BASIC AND CLINICAL PHARMACOLOGY 15TH EDITION KA
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TZUNG TREVOR TEST BANK
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INCLUSIVEtOFtCHAPTERSt1-66tCOMPLETEtWITHtEXPLAINEDtANSWERS
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Basic and Clinical Pharmacology 15th Edition Katzung Trevor Test Bank
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Chaptert1.tIntroduction:tThetNaturetoftDrugst&tDrugtDevelopmentt&tRegulation
1.
Atnursetworkingtintradiologytadministerstiodinettotatpatienttwhotisthavingtatco
mputedttomographyt(CT)tscan.tThetnursetworkingtontthetoncologytunittadminist
erstchemotherapyttotpatientstwhothavetcancer.tAttthetPublictHealthtDepartment,t
atnursetadministerstatmeasles-mumps-rubellat(MMR)tvaccinettotat14-month-
oldtchildtastatroutinetimmunization.tWhichtbranchtoftpharmacologytbesttdescrib
estthetactionstoftalltthreet nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacologytistthetstudytoftthetbiologicteffectstoftchemicals.tNursestaretinvolv
edtwithtclinicaltpharmacologytortpharmacotherapeutics,twhichtistatbranchtoftph
armacologytthattdealstwithtthetusestoftdrugsttottreat,tprevent,tandtdiagnosetdisea
se.tThetradiologytnursetistadministeringtatdrugttothelptdiagnosetatdisease.tTheton
cologytnursetistadministeringtatdrugttothelpttreattatdisease.tPharmacoeconomicst
includestanytcoststinvolvedtintdrugttherapy.
Pharmacodynamicstinvolvesthowtatdrugtaffectstthetbodytandtpharmacokineticstis
thowtthetbodytactstontthetbody.
2.
WhentinvolvedtintphasetIIItdrugtevaluationtstudies,twhattr
esponsibilitiestwouldtthetnursethave?
A) Workingtwithtanimalstwhotaretgiventexperimentalt drugs
B) Choosingtappropriatetpatientsttotbetinvolvedtintthetdrugt study
C) Monitoringtandtobservingtpatientstcloselytfortadverset effects
D) Conductingtresearchttotdetermineteffectivenesstoftthet drug
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Ans: C
Feedback:
PhasetIIItstudiestinvolvetusetoftatdrugtintatvasttclinicaltpopulationtintwhichtpatien
tstaretaskedttotrecordtanytsymptomsttheytexperiencetwhilettakingtthetdrugs.tNur
sestmaytbetresponsibletforthelpingtcollecttandtanalyzetthetinformationttotbetshar
edtwithtthetFoodtandtDrugtAdministrationt(FDA)tbuttwouldtnottconducttresearc
htindependentlytbecausetnursestdotnottprescribetmedications.tUsetoftanimalstint
drugttestingtistdonetintthetpreclinicalttrials.tSelecttpatientstwhotaretinvolvedtintp
hasetIItstudiesttotparticipatetintstudiestwheretthetparticipantsthavetthetdiseasetthe
tdrugtistintendedttottreat.tThesetpatientstaretmonitoredtcloselytfortdrugtactiontan
dtadverseteffects.tPhasetItstudiestinvolvethealthythumantvolunteerstwhotaretusu
allytpaidtforttheirtparticipation.tNursestmaytobservetfortadverseteffectstandttoxic
ity.
3.
Atphysicianthastorderedtintramusculart(IM)tinjectionstoftmorphine,tatnarcoti
c,teveryt4thourstastneededtfortpaintintatmotortvehicletaccidenttvictim.tThetnurseti
stawaretthistdrugthastathightabusetpotential.tUndertwhattcategorytwouldtmorphi
netbetclassified?
A) ScheduletI
B) ScheduletII
C) ScheduletIII
D) ScheduletIV
Ans: B
Feedback:
NarcoticstwithtathightabusetpotentialtaretclassifiedtastScheduletIItdrugstbecaus
etoftseveretdependencetliability.tScheduletItdrugsthavethightabusetpotentialtan
dtnotacceptedtmedicaltuse.tScheduletIIItdrugsthavetatlessertabusetpotentialtthant
IItandtantacceptedtmedicaltuse.tScheduletIVtdrugsthavetlowtabusetpotentialtandt
limitedtdependencetliability.
4.
Whattconcepttistconsideredtwhentgenerictdrugstaretsubstitutedtfortbrandtn
ametdrugs?
A) Bioavailability
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