,Contents
Chapter lk1 Introduction lkto lkBiochemistry 1
Chapter lk2 Water 10
Chapter lk3 Amino lkAcids lkand lkthe lkPrimary lkStructures lkof lkProteins 27
Chapter lk4 Proteins: lkThree-Dimensional lkStructure lkand lkFunction 46
Chapter lk5 Properties lkof lkEnzymes 65
Chapter lk6 Mechanisms lkof lkEnzymes 85
Chapter lk7 Coenzymes lkand lkVitamins 104
Chapter lk8 Carbohydrates 119
Chapter lk9 Lipids lkand lkMembranes 137
Chapter lk10 Introduction lkto lkMetabolism 153
Chapter lk11 Glycolysis 169
Chapter lk12 Gluconeogenesis, lkThe lkPentose lkPhosphate lkPathway,
and lkGlycogen lkMetabolism 185
Chapter lk13 The lkCitric lkAcid lkCycle 199
Chapter lk14 Electron lkTransport lkand lkOxidative lkPhosphorylation 213
Chapter lk15 Photosynthesis 227
Chapter lk16 Lipid lkMetabolism 241
Chapter lk17 Amino lkAcid lkMetabolism 256
Chapter lk18 Nucleotide lkMetabolism 269
Chapter lk19 Nucleic lkAcids 284
Chapter lk20 DNA lkReplication, lkRepair, lkand lkRecombination 300
Chapter lk21 Transcription lkand lkRNA lkProcessing 315
Chapter lk22 Protein lkSynthesis 330
Chapter lk23 Recombinant lkDNA lkTechnology 348
,Chapter 1 Introduction to Biochemistry
lk lk lk
1) Which lk elements lkaccount lk for l k more lk than lk97% lk of lkthe lkweight lk of lkmost lkorganisms?
A) C, lk H, lkN, lkMg, lkO, l k S
B) C, lk H, lkN, lkO, lk P, lkS
C) C, lk H, lkN
D) Fe, lkC, lk H, lkO, lk P
E) Ca2+, lkK+, lkNa+, lkMg2+, lkCl-
Answer: l k B
Page lk Ref: lk Section lk 2
2) Proteins lkin lkbiological lk membranes l k may lkbe
A) porous.
B) attached lk to lkthe lk membrane l k surface.
C) span l k the lkmembrane.
D) All lk of lkthe lkabove
E) B lkand lkC lkonly
Answer: l k D
Page lk Ref: lk Section lk 3
3) Which lk statement lkabout lk cellulose lkis lkfalse?
A) It l k is lkthe lkmost lkabundant l k polysaccharide l k in lknature.
B) Its lkmonomers l k are lk joined l k by lkglycosidic lk bonds.
C) It lk is lkpresent lk in lkthe lkstems lkof lkflowering lkplants.
D) The lkhydroxyl lkgroups lkof lkneighboring lkcellulose lkmolecules lkinteract lkto lkform lkstrong,
lkinsoluble lkfibers.
E) It lk is lka l k branched lkpolymer lk of lkglucose.
Answer: l k E
Page lk Ref: lk Section lk 3
1
, 4) When lkKeq lkof lka lk reaction lk= lk1, lkthen
A) the lkforward lk reaction lkis lkfaster lk than lk the lkreverse lk reaction.
B) the lkreverse l k reaction lkis lkfaster lk than lk the lkforward lk reaction.
C) the lkforward lk and lk reverse lk reaction lkrate lkconstants lk are lk equal.
D) more lk products lkare l k formed lkthan lk reactants.
E) fewer l k products lkare lk formed lkthan lk reactants.
Answer: l k C
Page lk Ref: lk Section lk 4
5) Which lk statement lkis lktrue lkabout lk a l k reaction lkwith lkan lkequilibrium lkconstant, lk Keq, lkequal l k to
1000?
lk
A) The lk forward lk rate lkconstant l k is lk1000 lktimes lkgreater l k than lk the lkreverse lk rate lkconstant.
B) The lk forward lkrate lkconstant l k is lk3 l k times lkgreater lk than lkreverse lk rate lkconstant.
C) The lk forward lk rate lkconstant l k is lk1000 lktimes lksmaller lkthan lk the lkreverse lk rate lkconstant.
D) The lk forward lkrate lkconstant l k is lk3 l k times lksmaller lkthan lk the lkreverse lk rate lkconstant.
E) There lkis lknot lk enough l k information l k given lkto lkcompare lkthe lk forward lk and lkreverse lk rate
lk constants.
Answer: l k A
Page lk Ref: lk Section lk 4
6) The lk study lk of lkthe lkenergy lk changes l k during l k metabolic lkreactions lk is lkcalled lk .
A) bioinformatics
B) metabodynamics
C) thermometrics
D) bioenergetics
E) biological lkheat l k dynamics
Answer: l k D
Page lk Ref: lk Section lk 4
7) A lkspontaneous lk chemical lk reaction lkalways l k has l k a l k change.
lk
A) positive lk Gibbʹs lkfree lk energy
B) negative lkGibbʹs lkfree lk energy
C) positive l k enthalpy
D) negative lk enthalpy
E) positive l k entropy
Answer: l k B
Page lk Ref: lk Section lk 4
2
Chapter lk1 Introduction lkto lkBiochemistry 1
Chapter lk2 Water 10
Chapter lk3 Amino lkAcids lkand lkthe lkPrimary lkStructures lkof lkProteins 27
Chapter lk4 Proteins: lkThree-Dimensional lkStructure lkand lkFunction 46
Chapter lk5 Properties lkof lkEnzymes 65
Chapter lk6 Mechanisms lkof lkEnzymes 85
Chapter lk7 Coenzymes lkand lkVitamins 104
Chapter lk8 Carbohydrates 119
Chapter lk9 Lipids lkand lkMembranes 137
Chapter lk10 Introduction lkto lkMetabolism 153
Chapter lk11 Glycolysis 169
Chapter lk12 Gluconeogenesis, lkThe lkPentose lkPhosphate lkPathway,
and lkGlycogen lkMetabolism 185
Chapter lk13 The lkCitric lkAcid lkCycle 199
Chapter lk14 Electron lkTransport lkand lkOxidative lkPhosphorylation 213
Chapter lk15 Photosynthesis 227
Chapter lk16 Lipid lkMetabolism 241
Chapter lk17 Amino lkAcid lkMetabolism 256
Chapter lk18 Nucleotide lkMetabolism 269
Chapter lk19 Nucleic lkAcids 284
Chapter lk20 DNA lkReplication, lkRepair, lkand lkRecombination 300
Chapter lk21 Transcription lkand lkRNA lkProcessing 315
Chapter lk22 Protein lkSynthesis 330
Chapter lk23 Recombinant lkDNA lkTechnology 348
,Chapter 1 Introduction to Biochemistry
lk lk lk
1) Which lk elements lkaccount lk for l k more lk than lk97% lk of lkthe lkweight lk of lkmost lkorganisms?
A) C, lk H, lkN, lkMg, lkO, l k S
B) C, lk H, lkN, lkO, lk P, lkS
C) C, lk H, lkN
D) Fe, lkC, lk H, lkO, lk P
E) Ca2+, lkK+, lkNa+, lkMg2+, lkCl-
Answer: l k B
Page lk Ref: lk Section lk 2
2) Proteins lkin lkbiological lk membranes l k may lkbe
A) porous.
B) attached lk to lkthe lk membrane l k surface.
C) span l k the lkmembrane.
D) All lk of lkthe lkabove
E) B lkand lkC lkonly
Answer: l k D
Page lk Ref: lk Section lk 3
3) Which lk statement lkabout lk cellulose lkis lkfalse?
A) It l k is lkthe lkmost lkabundant l k polysaccharide l k in lknature.
B) Its lkmonomers l k are lk joined l k by lkglycosidic lk bonds.
C) It lk is lkpresent lk in lkthe lkstems lkof lkflowering lkplants.
D) The lkhydroxyl lkgroups lkof lkneighboring lkcellulose lkmolecules lkinteract lkto lkform lkstrong,
lkinsoluble lkfibers.
E) It lk is lka l k branched lkpolymer lk of lkglucose.
Answer: l k E
Page lk Ref: lk Section lk 3
1
, 4) When lkKeq lkof lka lk reaction lk= lk1, lkthen
A) the lkforward lk reaction lkis lkfaster lk than lk the lkreverse lk reaction.
B) the lkreverse l k reaction lkis lkfaster lk than lk the lkforward lk reaction.
C) the lkforward lk and lk reverse lk reaction lkrate lkconstants lk are lk equal.
D) more lk products lkare l k formed lkthan lk reactants.
E) fewer l k products lkare lk formed lkthan lk reactants.
Answer: l k C
Page lk Ref: lk Section lk 4
5) Which lk statement lkis lktrue lkabout lk a l k reaction lkwith lkan lkequilibrium lkconstant, lk Keq, lkequal l k to
1000?
lk
A) The lk forward lk rate lkconstant l k is lk1000 lktimes lkgreater l k than lk the lkreverse lk rate lkconstant.
B) The lk forward lkrate lkconstant l k is lk3 l k times lkgreater lk than lkreverse lk rate lkconstant.
C) The lk forward lk rate lkconstant l k is lk1000 lktimes lksmaller lkthan lk the lkreverse lk rate lkconstant.
D) The lk forward lkrate lkconstant l k is lk3 l k times lksmaller lkthan lk the lkreverse lk rate lkconstant.
E) There lkis lknot lk enough l k information l k given lkto lkcompare lkthe lk forward lk and lkreverse lk rate
lk constants.
Answer: l k A
Page lk Ref: lk Section lk 4
6) The lk study lk of lkthe lkenergy lk changes l k during l k metabolic lkreactions lk is lkcalled lk .
A) bioinformatics
B) metabodynamics
C) thermometrics
D) bioenergetics
E) biological lkheat l k dynamics
Answer: l k D
Page lk Ref: lk Section lk 4
7) A lkspontaneous lk chemical lk reaction lkalways l k has l k a l k change.
lk
A) positive lk Gibbʹs lkfree lk energy
B) negative lkGibbʹs lkfree lk energy
C) positive l k enthalpy
D) negative lk enthalpy
E) positive l k entropy
Answer: l k B
Page lk Ref: lk Section lk 4
2
