TEST BANK for Psychopharmacology Drugs the Brain and Behavior 4th Edition by Meyer Nursing, All Chapters 1-20

PSYCHOPHARMACOLOGY nTEST nBANK

,PSYCHOPHARMACOLOGY nTEST nBANK


Test nBank
to naccompany
Psychopharmacology, nThird nEdition
Meyer n• nQuenzer


Chapter n1: nPrinciples nof nPharmacology

Multiple nChoice

1. n refer(s) nto nspecific nmolecular nchanges nthat noccur nwhen na ndrug
nbinds nto na nparticular ntarget nsite nor nreceptor, nwhile are nthe nresulting
nwidespread nalterationsnin nfunction.
a. Drug naction; ntherapeutic neffects
b. Side neffects; ndrug neffects
c. Therapeutic neffects; nside neffects
d. Drug naction; ndrug neffects
Answer: nd
Textbook nReference: nPharmacology: nThe nScience nof nDrug nAction

2. After ndrug nadministration nhas noccurred, nthe namount nof ndrug nin nthe nblood
nthat nis nfree ntonbind nat nspecific ntarget nsites nis nreferred nto nas
a. the ntherapeutic ndose.
b. first-pass neffects.
c. bioavailability.
d. ED50.
Answer: nc
Textbook nReference: nPharmacokinetic nFactors nDetermining nDrug nAction

3. The nspecific nmolecular nchanges nthat noccur nwhen na ndrug nbinds nto na
nparticular ntarget nsitenor nreceptor nare nreferred nto nas
a. drug neffects.
b. drug naction.
c. side neffects.
d. placebo neffects.
Answer: nb
Textbook nReference: nPharmacology: nThe nScience nof nDrug nAction

4. Which nof nthe nfollowing nis nnot na npossible nexplanation nfor nplacebo neffects?
a. Pavlovian nconditioning
b. Genetic nvariation
c. Drug ncompetition
d. Expectation nof noutcome
Answer: nc
Textbook nReference: nPharmacology: nThe nScience nof nDrug nAction


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5. The administration nof noxytocin nhas nbeen nproposed nas na ntreatment nfor
nautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: nc
Textbook nReference: nPharmacokinetic nFactors nDetermining nDrug nAction

6. Which nfactor ndoes nnot naffect nthe npharmacokinetics nof na ndrug?
a. Route nof nadministration
b. Lipid nsolubility
c. Depot nbinding
d. Drug naction
Answer: nd
Textbook nReference: nPharmacokinetic nFactors nDetermining nDrug nAction

7. First-pass nmetabolism noccurs nwhen ndrugs nare ntaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: na
Textbook nReference: nPharmacokinetic nFactors nDetermining nDrug nAction

8. The narea npostrema nis none narea nin nthe nbrain nwhere nthe is nnot ncomplete.
a. cerebrospinal nfluid
b. blood–brain nbarrier
c. choroid nplexus
d. phospholipid nmembrane
Answer: nb
Textbook nReference: nPharmacokinetic nFactors nDetermining nDrug nAction

9. First-pass nmetabolism noccurs nwith norally nadministered ndrugs nbecause
a. their nabsorption nis nslowed nby nfood.
b. drugs nabsorbed ninto nthe nbloodstream nfrom nthe nstomach ngo nto nthe nliver
non nthe nway ntongeneral ncirculation.
c. drugs nmust nfirst nsurvive nthe nacidic nenvironment nof nthe nstomach.
d. salivary nenzymes nin nthe nmouth nbegin nthe nprocess nof nmetabolism.
Answer: nb
Textbook nReference: nPharmacokinetic nFactors nDetermining nDrug nAction

10. Toxic nsubstances nin nthe nblood ntrigger na nvomiting nresponse nby nactivating nthe
a. blood–brain nbarrier.
b. choroid nplexus.
c. area npostrema.
d. median neminence.


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Answer: nc
Textbook nReference: nPharmacokinetic nFactors nDetermining nDrug nAction

11. Drugs nadministered n_ have nthe nmost nrapid nonset nof naction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: nd
Textbook nReference: nPharmacokinetic nFactors nDetermining nDrug nAction

12. Ionization nof na ndrug ndepends non nthe of nthe nsolution nand nthe of
nthendrug.
a. pH; npKa
b. pKa; npH
c. concentration; nlipid nsolubility
d. pH; nconcentration
Answer: na
Textbook nReference: nPharmacokinetic nFactors nDetermining nDrug nAction

13. The nabsorption nof na ndrug ndepends non nall nof nthe nfollowing nexcept
a. lipid nsolubility.
b. ionization.
c. body ntemperature.
d. the nconcentration nof nthe ndrug.
Answer: nc
Textbook nReference: nPharmacokinetic nFactors nDetermining nDrug nAction

14. Drugs nthat nare should nbe navoided nby nwomen nof nchildbearing nage.
a. teratogenic
b. able nto ncross nthe nplacental nbarrier
c. psychoactive
d. highly nlipid-soluble
Answer: na
Textbook nReference: nPharmacokinetic nFactors nDetermining nDrug nAction

15. Agents nthat ninduce ndevelopmental nabnormalities nin na nfetus nare nknown nas
a. psychoactive ndrugs.
b. illicit ndrugs.
c. teratogens.
d. placental ndrugs.
Answer: nc
Textbook nReference: nPharmacokinetic nFactors nDetermining nDrug nAction

16. Depot nbinding nis nsaid nto noccur nwhen ndrugs
a. bind nto ntheir ntarget nsites.



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