or impulses?
-Hallucinations
-Compulsions
-Obsessions
-Delusions
Obsessions
Feedback: Obsessions are recurrent and persistent thoughts, impulses, or
images that cause distressing emotions such as anxiety or disgust.
During an intake interview with a 26-year-old man diagnosed with generalized anxiety
disorder, the FNP might observe what type of behavior?
-An inflated sense of self
-Constant relation to future events
-Inability to concentrate and irritability when questioned
-Nervousness and fear of the FNP during the interview
Inability to concentrate and irritability when questioned
Feedback: Impaired concentration and irritability are major characteristics
of GAD.
The FNP would expect which symptoms in a patient with a diagnosis of schizophrenia?
-High energy with varying sleep patterns and non stop conversation.
-Extreme and frequent mood swings with hyperactivity and difficulty concentrating.
Page | 4
|D115 OA - WGU D115 OA EXAM REAL QUESTIONS AND
CORRECT ANSWERS WITH RATIONALES LATEST
2025/2026, EXCELLENT GUIDE
What is the most common indication for genetic counseling?
-Maternal Age
-Drug exposure during the first trimester
-Increased maternal alpha-fetoprotein
-History of previous still birth
The FNP schedules a 38-year-old primigravida (first time pregnancy) for an
amniocentesis at 16
weeks gestation. The FNP would explain that the purpose of this procedure is to:
-Assess for the possibility of twins
-Determine bilirubin level
-Perform genetic studies
-Assess L/S ratio
Perform Genetic studies
Feedback: This woman's age puts her at risk for Down Syndrome
In the most commonly seen form of Turner Syndrome, how is the X chromosome
affected?
-Each cell has only one X chromosome
-Some cells have two X chromosomes, while other cells have only one.
Page | 1
,-Each cell has two X chromosomes, but part of the chromosome is missing.
-Each cell has an extra X chromosome.
Each cell has only one X chromosome
Feedback: 45% of persons with Turner Syndrome have monosomy X meaning
there is only one copy of the X chromosome in each cell
The FNP is assessing a newborn who is demonstrating a high-pitched cry,
microcephaly, hypertelorism, hypotonia, and a low birth weight. The FNP would suspect
which of the following genetic conditions?
-Down Syndrome
-Cri du chat
-Charge syndrome
-Duncan disease
Feedback: The clinical symptoms of cri du chat syndrome usually include a
high-pitched cat-like cry, mental retardation, delayed development,
distinctive facial features, small head size (microcephaly), widely-spaced
eyes (hypertelorism), low birth weight and weak muscle tone (hypotonia) in
infancy.
When explaining the types of adaptive immunity, the FNP student is aware that:
-Adaptive immunity is a cell-mediated immune response which is carried out by T cells
and B cells.
-Adaptive immunity is the level of immunity that all persons are born with.
-Adaptive immunity occurs when antibodies are passed from the mother to the fetus.
-Adaptive immunity occurs through immunization
Adaptive immunity is a cell-mediated immune response which is carried
out by T cells and B cells.
Page | 2
, Feedback: There are two types of adaptive immunity responses: the cell-
mediated immune response, which is carried out by T cells, and the
humoral immune response, which is controlled by activated B cells and
antibodies.
A woman has sustained a traumatic brain injury. She is able to follow simple commands
and can manipulate objects. Which term describes this state?
-Coma
-Persistent vegetative state
-Minimally conscious
-Locked-in syndrome
Minimally conscious
Feedback: When responses to the environment are seen, the patient is said
to be in a minimally conscious state
Age and the admission of the Glasgow Coma Scale (GCS) are important diagnostic
factors in TBI. Which GCS score describes a severe TBI?
13-15
12-13
9-12
3-8
3-8
Page | 3
, Feedback: The GCS is scored between 3 and 15, 3 being the worst and 15
the best.
Which term describes recurrent, intrusive thoughts or impulses?
-Hallucinations
-Compulsions
-Obsessions
-Delusions
Obsessions
Feedback: Obsessions are recurrent and persistent thoughts, impulses, or
images that cause distressing emotions such as anxiety or disgust.
During an intake interview with a 26-year-old man diagnosed with generalized anxiety
disorder, the FNP might observe what type of behavior?
-An inflated sense of self
-Constant relation to future events
-Inability to concentrate and irritability when questioned
-Nervousness and fear of the FNP during the interview
Inability to concentrate and irritability when questioned
Feedback: Impaired concentration and irritability are major characteristics
of GAD.
The FNP would expect which symptoms in a patient with a diagnosis of schizophrenia?
-High energy with varying sleep patterns and non stop conversation.
-Extreme and frequent mood swings with hyperactivity and difficulty concentrating.
Page | 4