NR565 / NR565 Advanced Pharmacology
Fundamentals Midterm / Final Exam|
Questions and 100 % Correct Answers |
Rated A Quiz bank | LATEST, 2025 /
2026 | Chamberlain College
1. Kasey fractured his ankle in two places and is asking for medication for his pain. The
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appropriate first-line medication would be:
ak ak ak ak ak
- Acetaminophen with hydrocodone (Vicodin) ak ak ak
2. Jack, age 8, has attention deficit disorder (ADD) and is prescribed methylphenidate
ak ak ak ak ak ak ak ak ak ak ak
(Ritalin). He and his parents should be educated about the side effects of
ak ak ak ak ak ak ak ak ak ak ak ak ak
methylphenidate, which are:
ak ak ak
- Insomnia and decreased appetite ak ak ak
3. Monitoring fora child on methylphenidate for attention deficit hyperactivity disorder
ak ak ak ak ak ak ak ak ak ak
(ADHD) includes:
ak ak
- ADHD symptoms ak
- Routine height and weight checks ak ak ak ak
- Amount of methylphenidate being used ak ak ak ak
4. When prescribing Adderall (amphetamineand dextroamphetamine) toadults with ADHD the
ak ak ak ak ak ak ak ak ak ak
nurse practitioner will need to monitor:
ak ak ak ak ak ak
- Blood pressure ak
5. Common mistakes practitioners make in treating anxiety disorders include:
ak ak ak ak ak ak ak ak
- Thinking a partial response to medication is acceptable ak ak ak ak ak ak ak
6. An appropriate first-line drug to try for mild to moderate generalized anxiety disorder
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would be:
ak ak
- Buspirone (Buspar) ak
7. An appropriate drug to initially treat panic disorder is:
ak ak ak ak ak ak ak ak
- Diazepam (Valium) ak
8. Prior to starting antidepressants, patients should have laboratory testing to rule out:
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- Hypothyroidism
,9. David is a 34-year-old patient who is starting on paroxetine (Paxil) for depression.
ak ak ak ak ak ak ak ak ak ak ak ak
David's education regarding his medication would include:
ak ak ak ak ak ak ak
- He may experience sexual dysfunction beginning a month after he starts therapy.
ak ak ak ak ak ak ak ak ak ak ak
10. Jamison has been prescribed citalopram (Celexa) to treat his depression. Education regarding
ak ak ak ak ak ak ak ak ak ak ak
howquickly selectiveserotonin reuptakeinhibitor (SSRI) antidepressants work would be:
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- Appetite and concentration improve in the first 1 to 2 weeks. ak ak ak ak ak ak ak ak ak ak
11. Theracial difference in drug pharmacokinetics seen in American Indian or Alaskan
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Natives are:
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- Largely unknown due to lack of studies of this population ak ak ak ak ak ak ak ak ak
12. Pharmacokinetics among Asians are universal to all the Asian ethnic groups. ak ak ak ak ak ak ak ak ak ak
A. True
B. False
13. Alterations in drug metabolism among Asians may lead to: ak ak ak ak ak ak ak ak
- Slower metabolism of antidepressants, requiring lower doses ak ak ak ak ak ak
14. Asians from Eastern Asia are known to be fast acetylators. Fast acetylators:
ak ak ak ak ak ak ak ak ak ak ak
- Require higher doses of drugs metabolized by acetylization to achieve efficacy ak ak ak ak ak ak ak ak ak ak
15. Hispanic native healers (curanderas): ak ak ak
A. Are not heavily utilized by Hispanics who immigrate to the United States
ak ak ak ak ak ak ak ak ak ak ak
B. Use herbs and teas in their treatment of illness
ak ak ak ak ak ak ak ak
C. Provide unsafe advice to Hispanics and should not be trusted
ak ak ak ak ak ak ak ak ak
D. Need to be licensed in their home country in order to practice in the United States
ak ak ak ak ak ak ak ak ak ak ak ak ak ak ak a k
16. Genetic polymorphisms account for differences in metabolism, including:
ak ak ak ak ak ak ak
- Poor metabolizers, who lack a working enzyme ak ak ak ak ak ak
- Intermediate metabolizers, who have one working, wild-type allele and one mutant ak ak ak ak ak ak ak ak ak ak
allele ak
- Extensive metabolizers, with two normally functioning alleles ak ak ak ak ak ak
17. Up to 21% of Asians are ultra-rapid 2D6 metabolizers, leading to:
ak ak ak ak ak ak ak ak ak ak
- Increased dosages needed of drugs metabolized by 2D6, such as the selective ak ak ak ak ak ak ak ak ak ak ak
serotonin reuptake inhibitors
ak ak ak
18. Drugs that use CYP 3A4 isoenzymes for metabolism may:
ak ak ak ak ak ak ak ak
- Induce the metabolism of another drug ak ak ak ak ak
, - Inhibit the metabolism of another drug ak ak ak ak ak
19. Rifampin is a nonspecific CYP450 inducer that may: ak ak ak ak ak ak ak
- Induce the metabolism of drugs, such as oral contraceptives, leading to therapeutic
ak ak ak ak ak ak ak ak ak ak ak
failure ak
20. Inhibition of P-glycoprotein by a drug such as quinidine may lead to:
ak ak ak ak ak ak ak ak ak ak ak
- Increased levels of a co-administered drug, such as digoxin, that requires P- ak ak ak ak ak ak ak ak ak ak ak
glycoprotein for absorption and elimination
ak ak ak ak ak
21. Warfarin resistance may be seen in patients with VCORC1 mutation, leading to:
ak ak ak ak ak ak ak ak ak ak ak
- Decreased response to warfarin ak ak ak
22. Genetictesting for VCORC1 mutation to assess potential warfarin resistance isrequired prior
ak ak ak ak ak ak ak ak ak ak ak ak
to prescribing warfarin.
ak ak ak
A. True
B. False
23. Pharmacogenetic testing is required by the U.S. Food and Drug Administration prior to ak ak ak ak ak ak ak ak ak ak ak ak
prescribing:
ak
- Cetuximab
24. Carbamazepine has a Black Box Warning recommending testing for theHLA-B*1502 ak ak ak ak ak ak ak ak ak ak
allele in patients with Asian ancestry prior to starting therapy due to:
ak ak ak ak ak ak ak ak ak ak ak ak
- Increased risk for Stevens-Johnson syndrome in Asian patients with HLA-B*1502 ak ak ak ak ak ak ak ak ak
allele ak
25. A genetic variation in how the metabolite of the cancer drug irinotecan SN-38 is
ak ak ak ak ak ak ak ak ak ak ak ak ak
inactivated by the body may lead to
ak ak ak ak ak ak ak
- Increased adverse drug reactions, such as neutropenia ak ak ak ak ak ak
26. Patients who have a poor metabolism phenotype will have:
ak ak ak ak ak ak ak ak
- Slowed metabolism of a prodrug into an active drug, leading to accumulation of
ak ak ak ak ak ak ak ak ak ak ak ak
prodrug ak
27. A patient's nutritional intakeand laboratory results reflect hypoalbuminemia. This is
ak ak ak ak ak ak ak ak ak ak
critical to prescribing because:
ak ak ak ak
- Distribution of drugs to target tissue may be affected. ak ak ak ak ak ak ak ak
28. Drugs that have a significant first-pass effect:
ak ak ak ak ak ak
- Are rapidly metabolized by the liver and may have little if any desired action
ak ak ak ak ak ak ak ak ak ak ak ak ak
29. The route of excretion of a volatile drug will likely be the:
ak ak ak ak ak ak ak ak ak ak ak
- Lungs
Fundamentals Midterm / Final Exam|
Questions and 100 % Correct Answers |
Rated A Quiz bank | LATEST, 2025 /
2026 | Chamberlain College
1. Kasey fractured his ankle in two places and is asking for medication for his pain. The
ak ak ak ak ak ak ak ak ak ak ak ak ak ak ak
appropriate first-line medication would be:
ak ak ak ak ak
- Acetaminophen with hydrocodone (Vicodin) ak ak ak
2. Jack, age 8, has attention deficit disorder (ADD) and is prescribed methylphenidate
ak ak ak ak ak ak ak ak ak ak ak
(Ritalin). He and his parents should be educated about the side effects of
ak ak ak ak ak ak ak ak ak ak ak ak ak
methylphenidate, which are:
ak ak ak
- Insomnia and decreased appetite ak ak ak
3. Monitoring fora child on methylphenidate for attention deficit hyperactivity disorder
ak ak ak ak ak ak ak ak ak ak
(ADHD) includes:
ak ak
- ADHD symptoms ak
- Routine height and weight checks ak ak ak ak
- Amount of methylphenidate being used ak ak ak ak
4. When prescribing Adderall (amphetamineand dextroamphetamine) toadults with ADHD the
ak ak ak ak ak ak ak ak ak ak
nurse practitioner will need to monitor:
ak ak ak ak ak ak
- Blood pressure ak
5. Common mistakes practitioners make in treating anxiety disorders include:
ak ak ak ak ak ak ak ak
- Thinking a partial response to medication is acceptable ak ak ak ak ak ak ak
6. An appropriate first-line drug to try for mild to moderate generalized anxiety disorder
ak ak ak ak ak ak ak ak ak ak ak ak
would be:
ak ak
- Buspirone (Buspar) ak
7. An appropriate drug to initially treat panic disorder is:
ak ak ak ak ak ak ak ak
- Diazepam (Valium) ak
8. Prior to starting antidepressants, patients should have laboratory testing to rule out:
ak ak ak ak ak ak ak ak ak ak ak
- Hypothyroidism
,9. David is a 34-year-old patient who is starting on paroxetine (Paxil) for depression.
ak ak ak ak ak ak ak ak ak ak ak ak
David's education regarding his medication would include:
ak ak ak ak ak ak ak
- He may experience sexual dysfunction beginning a month after he starts therapy.
ak ak ak ak ak ak ak ak ak ak ak
10. Jamison has been prescribed citalopram (Celexa) to treat his depression. Education regarding
ak ak ak ak ak ak ak ak ak ak ak
howquickly selectiveserotonin reuptakeinhibitor (SSRI) antidepressants work would be:
ak ak ak ak ak ak ak ak ak ak ak
- Appetite and concentration improve in the first 1 to 2 weeks. ak ak ak ak ak ak ak ak ak ak
11. Theracial difference in drug pharmacokinetics seen in American Indian or Alaskan
ak ak ak ak ak ak ak ak ak ak ak
Natives are:
ak ak
- Largely unknown due to lack of studies of this population ak ak ak ak ak ak ak ak ak
12. Pharmacokinetics among Asians are universal to all the Asian ethnic groups. ak ak ak ak ak ak ak ak ak ak
A. True
B. False
13. Alterations in drug metabolism among Asians may lead to: ak ak ak ak ak ak ak ak
- Slower metabolism of antidepressants, requiring lower doses ak ak ak ak ak ak
14. Asians from Eastern Asia are known to be fast acetylators. Fast acetylators:
ak ak ak ak ak ak ak ak ak ak ak
- Require higher doses of drugs metabolized by acetylization to achieve efficacy ak ak ak ak ak ak ak ak ak ak
15. Hispanic native healers (curanderas): ak ak ak
A. Are not heavily utilized by Hispanics who immigrate to the United States
ak ak ak ak ak ak ak ak ak ak ak
B. Use herbs and teas in their treatment of illness
ak ak ak ak ak ak ak ak
C. Provide unsafe advice to Hispanics and should not be trusted
ak ak ak ak ak ak ak ak ak
D. Need to be licensed in their home country in order to practice in the United States
ak ak ak ak ak ak ak ak ak ak ak ak ak ak ak a k
16. Genetic polymorphisms account for differences in metabolism, including:
ak ak ak ak ak ak ak
- Poor metabolizers, who lack a working enzyme ak ak ak ak ak ak
- Intermediate metabolizers, who have one working, wild-type allele and one mutant ak ak ak ak ak ak ak ak ak ak
allele ak
- Extensive metabolizers, with two normally functioning alleles ak ak ak ak ak ak
17. Up to 21% of Asians are ultra-rapid 2D6 metabolizers, leading to:
ak ak ak ak ak ak ak ak ak ak
- Increased dosages needed of drugs metabolized by 2D6, such as the selective ak ak ak ak ak ak ak ak ak ak ak
serotonin reuptake inhibitors
ak ak ak
18. Drugs that use CYP 3A4 isoenzymes for metabolism may:
ak ak ak ak ak ak ak ak
- Induce the metabolism of another drug ak ak ak ak ak
, - Inhibit the metabolism of another drug ak ak ak ak ak
19. Rifampin is a nonspecific CYP450 inducer that may: ak ak ak ak ak ak ak
- Induce the metabolism of drugs, such as oral contraceptives, leading to therapeutic
ak ak ak ak ak ak ak ak ak ak ak
failure ak
20. Inhibition of P-glycoprotein by a drug such as quinidine may lead to:
ak ak ak ak ak ak ak ak ak ak ak
- Increased levels of a co-administered drug, such as digoxin, that requires P- ak ak ak ak ak ak ak ak ak ak ak
glycoprotein for absorption and elimination
ak ak ak ak ak
21. Warfarin resistance may be seen in patients with VCORC1 mutation, leading to:
ak ak ak ak ak ak ak ak ak ak ak
- Decreased response to warfarin ak ak ak
22. Genetictesting for VCORC1 mutation to assess potential warfarin resistance isrequired prior
ak ak ak ak ak ak ak ak ak ak ak ak
to prescribing warfarin.
ak ak ak
A. True
B. False
23. Pharmacogenetic testing is required by the U.S. Food and Drug Administration prior to ak ak ak ak ak ak ak ak ak ak ak ak
prescribing:
ak
- Cetuximab
24. Carbamazepine has a Black Box Warning recommending testing for theHLA-B*1502 ak ak ak ak ak ak ak ak ak ak
allele in patients with Asian ancestry prior to starting therapy due to:
ak ak ak ak ak ak ak ak ak ak ak ak
- Increased risk for Stevens-Johnson syndrome in Asian patients with HLA-B*1502 ak ak ak ak ak ak ak ak ak
allele ak
25. A genetic variation in how the metabolite of the cancer drug irinotecan SN-38 is
ak ak ak ak ak ak ak ak ak ak ak ak ak
inactivated by the body may lead to
ak ak ak ak ak ak ak
- Increased adverse drug reactions, such as neutropenia ak ak ak ak ak ak
26. Patients who have a poor metabolism phenotype will have:
ak ak ak ak ak ak ak ak
- Slowed metabolism of a prodrug into an active drug, leading to accumulation of
ak ak ak ak ak ak ak ak ak ak ak ak
prodrug ak
27. A patient's nutritional intakeand laboratory results reflect hypoalbuminemia. This is
ak ak ak ak ak ak ak ak ak ak
critical to prescribing because:
ak ak ak ak
- Distribution of drugs to target tissue may be affected. ak ak ak ak ak ak ak ak
28. Drugs that have a significant first-pass effect:
ak ak ak ak ak ak
- Are rapidly metabolized by the liver and may have little if any desired action
ak ak ak ak ak ak ak ak ak ak ak ak ak
29. The route of excretion of a volatile drug will likely be the:
ak ak ak ak ak ak ak ak ak ak ak
- Lungs
