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,Chapter j1. jIntroduction: jThe jNature jof jDrugs j& jDrug jDevelopment j& jRegulation
1. A jnurse jworking jin jradiology jadministers jiodine jto ja jpatient jwho jis
jhaving ja jcomputed jtomography j(CT) jscan. jThe jnurse jworking jon jthe
joncology junit jadministers jchemotherapy jto jpatients jwho jhave jcancer. jAt
jthe jPublic jHealth jDepartment, ja jnurse jadministers ja jmeasles-mumps-
rubella j(MMR) jvaccine jto ja j14-month-old jchild jas ja jroutine jimmunization.
jWhich jbranch jof jpharmacology jbest jdescribes jthe jactions jof jall jthree
j nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology jis jthe jstudy jof jthe jbiologic jeffects jof jchemicals. jNurses jare
jinvolved jwith jclinical jpharmacology jor jpharmacotherapeutics, jwhich jis ja
jbranch jof jpharmacology jthat jdeals jwith jthe juses jof jdrugs jto jtreat,
jprevent, jand jdiagnose jdisease. jThe jradiology jnurse jis jadministering ja
jdrug jto jhelp jdiagnose ja jdisease. jThe joncology jnurse jis jadministering ja
jdrug jto jhelp jtreat ja jdisease. jPharmacoeconomics jincludes jany jcosts
jinvolved jin jdrug jtherapy.
Pharmacodynamics jinvolves jhow ja jdrug jaffects jthe jbody jand
jpharmacokinetics jis jhow jthe jbody jacts jon jthe jbody.
2. A jphysician jhas jordered jintramuscular j(IM) jinjections jof jmorphine, ja
jnarcotic, jevery j4 jhours jas jneeded jfor jpain jin ja jmotor jvehicle jaccident
jvictim. jThe jnurse jis jaware jthis jdrug jhas ja jhigh jabuse jpotential. jUnder
jwhat jcategory jwould jmorphine jbe jclassified?
A) Schedule jI
B) Schedule jII
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,C) Schedule jIII
D) Schedule jIV
Ans: B
Feedback:
Narcotics jwith ja jhigh jabuse jpotential jare jclassified jas jSchedule jII jdrugs
jbecause jof jsevere jdependence jliability. jSchedule jI jdrugs jhave jhigh
jabuse jpotential jand jno jaccepted jmedical juse. jSchedule jIII jdrugs jhave ja
jlesser jabuse jpotential jthan jII jand jan jaccepted jmedical juse. jSchedule jIV
jdrugs jhave jlow jabuse jpotential jand jlimited jdependence jliability.
3. When jinvolved jin jphase jIII jdrug jevaluation jstudies, jwhat
jresponsibilities jwould jthe jnurse jhave?
A) Working jwith janimals jwho jare jgiven jexperimental j drugs
B) Choosing jappropriate jpatients jto jbe jinvolved jin jthe jdrug j study
C) Monitoring jand jobserving jpatients jclosely jfor jadverse j effects
D) Conducting jresearch jto jdetermine jeffectiveness jof jthe j drug
Ans: C
Feedback:
Phase jIII jstudies jinvolve juse jof ja jdrug jin ja jvast jclinical jpopulation jin
jwhich jpatients jare jasked jto jrecord jany jsymptoms jthey jexperience jwhile
jtaking jthe jdrugs. jNurses jmay jbe jresponsible jfor jhelping jcollect jand
janalyze jthe jinformation jto jbe jshared jwith jthe jFood jand jDrug
jAdministration j(FDA) jbut jwould jnot jconduct jresearch jindependently
jbecause jnurses jdo jnot jprescribe jmedications. jUse jof janimals jin jdrug
jtesting jis jdone jin jthe jpreclinical jtrials. jSelect jpatients jwho jare jinvolved
jin jphase jII jstudies jto jparticipate jin jstudies jwhere jthe jparticipants jhave
jthe jdisease jthe jdrug jis jintended jto jtreat. jThese jpatients jare jmonitored
jclosely jfor jdrug jaction jand jadverse jeffects. jPhase jI jstudies jinvolve
jhealthy jhuman jvolunteers jwho jare jusually jpaid jfor jtheir jparticipation.
jNurses jmay jobserve jfor jadverse jeffects jand jtoxicity.
4. What jconcept jis jconsidered jwhen jgeneric jdrugs jare jsubstituted jfor
jbrand jname jdrugs?
A) Bioavailability
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, B) Critical jconcentration
C) Distribution
D) Half-life
Ans: A
Feedback:
Bioavailability jis jthe jportion jof ja jdose jof ja jdrug jthat jreaches jthe
jsystemic jcirculation jand jis javailable jto jact jon jbody jcells. jBinders jused
jin ja jgeneric jdrug jmay jnot jbe jthe jsame jas jthose jused jin jthe jbrand jname
jdrug. jTherefore, jthe jway jthe jbody jbreaks jdown jand juses jthe jdrug jmay
jdiffer, jwhich jmay jeliminate ja jgeneric jdrug jsubstitution. jCritical
jconcentration jis jthe jamount jof ja jdrug jthat jis jneeded jto jcause ja
jtherapeutic jeffect jand jshould jnot jdiffer jbetween jgeneric jand jbrand jname
jmedications. jDistribution jis jthe jphase jof jpharmacokinetics, jwhich
jinvolves jthe jmovement jof ja jdrug jto jthe jbodys jtissues jand jis jthe jsame jin
jgeneric jand jbrand jname jdrugs. jA jdrugs jhalf-life jis jthe jtime jit jtakes jfor
jthe jamount jof jdrug jto jdecrease jto jhalf jthe jpeak jlevel, jwhich jshould jnot
jchange jwhen jsubstituting ja jgeneric j medication.
5. A jnurse jis jassessing jthe jpatients jhome jmedication juse. jAfter jlistening jto
jthe jpatient jlist jcurrent jmedications, jthe jnurse jasks jwhat jpriority
jquestion?
A) Do jyou jtake jany jgeneric j medications?
B) Are jany jof jthese jmedications jorphan j drugs?
C) Are jthese jmedications jsafe jto jtake jduring j pregnancy?
D) Do jyou jtake jany jover-the-counter j medications?
Ans: D
Feedback:
It jis jimportant jfor jthe jnurse jto jspecifically jquestion juse jof jover-the-
counter jmedications jbecause jpatients jmay jnot jconsider jthem jimportant.
jThe jpatient jis junlikely jto jknow jthe jmeaning jof jorphan jdrugs junless jthey
jtoo jare jhealth jcare jproviders. jSafety jduring jpregnancy, juse jof ja jgeneric
jmedication, jor jclassification jof jorphan jdrugs jare jthings jthe jpatient jwould
jbe junable jto janswer jbut jcould jbe jfound jin jreference jbooks jif jthe jnurse
jwishes jto jresearch jthem.
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,Chapter j1. jIntroduction: jThe jNature jof jDrugs j& jDrug jDevelopment j& jRegulation
1. A jnurse jworking jin jradiology jadministers jiodine jto ja jpatient jwho jis
jhaving ja jcomputed jtomography j(CT) jscan. jThe jnurse jworking jon jthe
joncology junit jadministers jchemotherapy jto jpatients jwho jhave jcancer. jAt
jthe jPublic jHealth jDepartment, ja jnurse jadministers ja jmeasles-mumps-
rubella j(MMR) jvaccine jto ja j14-month-old jchild jas ja jroutine jimmunization.
jWhich jbranch jof jpharmacology jbest jdescribes jthe jactions jof jall jthree
j nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology jis jthe jstudy jof jthe jbiologic jeffects jof jchemicals. jNurses jare
jinvolved jwith jclinical jpharmacology jor jpharmacotherapeutics, jwhich jis ja
jbranch jof jpharmacology jthat jdeals jwith jthe juses jof jdrugs jto jtreat,
jprevent, jand jdiagnose jdisease. jThe jradiology jnurse jis jadministering ja
jdrug jto jhelp jdiagnose ja jdisease. jThe joncology jnurse jis jadministering ja
jdrug jto jhelp jtreat ja jdisease. jPharmacoeconomics jincludes jany jcosts
jinvolved jin jdrug jtherapy.
Pharmacodynamics jinvolves jhow ja jdrug jaffects jthe jbody jand
jpharmacokinetics jis jhow jthe jbody jacts jon jthe jbody.
2. A jphysician jhas jordered jintramuscular j(IM) jinjections jof jmorphine, ja
jnarcotic, jevery j4 jhours jas jneeded jfor jpain jin ja jmotor jvehicle jaccident
jvictim. jThe jnurse jis jaware jthis jdrug jhas ja jhigh jabuse jpotential. jUnder
jwhat jcategory jwould jmorphine jbe jclassified?
A) Schedule jI
B) Schedule jII
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,C) Schedule jIII
D) Schedule jIV
Ans: B
Feedback:
Narcotics jwith ja jhigh jabuse jpotential jare jclassified jas jSchedule jII jdrugs
jbecause jof jsevere jdependence jliability. jSchedule jI jdrugs jhave jhigh
jabuse jpotential jand jno jaccepted jmedical juse. jSchedule jIII jdrugs jhave ja
jlesser jabuse jpotential jthan jII jand jan jaccepted jmedical juse. jSchedule jIV
jdrugs jhave jlow jabuse jpotential jand jlimited jdependence jliability.
3. When jinvolved jin jphase jIII jdrug jevaluation jstudies, jwhat
jresponsibilities jwould jthe jnurse jhave?
A) Working jwith janimals jwho jare jgiven jexperimental j drugs
B) Choosing jappropriate jpatients jto jbe jinvolved jin jthe jdrug j study
C) Monitoring jand jobserving jpatients jclosely jfor jadverse j effects
D) Conducting jresearch jto jdetermine jeffectiveness jof jthe j drug
Ans: C
Feedback:
Phase jIII jstudies jinvolve juse jof ja jdrug jin ja jvast jclinical jpopulation jin
jwhich jpatients jare jasked jto jrecord jany jsymptoms jthey jexperience jwhile
jtaking jthe jdrugs. jNurses jmay jbe jresponsible jfor jhelping jcollect jand
janalyze jthe jinformation jto jbe jshared jwith jthe jFood jand jDrug
jAdministration j(FDA) jbut jwould jnot jconduct jresearch jindependently
jbecause jnurses jdo jnot jprescribe jmedications. jUse jof janimals jin jdrug
jtesting jis jdone jin jthe jpreclinical jtrials. jSelect jpatients jwho jare jinvolved
jin jphase jII jstudies jto jparticipate jin jstudies jwhere jthe jparticipants jhave
jthe jdisease jthe jdrug jis jintended jto jtreat. jThese jpatients jare jmonitored
jclosely jfor jdrug jaction jand jadverse jeffects. jPhase jI jstudies jinvolve
jhealthy jhuman jvolunteers jwho jare jusually jpaid jfor jtheir jparticipation.
jNurses jmay jobserve jfor jadverse jeffects jand jtoxicity.
4. What jconcept jis jconsidered jwhen jgeneric jdrugs jare jsubstituted jfor
jbrand jname jdrugs?
A) Bioavailability
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, B) Critical jconcentration
C) Distribution
D) Half-life
Ans: A
Feedback:
Bioavailability jis jthe jportion jof ja jdose jof ja jdrug jthat jreaches jthe
jsystemic jcirculation jand jis javailable jto jact jon jbody jcells. jBinders jused
jin ja jgeneric jdrug jmay jnot jbe jthe jsame jas jthose jused jin jthe jbrand jname
jdrug. jTherefore, jthe jway jthe jbody jbreaks jdown jand juses jthe jdrug jmay
jdiffer, jwhich jmay jeliminate ja jgeneric jdrug jsubstitution. jCritical
jconcentration jis jthe jamount jof ja jdrug jthat jis jneeded jto jcause ja
jtherapeutic jeffect jand jshould jnot jdiffer jbetween jgeneric jand jbrand jname
jmedications. jDistribution jis jthe jphase jof jpharmacokinetics, jwhich
jinvolves jthe jmovement jof ja jdrug jto jthe jbodys jtissues jand jis jthe jsame jin
jgeneric jand jbrand jname jdrugs. jA jdrugs jhalf-life jis jthe jtime jit jtakes jfor
jthe jamount jof jdrug jto jdecrease jto jhalf jthe jpeak jlevel, jwhich jshould jnot
jchange jwhen jsubstituting ja jgeneric j medication.
5. A jnurse jis jassessing jthe jpatients jhome jmedication juse. jAfter jlistening jto
jthe jpatient jlist jcurrent jmedications, jthe jnurse jasks jwhat jpriority
jquestion?
A) Do jyou jtake jany jgeneric j medications?
B) Are jany jof jthese jmedications jorphan j drugs?
C) Are jthese jmedications jsafe jto jtake jduring j pregnancy?
D) Do jyou jtake jany jover-the-counter j medications?
Ans: D
Feedback:
It jis jimportant jfor jthe jnurse jto jspecifically jquestion juse jof jover-the-
counter jmedications jbecause jpatients jmay jnot jconsider jthem jimportant.
jThe jpatient jis junlikely jto jknow jthe jmeaning jof jorphan jdrugs junless jthey
jtoo jare jhealth jcare jproviders. jSafety jduring jpregnancy, juse jof ja jgeneric
jmedication, jor jclassification jof jorphan jdrugs jare jthings jthe jpatient jwould
jbe junable jto janswer jbut jcould jbe jfound jin jreference jbooks jif jthe jnurse
jwishes jto jresearch jthem.
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