NR 546 / NR546 Final Exam Tested Questions with Revised Answers (Latest 2025/2026), (A+ Guarantee). Advanced Pharmacology Psychopharmacology for the Psychiatric-Mental Health Nurse Practitioner.

NR 546 / NR546 Final Exam Tested Questions with Revised
Answers (Latest 2025/2026), (A+ Guarantee). Advanced
Pharmacology Psychopharmacology for the Psychiatric-
Mental Health Nurse Practitioner.


QUESTION: Are the PMHNP and other staff liable if the client has an allergic reaction or
adverse side effects to the drugs used for chemical restraint? ✓✓Correct Answer- No.

The client has been court-ordered to take the prescribed medications and the standing order
for chemical restraints is approved. The PMHNP and other staff are not liable if the patient
has an allergic reaction or adverse side effects.



QUESTION: How does reviewing the genetic makeup of a client help guide the PMHNP in
selecting medication for clients? ✓✓Correct Answer- -Genetic testing can assist by
providing more information on how clients may respond to certain psychotropic medications

-provides information on how a client may break down and metabolize medications based
on the cytochrome P450 system.



QUESTION: Tanrıkulu and Erbaş (2020) investigated identical twins to determine the
presence of an inherited link for schizophrenia and why one twin may develop schizophrenia
when the other does not. When two people have 100% identical DNA, why don't both
persons develop the exact illnesses? Studies of identical Danish twins found that if one twin
had schizophrenia, the other twin had a 50% lifetime risk of developing schizophrenia
(Lemvigh et al., 2020). Why is there only half the risk? ✓✓Correct Answer- Both
environmental and psychosocial stressors can impact mental health. Although twins may
have identical genes, their gene expression may be different.



There may be an environmental exposure that turned a gene "on" that should have been
"off" for one twin to develop schizophrenia and not the other.



QUESTION: central sulcus ✓✓Correct Answer- separates the frontal lobe from the parietal
lobe



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,QUESTION: frontal lobe ✓✓Correct Answer- associated with movement, intelligence,
abstract thinking



QUESTION: broca's area ✓✓Correct Answer- speech production



QUESTION: temporal lobe ✓✓Correct Answer- involves object identification and auditory
signals



QUESTION: cerebellum ✓✓Correct Answer- coordination



QUESTION: wernicke's area ✓✓Correct Answer- speech comprehension



QUESTION: occipital lobe ✓✓Correct Answer- primary visual area



QUESTION: parietal lobe ✓✓Correct Answer- keeps us alert to what is going on around us



QUESTION: sensory cortex ✓✓Correct Answer- pain, heat, and other sensations



QUESTION: motor cortex ✓✓Correct Answer- movement



QUESTION: hippocampus ✓✓Correct Answer- involved in both memory and anxiety



QUESTION: nucleus accumbens ✓✓Correct Answer- involved in the reward process



QUESTION: thalamus ✓✓Correct Answer- involved in sensory organ and motor command
processing




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, QUESTION: striatum ✓✓Correct Answer- involved in complex motor actions, also links
cognition to motor actions



QUESTION: limbic system ✓✓Correct Answer- includes circuits that are associated with
pleasure and reward



QUESTION: basal ganglia ✓✓Correct Answer- group of structures involved in voluntary
motor movements



QUESTION: amygdala ✓✓Correct Answer- involved in emotional regulation and perception
of odors



QUESTION: corpus callosum ✓✓Correct Answer- controls the communication between the
two brain hemispheres



QUESTION: white matter ✓✓Correct Answer- contains nerve fibers that connect neurons
from different regions into functional circuits



QUESTION: grey matter ✓✓Correct Answer- contains nerve cells and dendrites



QUESTION: brain tissue ✓✓Correct Answer- made up of grey matter and white matter



QUESTION: dorsal striatum ✓✓Correct Answer- involved in complex motor actions and
linkage of cognition to motor actions

-main input area for basal ganglia

*activated when anticipating or engaging in pleasure



QUESTION: The field of epigenetics is rapidly growing and can help explain how gene
expression is: ✓✓Correct Answer- influenced by environmental factors and how epigenetics
contributes to the manifestation of mental illness

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, QUESTION: How does epigenetics impact a person's mental health? ✓✓Correct Answer-
internal or external factors activate portions of the genome that result in the manifestation
of mental health symptoms

-activation is often a result of a stressful event, which, when combined with the genetic risk,
results in the disease

-genes being on or off

-occurrence of symptoms may be the result of inheritance of an abnormal gene or of normal
genes being "on" when they should be "off."



QUESTION: Types of epigenetic changes: ✓✓Correct Answer- DNA Methylation

Histone modification

Non-coding RNA



QUESTION: The potential legal and ethical issues impacting mental health treatment must
also be taken into account, including: ✓✓Correct Answer- -informed consent

-competence to make healthcare decisions

-off-label prescribing



QUESTION: Informed consent ✓✓Correct Answer- Clients have the right to receive enough
information to make decisions about treatment.

-must also be informed about potential risks associated with medications.

-have the right to refuse treatment

-cannot be forcibly medicated in non-emergencies. However, clients can be forcibly
medicated if they are violent toward themselves or others and when less restrictive methods
have failed



QUESTION: Compliance ✓✓Correct Answer- A court order may be issued for a client to
receive treatment against their wishes if they are considered a danger to themselves or
others.

-Examples: clients with schizophrenia or sex offenders

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