Gene Mutations and DNA Repair Review
UPDATED ACTUAL Exam Questions and
CORRECT Answers
The following DNA sequence 5'-TGCGATCC-3' is mutated to 5'-TGCGAGCC-3'.This is an
example of which type of mutation? - CORRECT ANSWER - transversion
A bacterial cell that is incapable of synthesizing an essential amino acid and therefore requires
supplemented medium in order to survive is an example of a/an... - CORRECT ANSWER -
NOT auxotroph
The following DNA sequence 5'-GATCCGAT-3' is mutated to 5'-GATCGAT-3'.This is an
example of which type of mutation? - CORRECT ANSWER - Deletion
The following DNA sequence 5'-TGCGATCC-3' is mutated to 5'-TGCAATCC-3'.This is an
example of which type of mutation? - CORRECT ANSWER - Transition
The following DNA sequence 5'-TGCGATCC-3' is mutated to produce 5'-TGCGATAC-3'.This is
an example of which type of mutation? - CORRECT ANSWER - Transversion
Which of the following chemical mutagen is most likely to cause a frameshift mutation? -
CORRECT ANSWER - Proflavin
nitrous acid and
5-bromouracil cause transition mutations
Which of the following pieces of evidence/statements supports the concept that "Mutation is
non-adaptive"? - CORRECT ANSWER - NOT A small proportion of colonies exposed to
antibiotic will survive due to the presence of an antibiotic resistance mutation.
, The base analog 5-Bromouracil is capable of base pairing with which of the following bases? -
CORRECT ANSWER - i) Adenine
ii) Guanine
bonds to A and G and induces transition mutations
If the following fragment of a non-template (coding) DNA strand 5'-ATGCCAGAG-3' was
mutated to produce 5'-ATGCCATAG-3' it would result in which of the following? - CORRECT
ANSWER - a non-sense mutation
GAG -> UAG (stop)
Which of the following is an example of a tri-nucleotide repeat expansion disease? - CORRECT
ANSWER - Huntington's disease
Which of the following is NOT a factor which influences the rate of spontaneous mutation? -
CORRECT ANSWER - environmental / selective pressure
Acridine dyes are most likely to cause which type of mutation? - CORRECT ANSWER -
Frameshifts
The deletion of 2 consecutive nucleotides in a DNA sequence would result in which type of
mutation? - CORRECT ANSWER - Frameshift mutation
deletion of 1+ bases
Because tautomeric shifts are transient, they do not cause permanent mutations. - CORRECT
ANSWER - False
Tautomeric shifts typically result in which type of mutation? - CORRECT ANSWER - more
than 1 of the above
UPDATED ACTUAL Exam Questions and
CORRECT Answers
The following DNA sequence 5'-TGCGATCC-3' is mutated to 5'-TGCGAGCC-3'.This is an
example of which type of mutation? - CORRECT ANSWER - transversion
A bacterial cell that is incapable of synthesizing an essential amino acid and therefore requires
supplemented medium in order to survive is an example of a/an... - CORRECT ANSWER -
NOT auxotroph
The following DNA sequence 5'-GATCCGAT-3' is mutated to 5'-GATCGAT-3'.This is an
example of which type of mutation? - CORRECT ANSWER - Deletion
The following DNA sequence 5'-TGCGATCC-3' is mutated to 5'-TGCAATCC-3'.This is an
example of which type of mutation? - CORRECT ANSWER - Transition
The following DNA sequence 5'-TGCGATCC-3' is mutated to produce 5'-TGCGATAC-3'.This is
an example of which type of mutation? - CORRECT ANSWER - Transversion
Which of the following chemical mutagen is most likely to cause a frameshift mutation? -
CORRECT ANSWER - Proflavin
nitrous acid and
5-bromouracil cause transition mutations
Which of the following pieces of evidence/statements supports the concept that "Mutation is
non-adaptive"? - CORRECT ANSWER - NOT A small proportion of colonies exposed to
antibiotic will survive due to the presence of an antibiotic resistance mutation.
, The base analog 5-Bromouracil is capable of base pairing with which of the following bases? -
CORRECT ANSWER - i) Adenine
ii) Guanine
bonds to A and G and induces transition mutations
If the following fragment of a non-template (coding) DNA strand 5'-ATGCCAGAG-3' was
mutated to produce 5'-ATGCCATAG-3' it would result in which of the following? - CORRECT
ANSWER - a non-sense mutation
GAG -> UAG (stop)
Which of the following is an example of a tri-nucleotide repeat expansion disease? - CORRECT
ANSWER - Huntington's disease
Which of the following is NOT a factor which influences the rate of spontaneous mutation? -
CORRECT ANSWER - environmental / selective pressure
Acridine dyes are most likely to cause which type of mutation? - CORRECT ANSWER -
Frameshifts
The deletion of 2 consecutive nucleotides in a DNA sequence would result in which type of
mutation? - CORRECT ANSWER - Frameshift mutation
deletion of 1+ bases
Because tautomeric shifts are transient, they do not cause permanent mutations. - CORRECT
ANSWER - False
Tautomeric shifts typically result in which type of mutation? - CORRECT ANSWER - more
than 1 of the above
