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1. What is the term for the period of endocrinologic, somatic, and transitory psychological
changes that occur around the time of menopause?
A) Perimenopause
B) Climacteric phase
C) Menstrual transition
D) Postmenopause
Answer: B) Climacteric phase
Rationale: The climacteric phase encompasses the various physiological and psychological
changes that women experience during the transition to menopause.
2. If a woman's Last Menstrual Period (LMP) occurs before age 45, what is this condition
called?
A) Primary ovarian insufficiency
B) Early menopause
C) Late menopause
D) Menopause transition
Answer: B) Early menopause
Rationale: Early menopause refers to menopause that occurs before the age of 45, distinguishing
it from typical menopausal onset.
3. What term describes menopause that occurs before the age of 40?
,A) Premature menopause
B) Early menopause
C) Primary ovarian insufficiency
D) Late menopause
Answer: C) Primary ovarian insufficiency
Rationale: Primary ovarian insufficiency (POI) is the term used when menopause occurs before
the age of 40, indicating a significant decline in ovarian function.
4. A persistent difference of 7 days or more in the length of consecutive menstrual cycles is
indicative of which stage?
A) Late menopause transition (stage -1)
B) Early menopause transition (stage -2)
C) Perimenopause
D) Postmenopause
Answer: B) Early menopause transition (stage -2)
Rationale: A persistent variation of 7 days or more between consecutive menstrual cycles
signifies the early menopause transition, specifically stage -2.
5. What is characterized by 60 or more consecutive days of amenorrhea?
A) Early menopause transition (stage -2)
B) Late menopause transition (stage -1)
C) Perimenopause
D) Primary ovarian insufficiency
Answer: B) Late menopause transition (stage -1)
Rationale: Late menopause transition, or stage -1, is marked by extended periods of amenorrhea,
typically 60 days or more.
,6. Which event explains why some perimenopausal women have elevated estrogen levels at
times?
A) Elevated LH levels
B) Luteal out of phase event (LOOP)
C) Increased FSH sensitivity
D) Enhanced follicular recruitment
Answer: B) Luteal out of phase event (LOOP)
Rationale: The luteal out of phase event (LOOP) describes a scenario where elevated FSH levels
recruit a second follicle, leading to temporary rises in estradiol that cause elevated estrogen
levels during the menopause transition.
7. Obese women are at higher risk of endometrial cancer due to which of the following
reasons?
A) Lower premenopause estradiol levels
B) Higher postmenopause estradiol levels
C) Elevated progesterone levels
D) Reduced androgen levels
Answer: B) Higher postmenopause estradiol levels
Rationale: Obese women tend to have higher estradiol levels postmenopause due to increased
aromatization in adipose tissue, which elevates the risk of endometrial hyperplasia and cancer.
8. Which ethnic groups have lower estradiol levels compared to white, black, and Hispanic
women?
A) Chinese and Japanese women
B) African and Hispanic women
, C) Indian and Korean women
D) Middle Eastern women
Answer: A) Chinese and Japanese women
Rationale: Studies have shown that Chinese and Japanese women generally have lower estradiol
levels compared to their white, black, and Hispanic counterparts.
9. What stage is characterized by 5-8 years after the Final Menstrual Period (FMP), where
somatic aging predominates and genitourinary symptoms increase?
A) Stage +1a
B) Stage +1b
C) Stage +1c
D) Stage +2
Answer: D) Stage +2
Rationale: Stage +2 occurs 5-8 years post-FMP, marked by predominant somatic aging and an
increase in genitourinary symptoms.
10. During the early postmenopause stage (2 years after FMP), which of the following
hormonal changes occur?
A) Decreased FSH and increased estradiol
B) Elevated FSH and decreased estradiol
C) Elevated LH and increased progesterone
D) Decreased LH and increased FSH
Answer: B) Elevated FSH and decreased estradiol
Rationale: In the early postmenopause stage, FSH levels remain elevated while estradiol levels
decrease, reflecting the diminished ovarian function.