20
,
, Chapter1:DNAStructureandFunction d d
Multiple Choice
b
Identify thechoice thatbest completes the statement oranswers thequestion.
b b b d d b b
A. 1. In whichbodyor cellarea are most genes inhumans located?
b b b b b b b b b
A. Nucleus
B. Mitochondrion
C. Cytoplasm
D. Plasma membrane b
A. 2. Whichconditionor statement exemplifies the concept ofgenomics rather thangenetics?
b b b b b b d b b b
A. Thegene for insulin is located onchromosome 11 in allpeople. b b b b b b b b
B. Expressionofanysingle gene is dependent oninheriting two alleles. b b b b b b
C. Sex-linked recessivedisordersaffect malesmoreoftenthan females. b b b
D. Oneallele for each gene is inherited fromthe mother, and one is inherited from b b b b b b b b b b b b
the father.
b b
A. 3. What is the purposeofphosphorous ina DNAstrand?
b b b b b b b b b
A. Linking the nucleotides into a strand b b b b b
B. Holding complementarystrands together b b
C. Ensuring that apurine isalways paired with a pyrimidine d b b b b b b b
D. Preventing the separation ofdouble-stranded DNAinto single-stranded DNA b b b b b b
A. 4. What isthe termused to define alternative formsofa gene that mayresult indifferent
b b b b b b b b b b b b b
expression ofthe trait coded forbythat gene?
b b b b b b
A. Alleles
B. Bases
C. Centromeres
D. Diploids
D. 5. What percentageofbases ina stretchofdouble-stranded DNAthat contains 30% guanine
b b b b b b b b b b
(G) baseswould be adenine (A)?
b b b b
A. 70% b
B. 60% b b
C. 30% b
D. 20% b
C. b 6. What is the termused to describe the organized pictureofthe paired chromosomes within a
b b b b b b b b b b b b b
cell used to determinewhether chromosome numbers, structures, and banding patterns
b b b b b b b b b b
are normal?
b b
A. Pedigree
B. Phenotype
C. Karyotype
D. Autotype
D. 7. What would be the sequence ofDNAthat iscomplementaryto a DNAsectionwiththe base
b b b b b b b b b b b b b b
b sequence of GGTCAATCCTTAG? b b
A. GATTCCTAACTGG
B. TTGACCGAAGGCT
C. AACTGGCTTCCGA
D. CCAGTTAGGAATC
, B. 8. Whichofthese complementarybase pairs formthestrongest or “tightest” association?
b b b b b b b
A. Adenineand thymine b b
B. Cytosineand guanine b b
C. Guanineand thymine b b
D. Cytosine and adenine b b
A 9. What activityoccurs during M phase ofthe cellcycle?
b b b b b b b b b
A. Thecellundergoes cytokinesis. b b
B. Activitystops, and the cell “sleeps.” b b b b
C. AllDNA is completelyreplicated. b d b b
D. The cellgreatly increases protein synthesis. b b b b
B. 10. Whichchromosome number represents the euploid statefor normalhuman somatic cells?
b b b b b b b b b b b
A. 44
B. 46
C. 47
D. 48
A. 11. How doestheproteome differ fromthe genome?
b b b b b b
A. Theproteome changes in responseto intracellular and extracellular signals. b b b b b b b
B. Thegenome changes in responseto intracellular and extracellular signals. b b b b b b b
C. Theproteome is stable in somatic cells and unstable ingermcells, whereas b b b b b b b b b b
the genome is stable in both somatic cellsand germcells.
b b b b b b b b b
D. Thegenome is stable insomatic cells and unstable in germcells, whereas b b b b b b b b b b
the proteome is stable in both somatic cells and germcells.
b b b b b b b b b b
C. 12. What isthe mostoutstanding feature ofa mature haploid cell?
b b b b b b b b b b b
A. It is usually homozygous. d b b
B. The sexchromosomes are missing b b b b
C. Onlyone chromosome ofeach pair is present. b b b b b
D. DNAsynthesis occurs after mitosis instead of before. d b b b b b b
D. 13. At what phaseofthe cellcycle are chromosomes visible as separate structures?
b b b b b b b b b b b
A. G1
B. G2
C. S
D. M
B. 14. b Whichstatement about the cellcycle phase ofG0 istrue?
b b d b b b b b
A. Hyperplastic growth inplaceofhypertrophic growth b b b b
B. Performance ofspecific differentiated functions b b b
C. Initiation and completion ofnucleokinesis b b b
D. Replication ofDNA b
B. 15. b b What isthe result ofnormalDNAreplication?
b b b db
A. Formationoftwo new daughter cells b b b
B. Formationoftwo identicalsets ofDNA b b
C. Disappearance oftheoriginalparent cell b b
D. Activationand attachment of spindlefibers b d b