TEST BANK FOR Basic and Clinical Pharmacology 14th Edition Katzung Trevor

Basic and Clinical Pharmacology 14th Edition Katzung Trevor Test Bank
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Basic and Clinical Pharmacology 14th Edition Katzung Trevor Test Bank
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Chapterb1.bIntroduction:bThebNaturebofbDrugsb&bDrugbDevelopmentb&bRegulation


1.
Abnursebworkingbinbradiologybadministersbiodinebtobabpatientbwhobisbhavingb
abcomputedbtomographyb(CT)bscan.bThebnursebworkingbonbtheboncologybunitba
dministersbchemotherapybtobpatientsbwhobhavebcancer.bAtbthebPublicbHealthbD
epartment,babnursebadministersbabmeasles-mumps-
rubellab(MMR)bvaccinebtobab14-month-
oldbchildbasbabroutinebimmunization.bWhichbbranchbofbpharmacologybbestbdesc
ribesbthebactionsbofballbthreeb nurses?
A) Pharmacoeconomics

B) Pharmacotherapeutics

C) Pharmacodynamics

D) Pharmacokinetics

Ans: B

Feedback:

Pharmacologybisbthebstudybofbthebbiologicbeffectsbofbchemicals.bNursesbarebinv
olvedbwithbclinicalbpharmacologyborbpharmacotherapeutics,bwhichbisbabbranchb
ofbpharmacologybthatbdealsbwithbthebusesbofbdrugsbtobtreat,bprevent,bandbdiagno
sebdisease.bThebradiologybnursebisbadministeringbabdrugbtobhelpbdiagnosebabdise
ase.bTheboncologybnursebisbadministeringbabdrugbtobhelpbtreatbabdisease.bPharma
coeconomicsbincludesbanybcostsbinvolvedbinbdrugb therapy.
Pharmacodynamicsbinvolvesbhowbabdrugbaffectsbthebbodybandb
pharmacokineticsbisbhowbthebbodybactsbonbthebbody.


2.
Abphysicianbhasborderedbintramuscularb(IM)binjectionsbofbmorphine,babnarc
otic,beveryb4bhoursbasbneededbforbpainbinbabmotorbvehiclebaccidentbvictim.bTheb
nursebisbawarebthisbdrugbhasbabhighbabusebpotential.bUnderbwhatbcategorybwoul
dbmorphinebbebclassified?
A) SchedulebI


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B) SchedulebII




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C) SchedulebIII

D) SchedulebIV

Ans: B

Feedback:

NarcoticsbwithbabhighbabusebpotentialbarebclassifiedbasbSchedulebIIbdrugsbbeca
usebofbseverebdependencebliability.bSchedulebIbdrugsbhavebhighbabusebpotentia
lbandbnobacceptedbmedicalbuse.bSchedulebIIIbdrugsbhavebablesserbabusebpotenti
albthanbIIbandbanbacceptedbmedicalbuse.bSchedulebIVbdrugsbhaveblowbabusebpot
entialbandblimitedbdependenceb liability.


3.
WhenbinvolvedbinbphasebIIIbdrugbevaluationbstudies,bwhatbresponsibiliti
esbwouldbthebnursebhave?
A) Workingbwithbanimalsbwhobarebgivenbexperimentalb drugs

B) Choosingbappropriatebpatientsbtobbebinvolvedbinbthebdrugb study

C) Monitoringbandbobservingbpatientsbcloselybforbadverseb effects

D) Conductingbresearchbtobdeterminebeffectivenessbofbtheb drug

Ans: C

Feedback:

PhasebIIIbstudiesbinvolvebusebofbabdrugbinbabvastbclinicalbpopulationbinbwhichbp
atientsbarebaskedbtobrecordbanybsymptomsbtheybexperiencebwhilebtakingbthebdr
ugs.bNursesbmaybbebresponsiblebforbhelpingbcollectbandbanalyzebthebinformati
onbtobbebsharedbwithbthebFoodbandbDrugbAdministrationb(FDA)bbutbwouldbnotb
conductbresearchbindependentlybbecausebnursesbdobnotbprescribebmedications
.bUsebofbanimalsbinbdrugbtestingbisbdonebinbthebpreclinicalbtrials.bSelectbpatient
sbwhobarebinvolvedbinbphasebIIbstudiesbtobparticipatebinbstudiesbwherebthebpart
icipantsbhavebthebdiseasebthebdrugbisbintendedbtobtreat.bThesebpatientsbarebmon
itoredbcloselybforbdrugbactionbandbadversebeffects.bPhasebIbstudiesbinvolvebhe
althybhumanbvolunteersbwhobarebusuallybpaidbforbtheirbparticipation.bNursesb
maybobservebforbadversebeffectsbandbtoxicity.


4.
Whatbconceptbisbconsideredbwhenbgenericbdrugsbarebsubstitutedbforbbra
ndbnamebdrugs?
A) Bioavailability

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B) Criticalbconcentration

C) Distribution

D) Half-life

Ans: A

Feedback:

Bioavailabilitybisbthebportionbofbabdosebofbabdrugbthatbreachesbthebsystemicbcir
culationbandbisbavailablebtobactbonbbodybcells.bBindersbusedbinbabgenericbdrugb
maybnotbbebthebsamebasbthosebusedbinbthebbrandbnamebdrug.bTherefore,bthebwa
ybthebbodybbreaksbdownbandbusesbthebdrugbmaybdiffer,bwhichbmaybeliminatebab
genericbdrugbsubstitution.bCriticalbconcentrationbisbthebamountbofbabdrugbthatbi
sbneededbtobcausebabtherapeuticbeffectbandbshouldbnotbdifferbbetweenbgenericba
ndbbrandbnamebmedications.bDistributionbisbthebphasebofbpharmacokinetics,bw
hichbinvolvesbthebmovementbofbabdrugbtobthebbodysbtissuesbandbisbthebsamebinb
genericbandbbrandbnamebdrugs.bAbdrugsbhalf-
lifebisbthebtimebitbtakesbforbthebamountbofbdrugbtobdecreasebtobhalfbthebpeakbleve
l,bwhichbshouldbnotbchangebwhenbsubstitutingbabgenericb medication.


5.
Abnursebisbassessingbthebpatientsbhomebmedicationbuse.bAfterblisteningbtobt
hebpatientblistbcurrentbmedications,bthebnursebasksbwhatbpriorityb question?
A) Dobyoubtakebanybgenericb medications?

B) Arebanybofbthesebmedicationsborphanb drugs?

C) Arebthesebmedicationsbsafebtobtakebduringb pregnancy?

D) Dobyoubtakebanybover-the-counterb medications?

Ans: D

Feedback:

Itbisbimportantbforbthebnursebtobspecificallybquestionbusebofbover-the-
counterbmedicationsbbecausebpatientsbmaybnotbconsiderbthembimportant.bTheb
patientbisbunlikelybtobknowbthebmeaningbofborphanbdrugsbunlessbtheybtoobarebh
ealthbcarebproviders.bSafetybduringbpregnancy,busebofbabgenericbmedication,bo
rbclassificationbofborphanbdrugsbarebthingsbthebpatientbwouldbbebunablebtobans
werbbutbcouldbbebfoundbinbreferencebbooksbifbthebnursebwishesbtobresearchbthe
m.




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