N5315 - Advanced
Pathophysiology -
Cardiomyopathies and Heart
Failure (Lecture) Questions and
Answers (100% Pass)
Cardiomyopathies tend to result from what?
✓ Tend to result from the neurohormonal responses to ischemic heart
disease or hypertension
What are other causes of cardiomyopathies?
✓ Infectious disease, toxins, systemic connective tissue disorders,
nutritional deficiencies, and infiltrative disorders
What do the pathological consequences of cardiomyopathies affect?
✓ Affect the myocardium layer of the heart impairing contractility or
restricting blood flow through the heart
How many types of cardiomyopathies are there?
✓ 3
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What are the 3 types of cardiomyopathies?
✓ Dilated (DCM); Hypertrophic (HCM); Restrictive
Which cardiomyopathy is characterized by a dilated left ventricle?
✓ Dilated (DCM)
What can you compare Dilated (DCM) cardiomyopathy to?
✓ A worn out ballon; a balloon which has become over stretched and
can no longer hold its normal shape
What is a dilated ventricle unable to do?
✓ Unable to contract sufficiently
What do people with DCM have difficulty with?
✓ Volume overload and pulmonary edema
What are the clinical manifestations of DCM?
✓ Fatigue, dyspnea, S3 heart sound
DCM is most often caused by what?
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✓ Ischemia secondary to MI
What are some other causes of DCM?
✓ Valvular heart disease, diabetes, renal failure, hyperthyroidism, alcohol
use (thiamine deficiency which decreases ATP production), cocaine
use, peripartum complications, genetic disorders, infection such as
Coxsackle B virus, hemochromatosis, and doxorubicin toxicity
What is the most common cause of sudden death in young adults?
✓ Hypertrophic (HCM) cardiomyopathy
What is the most common HCM?
✓ A familial, autosomal dominant disorder; most commonly associated
with gene defects on chromosome 11
What are the pathologic characteristics of HCM?
✓ Hypertrophy of the interventricular septum and to a lesser extent the
left ventricular wall
Hypertrophy of the interventricular septum in HCM may result in what?
Master01 | October, 2024/2025 | Latest update