Tietz Fundamentals Of
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CLINICAL CHEMISTRY AND
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MOLECULAR DIAGNOSTICS z
7th Edition By Carl A. Burtis
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TEST BANK z
,TietzzFundamentalszofzClinicalzChemistryzandzMolecularzDiagnosticsz7thz EditionzTestzBank
Tablezofzcontents:
I.zPrincipleszOfzLaboratoryzMedicine
Chapterz1.zClinicalzChemistry,zMolecularzDiagnostics,zandzLaboratoryzMedicine
Chapterz2.zSelectionzandzAnalyticalzEvaluationzofzMethodsz—zWithzStatisticalzTechniques
Chapterz3.zClinicalzEvaluationzofzMethods
Chapterz4.zEvidence-BasedzLaboratoryzMedicine
Chapterz5.zEstablishmentzandzUsezofzReferencezValues
Chapterz6.zSpecimenzCollection,zProcessing,zandzOtherzPreanalyticalzVariables
Chapterz7.zQualityzManagement
II.zAnalyticalzTechniqueszAndzInstrumentation
Chapterz8.zPrincipleszofzBasiczTechniqueszandzLaboratoryzSafety
Chapterz9.zOpticalzTechniques
Chapterz10.zElectrochemistryzandzChemicalzSensors
Chapterz11.zElectrophoresis
Chapterz12.zChromatography
Chapterz13.zMasszSpectrometry
Chapterz14.zEnzymezandz RatezAnalyses
Chapterz15.zImmunochemicalzTechniques
Chapterz16zAutomation
Chapterz17.zPoint-of-CarezInstrumentation
III.z Analytes
Chapterz18.zAminozAcids,zPeptides,zandzProteins
Chapterz19.zSerumzEnzymes
Chapterz20.zTumorzMarkerszandzCancerzGenes
Chapterz21.zKidneyzFunctionzTestsz—zCreatinine,zGFR,zUrea,zandzUriczAcid
Chapterz22.zCarbohydrates
Chapterz23.zLipids,zLipoproteins,zApolipoproteins,zandzOtherzCardiaczRiskzFactors
Chapterz24.zElectrolyteszandzBloodzGases
Chapterz25.zHormones
Chapterz26.z CatecholamineszandzSerotonin
Chapterz27.z Vitamins,zTracezElements,zNutritionalzAssessment
Chapterz28.zHemoglobin,zIron,zandzBilirubin
Chapterz29.zPorphyrinszandzPorphyrias
Chapterz30.zTherapeuticzDrugszandzTheirzManagement
Chapterz31.zClinicalzToxicology
Chapterz32.z ToxiczMetals
IV.z Pathophysiology
Chapterz33.zDiabetes
,Chapterz34.z CardiovascularzDisease
Chapterz35.zKidneyzDisease
Chapterz36.z PhysiologyzandzDisorderszofzWater,zElectrolyte,zandzAcid-BasezMetabolism
Chapterz37.z LiverzDisease
Chapterz38.z GastrointestinalzandzPancreaticzDiseases
Chapterz39.z DisorderszofzBonezandzMineralzMetabolism
Chapterz40.z DisorderszofzthezPituitaryzGland
Chapterz41.z DisorderszofzthezAdrenalzCortex
Chapterz42.z ThyroidzDisorders
Chapterz43.z Reproduction-RelatedzDisorders
Chapterz44.z PregnancyzandzPrenatalzTesting
Chapterz45.z NewbornzScreeningzandz InbornzErrorszofzMetabolism
Chapterz46.zPharmacogenetics
V.z MolecularzDiagnostics
Chapterz47.zPrincipleszofzMolecularzBiology
Chapterz48.zNucleiczAcidzTechniqueszandzApplications
Chapterz49.zGenomeszandzNucleiczAcidzAlterations
, TietzzFundamentalszofzClinicalzChemistryzandzMolecularDiagnostics,z7ezBurtiszTestzBank
Chapterz01:zClinicalzChemistry,zMolecularzDiagnostics,zandzLaboratoryzMedicineTestzBank
MULTIPLEzCHOICE
1. Anzindividualzworkingzinzazclinicalzchemistryzlaboratoryziszmarriedztozazsaleszrepresentativezw
hozworkszforzazcompanyzthatzsellszchemistryzlaboratoryzsupplies.zWhenzthezlaboratoryzmanager
zrequestszazlistzofzneededzsupplies,zcostzofzsupplies,zandzvendors,zthiszindividualzonlyzrecommen
dszthezspouse’szcompanyzaszthezvendor.zThisziszconsideredztozbeza(n):
a. accountingzissue.
b. possiblezconflictzofzinterest.
c. maintenancezofzconfidentialityzissue.
d. problemzwithzresourcezallocation.
ANS:z B
Concernzhaszbeenzraisedzoverzthezinterrelationshipszbetweenzpractitionerszinzthezmedicalzfieldzand
zcommercialzsupplierszofzdrugs,zdevices,zequipment,zetc.,ztozthezmedicalzprofession.
Similarly,zrelationshipszhavezbeenzscrutinizedzbetweenzclinicalzlaboratorianszandzmanufacturersz
andzproviderszofzdiagnosticzequipmentzandzsupplies.zThesezconcernszledzthezNationalzInstituteszo
fzHealthz(NIH)zinz1995ztozrequirezofficialzinstitutionalzreviewzofzfinancialzdisclosurezbyzresearch
erszandzmanagementzofzsituationszinzwhichzdisclosurezindicateszpotentialzconflictszofzinterest.
DIF: 1 REF:z Pagez4-5 OBJ:z 6z|z7
2. Azpatientzvisitszherzphysicianzstatingzthatzherzprescribedzpainkillerzisznotzworkingztozreducezth
ezpainzfollowingzherzrecentzsurgery.zAzfriendzofzthezpatientzclaimszthatzthezsamezpainkillerz“wo
rkedzwonders”ztozreducezherzpainzafterzthezsamezsurgery.zThezphysicianzstateszthatzthezdiffere
ncezinzthezeffectzofzthezdrugzmightzbezcausedzby
,zwhichziszstudiedzinzpharmacoge
netics.
a. epidemiology
b. anzinheritedzdisease
c. azconflictzofzinterest
d. azgeneticzvariationzinzdrug-metabolizingzenzymes
ANS:z D
Pharmacogeneticsziszthezstudyzofzthezgeneticzvariationzofzdrugzmetabolismzbetweenzindividu
als.
DIF: 1 REF:z z Pagez3 OBJ:z 1
3. Johnzworkszinzazmolecularzdiagnosticszlaboratoryzandzreceiveszazbloodzsamplezthatzhaszthezna
mezofzazclosezfriendzprintedzonzthezbar-
codedzlabel.zThezgeneticztestzthatziszorderedzonzthezfriend’szsamplezwouldzprovidezdiagnosticzi
nformationzaboutzazdisorderzthatzhaszazpoorzprognosis,zandztheztestziszusuallyzperformedzbyzJo
hn.zHezaskszazfellowzemployeeztozanalyzezthezsamplezforzhimzandznotzdivulgezthezresults.zThisz
ethicalzissuezconcerns:
a. confidentialityzofzpatientzgeneticzandzmedicalzinformation.
b. azconflictzofzinterest.
c. resourcezallocation.
d. diagnosticzaccuracy.