,TEST BANK FOR CLINICAL IMMUNOLOGY AND
SEROLOGY A LABORATORY PERSPECTIVE, 4TH EDITION,
CHRISTINE DORRESTEYN STEVENS, LINDA E. MILLER
COMPLETE CHAPTERS
Chapter 1. Introduction to Immunity and the Immune System
Multiple Choice
1. Eosinophils are involved in the immune response against:
A. viruses.
B. intracellular bacteria.
C. parasites that cannot be phagocytized.
D. extracellular bacteria.
ANS: C
2. Which of the following are components of both innate and adaptive
immune responses? A. Immunoglobulins
B. T helper cells
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,C. Macrophages
D. B cells
ANS: C
3. The process by which leukocytes are attracted to a specific area by
chemical messengers is called: A. diapedesis.
B. degranulation.
C. chemotaxis.
D. opsonization.
ANS: C
4. Which of the following is a characteristic of natural killer cells? A.
They mature in the thymus.
B. They are smaller than B and T cells.
C. They are a type of lymphocyte.
D. They are part of the adaptive immune system.
ANS: C
5. Which of the following best describes diapedesis?
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,A. Movement toward increasing concentrations of a cytokine
B. Attachment of immunoglobulin to target cells
C. Movement through blood vessel walls as cells exit the circulation
D. Engulfment of target cells
ANS: C
6. The most effective phagocytic and antigen-presenting cell is the: A.
neutrophil.
B. monocyte.
C. dendritic cell.
D. macrophage.
ANS: C
7. Which of the following is characteristic of natural immunity? A. It
involves memory.
B. T lymphocytes play a major role.
C. It involves specificity.
D. Mechanisms are always present and fully functional.
ANS: D
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,8. All of the following cells are considered part of natural immunity
EXCEPT: A. eosinophils.
B. B lymphocytes.
C. monocytes.
D. neutrophils.
ANS: B
9. Where does the specific immune response to a foreign antigen mainly
occur?
A. Lymph nodes
B. Blood
C. Bone marrow
D. Skin
ANS: A
10. Which white cell in the peripheral blood migrates into tissue to
become a macrophage? A. Eosinophil
B. Basophil
C. Neutrophil
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,D. Monocyte
ANS: D
11. A white blood cell that is 16 to 18 micrometers in diameter, has a
horseshoe-shaped nucleus, and is capable of phagocytosis is a: A.
neutrophil.
B. eosinophil.
C. basophil.
D. monocyte.
ANS: D
12. Pasteur's discovery that older bacterial cultures would not cause
disease in chickens but would protect them from subsequent infection
with more virulent strains is an example of: A. attenuated vaccine.
B. natural immunity.
C. passive immunity.
D. cross-immunity.
ANS: A
13. Antibodies are secreted by: A. plasma cells.
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,B. B cells.
C. T cells.
D. dendritic cells.
ANS: A
14. Which of the following is characteristic of mucosal-associated
lymphoid tissue? A. It is one of the primary lymphoid organs.
B. It clears pathogens from the bloodstream.
C. It includes the tonsils and the appendix.
D. It includes the liver and spleen.
ANS: C
15. Acquired (adaptive) immunity can be characterized as: A.
nonspecifically activated.
B. immediately responsive.
C. neutrophil dependent.
D. involving memory.
ANS: D
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,16. Which of the following is NOT a characteristic of neutrophils?
A. Congregate in the marginating pool in blood vessels
B. Capable of diapedesis
C. Granules that become bright orange with Wright stain
D. Segmented nucleus
ANS: C
17. The function of NK cells is to: A. produce antibody.
B. phagocytize bacteria.
C. present antigen to T cells.
D. kill target cells such as tumor and virally infected cells.
ANS: D
18. All of the following are involved in adaptive immunity EXCEPT: A.
memory.
B. lymphocytes.
C. specificity.
D. neutrophils.
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,ANS: D
19. Which of the following is NOT a characteristic of a lymph node?
A. Filters interstitial fluid draining from tissues
B. Colonized with T and B cells
C. Between 1 and 25 mm in size
D. Considered a primary or central lymphoid organ
ANS: D
20. All of the following are considered part of natural immunity
EXCEPT: A. eosinophils.
B. lymphocytes.
C. acute-phase reactants.
D. neutrophils.
ANS: B
21. Macrophages that migrate to the liver are called: A. alveolar
macrophages.
B. histiocytes.
C. microglial cells.
D. Kupffer cells.
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
, ANS: D
22. Innate immunity can be characterized as: A. specific.
B. slow to respond.
C. dependent upon neutrophils and macrophages.
D. involving memory.
ANS: C
23. The ability to resist infection through normally present body
functions best characterizes: A. autoimmunity.
B. natural immunity.
C. acquired immunity.
D. alloimmunity.
ANS: B
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
SEROLOGY A LABORATORY PERSPECTIVE, 4TH EDITION,
CHRISTINE DORRESTEYN STEVENS, LINDA E. MILLER
COMPLETE CHAPTERS
Chapter 1. Introduction to Immunity and the Immune System
Multiple Choice
1. Eosinophils are involved in the immune response against:
A. viruses.
B. intracellular bacteria.
C. parasites that cannot be phagocytized.
D. extracellular bacteria.
ANS: C
2. Which of the following are components of both innate and adaptive
immune responses? A. Immunoglobulins
B. T helper cells
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,C. Macrophages
D. B cells
ANS: C
3. The process by which leukocytes are attracted to a specific area by
chemical messengers is called: A. diapedesis.
B. degranulation.
C. chemotaxis.
D. opsonization.
ANS: C
4. Which of the following is a characteristic of natural killer cells? A.
They mature in the thymus.
B. They are smaller than B and T cells.
C. They are a type of lymphocyte.
D. They are part of the adaptive immune system.
ANS: C
5. Which of the following best describes diapedesis?
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,A. Movement toward increasing concentrations of a cytokine
B. Attachment of immunoglobulin to target cells
C. Movement through blood vessel walls as cells exit the circulation
D. Engulfment of target cells
ANS: C
6. The most effective phagocytic and antigen-presenting cell is the: A.
neutrophil.
B. monocyte.
C. dendritic cell.
D. macrophage.
ANS: C
7. Which of the following is characteristic of natural immunity? A. It
involves memory.
B. T lymphocytes play a major role.
C. It involves specificity.
D. Mechanisms are always present and fully functional.
ANS: D
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,8. All of the following cells are considered part of natural immunity
EXCEPT: A. eosinophils.
B. B lymphocytes.
C. monocytes.
D. neutrophils.
ANS: B
9. Where does the specific immune response to a foreign antigen mainly
occur?
A. Lymph nodes
B. Blood
C. Bone marrow
D. Skin
ANS: A
10. Which white cell in the peripheral blood migrates into tissue to
become a macrophage? A. Eosinophil
B. Basophil
C. Neutrophil
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,D. Monocyte
ANS: D
11. A white blood cell that is 16 to 18 micrometers in diameter, has a
horseshoe-shaped nucleus, and is capable of phagocytosis is a: A.
neutrophil.
B. eosinophil.
C. basophil.
D. monocyte.
ANS: D
12. Pasteur's discovery that older bacterial cultures would not cause
disease in chickens but would protect them from subsequent infection
with more virulent strains is an example of: A. attenuated vaccine.
B. natural immunity.
C. passive immunity.
D. cross-immunity.
ANS: A
13. Antibodies are secreted by: A. plasma cells.
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,B. B cells.
C. T cells.
D. dendritic cells.
ANS: A
14. Which of the following is characteristic of mucosal-associated
lymphoid tissue? A. It is one of the primary lymphoid organs.
B. It clears pathogens from the bloodstream.
C. It includes the tonsils and the appendix.
D. It includes the liver and spleen.
ANS: C
15. Acquired (adaptive) immunity can be characterized as: A.
nonspecifically activated.
B. immediately responsive.
C. neutrophil dependent.
D. involving memory.
ANS: D
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,16. Which of the following is NOT a characteristic of neutrophils?
A. Congregate in the marginating pool in blood vessels
B. Capable of diapedesis
C. Granules that become bright orange with Wright stain
D. Segmented nucleus
ANS: C
17. The function of NK cells is to: A. produce antibody.
B. phagocytize bacteria.
C. present antigen to T cells.
D. kill target cells such as tumor and virally infected cells.
ANS: D
18. All of the following are involved in adaptive immunity EXCEPT: A.
memory.
B. lymphocytes.
C. specificity.
D. neutrophils.
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,ANS: D
19. Which of the following is NOT a characteristic of a lymph node?
A. Filters interstitial fluid draining from tissues
B. Colonized with T and B cells
C. Between 1 and 25 mm in size
D. Considered a primary or central lymphoid organ
ANS: D
20. All of the following are considered part of natural immunity
EXCEPT: A. eosinophils.
B. lymphocytes.
C. acute-phase reactants.
D. neutrophils.
ANS: B
21. Macrophages that migrate to the liver are called: A. alveolar
macrophages.
B. histiocytes.
C. microglial cells.
D. Kupffer cells.
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
, ANS: D
22. Innate immunity can be characterized as: A. specific.
B. slow to respond.
C. dependent upon neutrophils and macrophages.
D. involving memory.
ANS: C
23. The ability to resist infection through normally present body
functions best characterizes: A. autoimmunity.
B. natural immunity.
C. acquired immunity.
D. alloimmunity.
ANS: B
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
