NURS 5315 UTA Exam 2
-Osis or -philia - ANS-Elevated depend of blood cells
-penia - ANS-Low be counted of blood cells
4th technology immunoassay - ANS-"gold trendy"
can test 10 days publish exposure
can result negative, fantastic with HIV antibody, or wonderful with out HIV antibody
Acute Lymphocytic Leukemia (ALL) - ANS-Marked by way of >30% lymphoblasts in blood or
marrow
Most not unusual in kids
Survival fee decreases with age
CM: fever, pallor, bleeding, fatigue, lymphadenopathy, infection, joint pain, splenomegaly,
hepatomegaly, night time sweats, weight loss, anemia, thrombocytopenia, petechiae,
ecchymosis
Acute Myelogenous Leukemia (AML) - ANS-Marked with the aid of proliferation of immature
myeloid cells, decreased apoptosis, and shortage of cellular differentiation
Most common in adults
Remission is inversely associated with age
CM: fever, pallor, bleeding, fatigue, lymphadenopathy, contamination, joint ache,
splenomegaly, hepatomegaly, night sweats, weight loss, anemia, thrombocytopenia,
petechiae, ecchymosis
Alloimmunity and instance of hypersensitive reaction - ANS-When an individuals immune
device reacts towards antigens at the tissues of different members of the equal species
Blood transfusions- causes clumping and lysis of RBC- fever, nausea, chills, low lower back
pain, darkish urine, hives, itching, SOB
Rh incompatibility- hemolytic sickness of new child with jaundice, deliver Rhogam inside 72
hours of start (Rh- mother with Rh+ child)
Antiretroviral medicinal drugs - ANS-Used to impede viral replication of HIV virus, are
available 6 classes
1. Nucleoside reverse transcriptase inhibitors
2. Non-nucleoside reverse transcriptase inhibitors
3. Protease inhibitors
four. CCR5 inhibitors- inhibits binding to CCR3
five. Fusion inhibitor- inhibits fusion between HIV and cell membrane
6. Integrate inhibitor- inhibits viral integrate enzyme
Arachidonic pathway cause - ANS-Synthesis of prostaglandins
ASA - ANS-Blocks COX1 and COX2, also inhibits Thromboxane A2 and prostaglandins
Atopic problems - ANS-Genetic Type 1 allergic reaction, asthma, hay fever, eczema,
urticaria
Autoimmunity and instance of allergic reaction - ANS-A breakdown of tolerance wherein the
bodies immune device starts offevolved to understand self-antigens as foreign.
Graves Disease- autoantibodies shape towards thyroid cells- bind to thyroid cells and mimic
motion of TSH, will increase secretion of thyroxine
, Myasthenia Gravis- autoantibodies in opposition to acetylcholine bind to the put up synaptic
receptors and inhibit synaptic transmission of acetylcholine. Leads to muscle weak spot and
paralysis (mind to floor)
Guillain-Barre' syndrome- antibodies bind with myelin sheath of the peripheral fearful
machine, triggering the immune reaction. Causes demyelination of the peripheral nerves and
a hastily modern, ascending paralysis (ground to brain)
Basophilia- definition and causes - ANS-Increased # of basophils
From allergies
reasons of thrombus - ANS-Triad of Virchow- damage to blood vessels, abnormality in blood
waft, hypercoagulability
a few medications increase risks
Chemotactic factors - ANS-Biochemical substance that attracts leukocyte to the website
online of irritation
Chronic leukemia - ANS-Gradual onset, cells seem everyday however do not feature
appropriately and accumulate
Chronic Lymphocytic Leukemia (CLL) - ANS-Malignant transformation of B-lymphocytes
Increased incidence over forty
Survival 10yrs or longer
CM: suppression of humoral immunity, improved infections
Chronic Myelogenous Leukemia (CML) - ANS-Presence of Philadelphia chromosome
Increased prevalence over 40
Bone marrow transplant can be curative
CM: splenomegal (maximum not unusual), hepatomegaly, hyperuricemia, contamination,
fever, weight reduction
medical implications of influenza - ANS-prevention is prime- vaccinate at 6+ months, annual
identified via fast swab
treat with antivirals- Tamiflu
Clinical implications of measeles - ANS-One of maximum contagious infectious illnesses,
lasts 7-10 days
Educate mother and father on significance of vaccination
Immune globulin may be administered within 6 days of publicity
Can be fatal for HIV sufferers
Immunocompromised may have no rash
Need serologic checking out in step with CDC
Tx is supportive- rehydration, Vit A
medical manifestations of influenza - ANS-fever, sore throat, myalgias, headache, nasal
discharge, weak point and severe fatigue, cough and different breathing symptoms,
tachycardia, pink, watery eyes, pharyngitis
scientific manifestations of measles - ANS-fever >104, lasts 4-7 days, malaise, anorexia,
3c's- conjunctivitis, cough, coryza (irritation of mucous membrane of nostril), photophobia,
periorbital edema, myalgias, Koplik spots (bluish-grey specks on pink base, on buccal
mucosa), rash- begins at hairline, spreads in forty eight hours
CM of Hodgkin's Lymphoma - ANS-Large painless lump/mass- normally on neck,
eosinophilia, fever, weight reduction, night sweats, pruritus, adenopathy, thrombocytosis,
leukocytosis, mediastinal or abdominal mass
CM of Non-Hodgkin's Lymphoma - ANS-Generalized lymphadenopathy
Late ranges bring fever, night time sweats, weight reduction
CMV- cytomegalovirus - ANS-herpes virus
-Osis or -philia - ANS-Elevated depend of blood cells
-penia - ANS-Low be counted of blood cells
4th technology immunoassay - ANS-"gold trendy"
can test 10 days publish exposure
can result negative, fantastic with HIV antibody, or wonderful with out HIV antibody
Acute Lymphocytic Leukemia (ALL) - ANS-Marked by way of >30% lymphoblasts in blood or
marrow
Most not unusual in kids
Survival fee decreases with age
CM: fever, pallor, bleeding, fatigue, lymphadenopathy, infection, joint pain, splenomegaly,
hepatomegaly, night time sweats, weight loss, anemia, thrombocytopenia, petechiae,
ecchymosis
Acute Myelogenous Leukemia (AML) - ANS-Marked with the aid of proliferation of immature
myeloid cells, decreased apoptosis, and shortage of cellular differentiation
Most common in adults
Remission is inversely associated with age
CM: fever, pallor, bleeding, fatigue, lymphadenopathy, contamination, joint ache,
splenomegaly, hepatomegaly, night sweats, weight loss, anemia, thrombocytopenia,
petechiae, ecchymosis
Alloimmunity and instance of hypersensitive reaction - ANS-When an individuals immune
device reacts towards antigens at the tissues of different members of the equal species
Blood transfusions- causes clumping and lysis of RBC- fever, nausea, chills, low lower back
pain, darkish urine, hives, itching, SOB
Rh incompatibility- hemolytic sickness of new child with jaundice, deliver Rhogam inside 72
hours of start (Rh- mother with Rh+ child)
Antiretroviral medicinal drugs - ANS-Used to impede viral replication of HIV virus, are
available 6 classes
1. Nucleoside reverse transcriptase inhibitors
2. Non-nucleoside reverse transcriptase inhibitors
3. Protease inhibitors
four. CCR5 inhibitors- inhibits binding to CCR3
five. Fusion inhibitor- inhibits fusion between HIV and cell membrane
6. Integrate inhibitor- inhibits viral integrate enzyme
Arachidonic pathway cause - ANS-Synthesis of prostaglandins
ASA - ANS-Blocks COX1 and COX2, also inhibits Thromboxane A2 and prostaglandins
Atopic problems - ANS-Genetic Type 1 allergic reaction, asthma, hay fever, eczema,
urticaria
Autoimmunity and instance of allergic reaction - ANS-A breakdown of tolerance wherein the
bodies immune device starts offevolved to understand self-antigens as foreign.
Graves Disease- autoantibodies shape towards thyroid cells- bind to thyroid cells and mimic
motion of TSH, will increase secretion of thyroxine
, Myasthenia Gravis- autoantibodies in opposition to acetylcholine bind to the put up synaptic
receptors and inhibit synaptic transmission of acetylcholine. Leads to muscle weak spot and
paralysis (mind to floor)
Guillain-Barre' syndrome- antibodies bind with myelin sheath of the peripheral fearful
machine, triggering the immune reaction. Causes demyelination of the peripheral nerves and
a hastily modern, ascending paralysis (ground to brain)
Basophilia- definition and causes - ANS-Increased # of basophils
From allergies
reasons of thrombus - ANS-Triad of Virchow- damage to blood vessels, abnormality in blood
waft, hypercoagulability
a few medications increase risks
Chemotactic factors - ANS-Biochemical substance that attracts leukocyte to the website
online of irritation
Chronic leukemia - ANS-Gradual onset, cells seem everyday however do not feature
appropriately and accumulate
Chronic Lymphocytic Leukemia (CLL) - ANS-Malignant transformation of B-lymphocytes
Increased incidence over forty
Survival 10yrs or longer
CM: suppression of humoral immunity, improved infections
Chronic Myelogenous Leukemia (CML) - ANS-Presence of Philadelphia chromosome
Increased prevalence over 40
Bone marrow transplant can be curative
CM: splenomegal (maximum not unusual), hepatomegaly, hyperuricemia, contamination,
fever, weight reduction
medical implications of influenza - ANS-prevention is prime- vaccinate at 6+ months, annual
identified via fast swab
treat with antivirals- Tamiflu
Clinical implications of measeles - ANS-One of maximum contagious infectious illnesses,
lasts 7-10 days
Educate mother and father on significance of vaccination
Immune globulin may be administered within 6 days of publicity
Can be fatal for HIV sufferers
Immunocompromised may have no rash
Need serologic checking out in step with CDC
Tx is supportive- rehydration, Vit A
medical manifestations of influenza - ANS-fever, sore throat, myalgias, headache, nasal
discharge, weak point and severe fatigue, cough and different breathing symptoms,
tachycardia, pink, watery eyes, pharyngitis
scientific manifestations of measles - ANS-fever >104, lasts 4-7 days, malaise, anorexia,
3c's- conjunctivitis, cough, coryza (irritation of mucous membrane of nostril), photophobia,
periorbital edema, myalgias, Koplik spots (bluish-grey specks on pink base, on buccal
mucosa), rash- begins at hairline, spreads in forty eight hours
CM of Hodgkin's Lymphoma - ANS-Large painless lump/mass- normally on neck,
eosinophilia, fever, weight reduction, night sweats, pruritus, adenopathy, thrombocytosis,
leukocytosis, mediastinal or abdominal mass
CM of Non-Hodgkin's Lymphoma - ANS-Generalized lymphadenopathy
Late ranges bring fever, night time sweats, weight reduction
CMV- cytomegalovirus - ANS-herpes virus
