Test Bank - for Understanding Pharmacology Essentials
for Medication Safety, 3rd Edition by M. Linda Workman &
LaCharity, All Chapters 1-32
Absorption - Correct Answer--Movement of a drug from the outside of the body into the blood stream.
Agonist - Correct Answer--An extrinsic drug that activates the receptor site of a cell and mimics the
actions of naturally occurring drugs.
Antagonist - Correct Answer--An extrinsic drug that blocks the receptor site of a cell, preventing the
naturally occurring substance from binding to the receptor.
Bioavailability - Correct Answer--The percentage of a drug dose that actually reaches the blood.
Black Box Warning - Correct Answer--A notice that a drug may produce serious or even life threatening
effects in some people in addition to its beneficial effects.
Cytoxic - Correct Answer--A drug action that is intended to kill a cell or organism.
Distribution - Correct Answer--The extent that a drug absorbed into the bloodstream spreads into the
three body water components.
Duration of Action - Correct Answer--The length of time a drug is present in the blood at or above the
level needed to produce an effect or response.
Extrinsic Drugs - Correct Answer--Drugs that are man made or derived from another species; not made
by the human body.
First pass loss - Correct Answer--Rapid inactivation or elimination of oral drugs as a result of liver
metabolism.
Generic Name - Correct Answer--National and international public drug name created by the United
States Adopted NamesCouncil to indicate the usual use or chemical composition of a drug.
, Half Life - Correct Answer--Time san needed for one half of a drug dose to be eliminated.
High Alert Drug - Correct Answer--A drug that has an increased risk of causing patient harm if it is used in
error.
Loading Dose - Correct Answer--The first dose of a drug that is larger than all subsequent doses of the
same drug; used when it takes more drug to reach steady state that it does to maintain it.
Mechanism of Action - Correct Answer--Exactly how, at the cellular level, a drug changes the activity of a
cell.
Minimum Effective
Concentration - Correct Answer--The smallest amount of drug necessary in the blood or target tissue to
result in a measurable intended action.
Percutaneous Route - Correct Answer--Movement of a drug from the outside of the body to the inside
through the skin or mucous membranes.
Pharmacodynamics - Correct Answer--Ways in which drugs work to change body function.
Pharmacokinetics - Correct Answer--How the body changes drugs; drug metabolism.
Physiologic Effects - Correct Answer--The change in body function as an income of the mechanism of
action off a drug.
Receptors - Correct Answer--Physical place on or in a cell where a drug can bind and interact.
Sequestration - Correct Answer--The trapping of drugs within certain body tissues, delaying their
elimination and extending their duration of action.
for Medication Safety, 3rd Edition by M. Linda Workman &
LaCharity, All Chapters 1-32
Absorption - Correct Answer--Movement of a drug from the outside of the body into the blood stream.
Agonist - Correct Answer--An extrinsic drug that activates the receptor site of a cell and mimics the
actions of naturally occurring drugs.
Antagonist - Correct Answer--An extrinsic drug that blocks the receptor site of a cell, preventing the
naturally occurring substance from binding to the receptor.
Bioavailability - Correct Answer--The percentage of a drug dose that actually reaches the blood.
Black Box Warning - Correct Answer--A notice that a drug may produce serious or even life threatening
effects in some people in addition to its beneficial effects.
Cytoxic - Correct Answer--A drug action that is intended to kill a cell or organism.
Distribution - Correct Answer--The extent that a drug absorbed into the bloodstream spreads into the
three body water components.
Duration of Action - Correct Answer--The length of time a drug is present in the blood at or above the
level needed to produce an effect or response.
Extrinsic Drugs - Correct Answer--Drugs that are man made or derived from another species; not made
by the human body.
First pass loss - Correct Answer--Rapid inactivation or elimination of oral drugs as a result of liver
metabolism.
Generic Name - Correct Answer--National and international public drug name created by the United
States Adopted NamesCouncil to indicate the usual use or chemical composition of a drug.
, Half Life - Correct Answer--Time san needed for one half of a drug dose to be eliminated.
High Alert Drug - Correct Answer--A drug that has an increased risk of causing patient harm if it is used in
error.
Loading Dose - Correct Answer--The first dose of a drug that is larger than all subsequent doses of the
same drug; used when it takes more drug to reach steady state that it does to maintain it.
Mechanism of Action - Correct Answer--Exactly how, at the cellular level, a drug changes the activity of a
cell.
Minimum Effective
Concentration - Correct Answer--The smallest amount of drug necessary in the blood or target tissue to
result in a measurable intended action.
Percutaneous Route - Correct Answer--Movement of a drug from the outside of the body to the inside
through the skin or mucous membranes.
Pharmacodynamics - Correct Answer--Ways in which drugs work to change body function.
Pharmacokinetics - Correct Answer--How the body changes drugs; drug metabolism.
Physiologic Effects - Correct Answer--The change in body function as an income of the mechanism of
action off a drug.
Receptors - Correct Answer--Physical place on or in a cell where a drug can bind and interact.
Sequestration - Correct Answer--The trapping of drugs within certain body tissues, delaying their
elimination and extending their duration of action.
