Test Bank for Understanding
Pharmacology Essentials for
Medication Safety, 2nd Edition by M.
Linda Workman & LaCharity Chapter
1-32 | Complete Guide
Bactericidal - ANSWERS--A drug that reduces the number of bacteria by killing them
directly
Bacteriostatic - ANSWERS--A drug that reduces the number of bacteria by preventing
them from dividing and growing rather than directly killing them
Cell Wall Synthesis Inhibitors - ANSWERS--A class of antibacterial drugs that kills
susceptible bacteria by preventing them from forming strong, protective cell walls
Drug Generation - ANSWERS--Stage of drug development in which later generations
are changed slightly to improve their effectiveness or means of administration
Fluoroquinolones - ANSWERS--A group of drugs from the DNA synthesis inhibitor class
tha tenter bacterial cells and prevent bacteria reproduction by suppressing the action of
two enzymes important in making bacterial DNA
,Metabolism inhibitors - ANSWERS--A class of antibacterial drugs that interfere with
bacterial reproduction by preventing the bacteria from making folic acid
Antibiotic Resistance - ANSWERS--The ability of a bacterium to resist the effects of
antibacterials
Protein Synthesis Inhibitors - ANSWERS--A large class of antibacterial drugs that
includes aminoglycosides, macrolides, and tetracyclines, which prevent bacteria from
making proteins important to their life cycles and infective processes
Susceptible Organisms - ANSWERS--Bacteria or other organisms that either can be
killed by or have their reproduction reduced by an antibacterial drug
Virulence - ANSWERS--The measure of how well bacteria can invade and spread
despite a normal immune response.
Bactericidal and Bacteriostatic Drugs pg 115
If a person's immune system is not working well, he or she would benefit from a
_______ drug and not a _______ drug. - ANSWERS--Bactericidal
Bacteriostatic
Review of Related Physiologic And Pathophysiology pg 114
_________ bacteria coexist with us, causing no systemic disease or tissue damage and
are considered normal flora - ANSWERS--Nonpathogenic
Review of Related Physiologic And Pathophysiology pg 114
_____ _____ are the nonpathogenic bacteria that we always have on skin, mucous
membranes and in the digestive tract. - ANSWERS--Normal Flora
Spectrum of efficacy - ANSWERS--A measure of how many different types of bacteria a
drug can kill or prevent from growing
Review of Related Physiologic And Pathophysiology pg 114
________ bacteria cause disease and tissue damage only in someone whose immune
system is not working well. - ANSWERS--Opportunistic
Bacterial features pg 115
The _______ of bacteria is a measure of how well they can invade and spread despite a
normal immune response. - ANSWERS--Virulence
Bactericidal and Bacteriostatic Drugs pg 115
,Some antibacterial drugs are _______, which means that they can kill bacteria directly. -
ANSWERS--Bactericidal
Bactericidal and Bacteriostatic Drugs pg 115
Other antibacterial drugs are _________, which means that they prevent bacteria from
reproducing until the body's own white blood cells and antibodies get rid of the, -
ANSWERS--Bacteriostatic
Memory Jogger pg 115
_________ bacteria are those that can cause damage or tissue disease
________ bacteria do not cause disease or damage unless they overgrow or are
present in a susceptible body area
_________ bacteria cause disease or tissue damage only when the immune system is
impaired - ANSWERS--Pathogenic
Non Pathogenic
Opportunistic
Memory Jogger pg 115
________ drugs directly kill bacteria
_________ drugs stop them from reproducing while the immune system kills the
bacteria - ANSWERS--Bactericidal
Bacteriosttic
Spectrum Of Efficacy pg 116
Antibacterial drugs are sometimes described by their _____ _____ ______, which is a
measure of how many different types of bacteria the drug can kill or prevent from
growing. - ANSWERS--Spectrum of Efficacy
Spectrum Of Efficacy pg 116
A _______-spectrum antibacterial drug is effective against only a few types of bacteria -
ANSWERS--Narrow
Spectrum Of Efficacy pg 116
An ________-spectrum antibacterial drug is effective against more types of bacteria. -
ANSWERS--Extended
Spectrum Of Efficacy pg 116
, A _________-spectrum antibacterial drug is effective against a wide range of bacteria,
both gram-positive and gram-negative - ANSWERS--Broad
Spectrum Of Efficacy pg 116
What is the most common method to identify bacteria? - ANSWERS--Culture and
Sensitivity (C&S)
General Issues in Antibacterial Therapy pg 116
Side effects common to all antibacterial drugs include: - ANSWERS--INtestinal
disturbances that can range from an increase in the number of bowel movements to
severe diarrhea.
General Issues in Antibacterial Therapy pg 116
Another side effect resulting from the loss of normal flora in the mouth and vagina are
______ infections. - ANSWERS--Yeast
General Issues in Antibacterial Therapy pg 116
Yeast infections in the mount is known as ________. _______ makes food taste bad
and can cause gum disease. - ANSWERS--Thrush
Memory Jogger pg 116
The goal of antibacterial therapy is to: - ANSWERS--Kill bacteria or prevent their
reproduction without harming the patient
Memory Jogger pg 116
When normal flora are killed by antibiotic therapy, common problems the patient may
develop: - ANSWERS--Diarrhea and the overgrowth of yeast in the mouth and vagina
General Issues in Antibacterial Therapy pg 117
Other names for Pseudomembranous colitis include: - ANSWERS--Antibiotic-
associated colitis
Necrotizing colitis
General Issues in Antibacterial Therapy pg 117
BEfore giving any antibacterial drug: - ANSWERS--Ask the patient if he or she has any
drug allergies. Notify the prescriber if the patient has an allergy to the drug. If he or she
does have an allergy to a drug and is to receive it anyway, check with the prescriber
Pharmacology Essentials for
Medication Safety, 2nd Edition by M.
Linda Workman & LaCharity Chapter
1-32 | Complete Guide
Bactericidal - ANSWERS--A drug that reduces the number of bacteria by killing them
directly
Bacteriostatic - ANSWERS--A drug that reduces the number of bacteria by preventing
them from dividing and growing rather than directly killing them
Cell Wall Synthesis Inhibitors - ANSWERS--A class of antibacterial drugs that kills
susceptible bacteria by preventing them from forming strong, protective cell walls
Drug Generation - ANSWERS--Stage of drug development in which later generations
are changed slightly to improve their effectiveness or means of administration
Fluoroquinolones - ANSWERS--A group of drugs from the DNA synthesis inhibitor class
tha tenter bacterial cells and prevent bacteria reproduction by suppressing the action of
two enzymes important in making bacterial DNA
,Metabolism inhibitors - ANSWERS--A class of antibacterial drugs that interfere with
bacterial reproduction by preventing the bacteria from making folic acid
Antibiotic Resistance - ANSWERS--The ability of a bacterium to resist the effects of
antibacterials
Protein Synthesis Inhibitors - ANSWERS--A large class of antibacterial drugs that
includes aminoglycosides, macrolides, and tetracyclines, which prevent bacteria from
making proteins important to their life cycles and infective processes
Susceptible Organisms - ANSWERS--Bacteria or other organisms that either can be
killed by or have their reproduction reduced by an antibacterial drug
Virulence - ANSWERS--The measure of how well bacteria can invade and spread
despite a normal immune response.
Bactericidal and Bacteriostatic Drugs pg 115
If a person's immune system is not working well, he or she would benefit from a
_______ drug and not a _______ drug. - ANSWERS--Bactericidal
Bacteriostatic
Review of Related Physiologic And Pathophysiology pg 114
_________ bacteria coexist with us, causing no systemic disease or tissue damage and
are considered normal flora - ANSWERS--Nonpathogenic
Review of Related Physiologic And Pathophysiology pg 114
_____ _____ are the nonpathogenic bacteria that we always have on skin, mucous
membranes and in the digestive tract. - ANSWERS--Normal Flora
Spectrum of efficacy - ANSWERS--A measure of how many different types of bacteria a
drug can kill or prevent from growing
Review of Related Physiologic And Pathophysiology pg 114
________ bacteria cause disease and tissue damage only in someone whose immune
system is not working well. - ANSWERS--Opportunistic
Bacterial features pg 115
The _______ of bacteria is a measure of how well they can invade and spread despite a
normal immune response. - ANSWERS--Virulence
Bactericidal and Bacteriostatic Drugs pg 115
,Some antibacterial drugs are _______, which means that they can kill bacteria directly. -
ANSWERS--Bactericidal
Bactericidal and Bacteriostatic Drugs pg 115
Other antibacterial drugs are _________, which means that they prevent bacteria from
reproducing until the body's own white blood cells and antibodies get rid of the, -
ANSWERS--Bacteriostatic
Memory Jogger pg 115
_________ bacteria are those that can cause damage or tissue disease
________ bacteria do not cause disease or damage unless they overgrow or are
present in a susceptible body area
_________ bacteria cause disease or tissue damage only when the immune system is
impaired - ANSWERS--Pathogenic
Non Pathogenic
Opportunistic
Memory Jogger pg 115
________ drugs directly kill bacteria
_________ drugs stop them from reproducing while the immune system kills the
bacteria - ANSWERS--Bactericidal
Bacteriosttic
Spectrum Of Efficacy pg 116
Antibacterial drugs are sometimes described by their _____ _____ ______, which is a
measure of how many different types of bacteria the drug can kill or prevent from
growing. - ANSWERS--Spectrum of Efficacy
Spectrum Of Efficacy pg 116
A _______-spectrum antibacterial drug is effective against only a few types of bacteria -
ANSWERS--Narrow
Spectrum Of Efficacy pg 116
An ________-spectrum antibacterial drug is effective against more types of bacteria. -
ANSWERS--Extended
Spectrum Of Efficacy pg 116
, A _________-spectrum antibacterial drug is effective against a wide range of bacteria,
both gram-positive and gram-negative - ANSWERS--Broad
Spectrum Of Efficacy pg 116
What is the most common method to identify bacteria? - ANSWERS--Culture and
Sensitivity (C&S)
General Issues in Antibacterial Therapy pg 116
Side effects common to all antibacterial drugs include: - ANSWERS--INtestinal
disturbances that can range from an increase in the number of bowel movements to
severe diarrhea.
General Issues in Antibacterial Therapy pg 116
Another side effect resulting from the loss of normal flora in the mouth and vagina are
______ infections. - ANSWERS--Yeast
General Issues in Antibacterial Therapy pg 116
Yeast infections in the mount is known as ________. _______ makes food taste bad
and can cause gum disease. - ANSWERS--Thrush
Memory Jogger pg 116
The goal of antibacterial therapy is to: - ANSWERS--Kill bacteria or prevent their
reproduction without harming the patient
Memory Jogger pg 116
When normal flora are killed by antibiotic therapy, common problems the patient may
develop: - ANSWERS--Diarrhea and the overgrowth of yeast in the mouth and vagina
General Issues in Antibacterial Therapy pg 117
Other names for Pseudomembranous colitis include: - ANSWERS--Antibiotic-
associated colitis
Necrotizing colitis
General Issues in Antibacterial Therapy pg 117
BEfore giving any antibacterial drug: - ANSWERS--Ask the patient if he or she has any
drug allergies. Notify the prescriber if the patient has an allergy to the drug. If he or she
does have an allergy to a drug and is to receive it anyway, check with the prescriber
