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confusion, sweating, and tremors
What is serotonin syndrome?
, occurs w/ any drug which increases serotonin
What are the clinical manifestations of serotonin syndrome?
Rapid onset of diarrhea, restlessness, agitation, hyperreflexia, and fluctuations in vital signs
can turn into seizures, uncontrolled shivering, and muscle rigidity
TCAs (tricyclic antidepressants)
Amitriptyline (Elavil) used for depression
Anticholinergic effects and orthostatic hypotension may occur
unpleasant and serious side effects can occur
Trough
lowest medication level in the blood before the next dose
Peak
the highest concentration of a drug in the patient's bloodstream
Ondansetron (Zofran)
Antiemetic that work best if given prior to the trigger of the nausea
Sucralfate (Carafate)
Used to treat/prevent ulcers in intestines
Puts coating over ulcers
Side effects: Constipation, dry mouth, upset stomach, nausea, gas
When should sucralfate (Carafate) be administered and why?
On an empty stomach one hour prior to each meal and at bedtime to create a protective
coating over the ulcer and reduce inflammation
Acyclovir (Zovirax)
Antiretroviral used to treat genital herpes, shingles, HIV.
What are the precautions for Acyclovir?
administer with food, increase fluid intake, and begin therapy with the first onset of
symptoms.
* can cause nephrotoxicity and administer slowly
What is the reversal agent for benzodiazepines?
Flumazenil (Romazicon)
Benzodiazepines
medications used for anxiety and insomnia