Pharmacology for Health Professions test
bank exam 2024-2025 9th Edition by
Bruce Colbert, Adam
A 10-year old boy is sent to a pediatric neurologist for an evaluation due to poor
performance and inability to pay attention in school. He has also been fighting with other
children. He is given a diagnosis of ADHD with impulsivity and irratibility. Which is the
most appropriate for management of the ADHD? - CORRECT ANSWER
dextroamphetamine
A 10-year-old boy with ADHD has symptoms that are controlled with an oral
psychostimulant. However, he and his family wish to avoid having to give a second
dose of medication at school. They prefer an alternative treatment that can be
administered in the morning and last the entire day. Which treatment option is best? -
CORRECT ANSWER methylphenidate in a transdermal delivery system
A 12-year old girl has tonic-clonic seizures and is taking phenytoin. What is the
mechanism of action of this drug? - CORRECT ANSWER inactivation of voltage-gated
sodium channels
A 20-year old man is admitted to the emergency room after an accidental overdose of
alprazolam, a benzodiazepine. Which of the following treatment could reverse the effect
of the alprazolam overdose? - CORRECT ANSWER flumazenil
A 23-year old male college student is taking amphetamine on a regular basis to stay
alert while studying. The mechanism of action of amphetamine that causes this effect is:
- CORRECT ANSWER due to the release of norepinephrine from central adrenergic
neurons
A 23-year old man has deliberately ingested an organophosphate insecticide. His initial
symptoms of salivation, lacrimation, and diarrhea are a consequence of - CORRECT
ANSWER inhibition of acetylcholinesterase
A 23-year old man is accosted by 3 men late at night. Immediately his heart rate
increases due to an increase in epinephrine in his circulation. The release of
epinephrine from the adrenal medulla is the result of the action of acetylcholine on -
CORRECT ANSWER nicotine receptors
A 28-year-old woman is brought to the emergency department after overdosing on
oxycodone, an opiate analgesic. She is unconscious and barely breathing when she
arrives at the hospital, but revives and is breathing normally within 2 minutes after
receiving an injection of naloxone. After about an hour, she requires another dose of
,naloxone as the symptoms of opiate overdose begin to redevelop. Naloxone is likely
acting as a - CORRECT ANSWER competitive antagonist of opioid receptors
A 32-year old women is treated for schizophrenia with clozapine. Her physician insists
on regular monitoring of - CORRECT ANSWER complete blood count (CBC)
A 32-year old women with the diagnosis of pheochromocytoma is scheduled for
surgery to remove her adrenal tumor. The best drug to control her episodes of high
blood pressure prior to her surgery would be - CORRECT ANSWER a nonselective a
adrenergic antagonist such as phenoxybenzamine
A 33-year old man is taking valproic acid for tonic-clonic seizures. Lamotrigine is added
to improve seizure control. The plasma concentration of lamotrigine may be increased
because valproate inhibits - CORRECT ANSWER glucuronidation
A 35-year old woman is anesthetized with desflurane for outpatient surgery. The
induction with desflurane is rapid because desflurane is not very soluble in fat and
because desflurane - CORRECT ANSWER has a low blood:gas partitiion coefficient
A 35-year old women complains of not being able to sleep for the past week. She is
prescribed zolpidem to be taken at bedtime. What is the mechanism of action of
zolpidem? - CORRECT ANSWER a nonbenzodiazepine, GABA agonist
A 40-year old man presents to his family physician with drooping eyelids, difficulty
chewing and swallowing, and muscle fatigue even on mild exertion. Which agent could
be used to diagnose myasthenia gravis in this patient? - CORRECT ANSWER
edrophonium
A 65-year old men with the diagnosis of Alzheimer's disease is being treated with
donepezil. This drug acts by - CORRECT ANSWER inhibiting acetylcholinesterase
A 72-year old patient is seeking treatment for chronic open-angle glaucoma, what drug
would you recommend? - CORRECT ANSWER timolol
A 75-year old man with OCD is treated with risperidone. After 3 weeks of therapy, he
develops bradykinesia, loss of facial expressions, and reduced arm movements when
walking. These symptoms are due to - CORRECT ANSWER D2 receptor antagonism
A child is experiencing absence seizures that interrupt his ability to pay attention during
school and activities. Which therapy is most appropriate for this patient? - CORRECT
ANSWER ethosuximide
A drug has a pKa of 7.8. Will the drug favor the protonated or deprotonated form in the
stomach? - CORRECT ANSWER protonated
, A drug with a half-life of 2 hours is administered by continuous intravenous infusion.
How long will it take for the drug to reach 50% of its steady state concentration? -
CORRECT ANSWER 2 hours
A drug, given as a 150 mg single dose, results in a peak plasma concentration of 10
ug/mL. The apparent volume of distribution is (rapid distribution and negligible
elimination prior to measuring the peak plasma level): - CORRECT ANSWER 15 L
A majority of treatments for MS target - CORRECT ANSWER the immune system
A patent with mild depression was being treated with an MAOI, but his physician is now
switching the antidepressant therapy to fluoxetine. How should these medications be
switched out? - CORRECT ANSWER The patient should wait 2 weeks after he stops
taking the MAOI before beginning the SSRI
A patient being treated for schizophrenia develops tardive dyskinesia. Which of the
following agents is most likely to improve this adverse effect? - CORRECT ANSWER
valbenzine
A patient enters the emergency room with bradycardia and hypotension. He reports
eating Amanita muscaria mushrooms, a species known to contain muscarine. What is
the best drug to use as an antidote? - CORRECT ANSWER atropine
A patient is experiencing seizures that result in a loss of consciousness followed by
continuous contraction and rapid contraction/relaxation phases - CORRECT ANSWER
tonic-clonic
A patient need short-term relief for acute asthma symptoms, which drug should be
prescribed? - CORRECT ANSWER albuterol
A patient on a diagnostic test for myasthenia gravis would be expected to have
improved neuromuscular function after being treated with with - CORRECT ANSWER
edrophonium
A patient visits her doctor with symptoms typical of a bladder infection. She is
immediately prescribed a 400 mg dose of antibiotic (t1/2 = 12 hrs). The corresponding
plasma concentration of the drug is found to be 96ug/mL. What is the volume of
distribution of this drug? - CORRECT ANSWER 4.2 L
A patient with Alzheimer disease needs treatment for overactive bladder. Which drug is
the best choice for this patient? - CORRECT ANSWER trospium
A patient with an acute attack of glaucoma is treated with pilocarpine. The primary
reason for its effectiveness in this condition is its: - CORRECT ANSWER ability to
lower intraocular pressure
bank exam 2024-2025 9th Edition by
Bruce Colbert, Adam
A 10-year old boy is sent to a pediatric neurologist for an evaluation due to poor
performance and inability to pay attention in school. He has also been fighting with other
children. He is given a diagnosis of ADHD with impulsivity and irratibility. Which is the
most appropriate for management of the ADHD? - CORRECT ANSWER
dextroamphetamine
A 10-year-old boy with ADHD has symptoms that are controlled with an oral
psychostimulant. However, he and his family wish to avoid having to give a second
dose of medication at school. They prefer an alternative treatment that can be
administered in the morning and last the entire day. Which treatment option is best? -
CORRECT ANSWER methylphenidate in a transdermal delivery system
A 12-year old girl has tonic-clonic seizures and is taking phenytoin. What is the
mechanism of action of this drug? - CORRECT ANSWER inactivation of voltage-gated
sodium channels
A 20-year old man is admitted to the emergency room after an accidental overdose of
alprazolam, a benzodiazepine. Which of the following treatment could reverse the effect
of the alprazolam overdose? - CORRECT ANSWER flumazenil
A 23-year old male college student is taking amphetamine on a regular basis to stay
alert while studying. The mechanism of action of amphetamine that causes this effect is:
- CORRECT ANSWER due to the release of norepinephrine from central adrenergic
neurons
A 23-year old man has deliberately ingested an organophosphate insecticide. His initial
symptoms of salivation, lacrimation, and diarrhea are a consequence of - CORRECT
ANSWER inhibition of acetylcholinesterase
A 23-year old man is accosted by 3 men late at night. Immediately his heart rate
increases due to an increase in epinephrine in his circulation. The release of
epinephrine from the adrenal medulla is the result of the action of acetylcholine on -
CORRECT ANSWER nicotine receptors
A 28-year-old woman is brought to the emergency department after overdosing on
oxycodone, an opiate analgesic. She is unconscious and barely breathing when she
arrives at the hospital, but revives and is breathing normally within 2 minutes after
receiving an injection of naloxone. After about an hour, she requires another dose of
,naloxone as the symptoms of opiate overdose begin to redevelop. Naloxone is likely
acting as a - CORRECT ANSWER competitive antagonist of opioid receptors
A 32-year old women is treated for schizophrenia with clozapine. Her physician insists
on regular monitoring of - CORRECT ANSWER complete blood count (CBC)
A 32-year old women with the diagnosis of pheochromocytoma is scheduled for
surgery to remove her adrenal tumor. The best drug to control her episodes of high
blood pressure prior to her surgery would be - CORRECT ANSWER a nonselective a
adrenergic antagonist such as phenoxybenzamine
A 33-year old man is taking valproic acid for tonic-clonic seizures. Lamotrigine is added
to improve seizure control. The plasma concentration of lamotrigine may be increased
because valproate inhibits - CORRECT ANSWER glucuronidation
A 35-year old woman is anesthetized with desflurane for outpatient surgery. The
induction with desflurane is rapid because desflurane is not very soluble in fat and
because desflurane - CORRECT ANSWER has a low blood:gas partitiion coefficient
A 35-year old women complains of not being able to sleep for the past week. She is
prescribed zolpidem to be taken at bedtime. What is the mechanism of action of
zolpidem? - CORRECT ANSWER a nonbenzodiazepine, GABA agonist
A 40-year old man presents to his family physician with drooping eyelids, difficulty
chewing and swallowing, and muscle fatigue even on mild exertion. Which agent could
be used to diagnose myasthenia gravis in this patient? - CORRECT ANSWER
edrophonium
A 65-year old men with the diagnosis of Alzheimer's disease is being treated with
donepezil. This drug acts by - CORRECT ANSWER inhibiting acetylcholinesterase
A 72-year old patient is seeking treatment for chronic open-angle glaucoma, what drug
would you recommend? - CORRECT ANSWER timolol
A 75-year old man with OCD is treated with risperidone. After 3 weeks of therapy, he
develops bradykinesia, loss of facial expressions, and reduced arm movements when
walking. These symptoms are due to - CORRECT ANSWER D2 receptor antagonism
A child is experiencing absence seizures that interrupt his ability to pay attention during
school and activities. Which therapy is most appropriate for this patient? - CORRECT
ANSWER ethosuximide
A drug has a pKa of 7.8. Will the drug favor the protonated or deprotonated form in the
stomach? - CORRECT ANSWER protonated
, A drug with a half-life of 2 hours is administered by continuous intravenous infusion.
How long will it take for the drug to reach 50% of its steady state concentration? -
CORRECT ANSWER 2 hours
A drug, given as a 150 mg single dose, results in a peak plasma concentration of 10
ug/mL. The apparent volume of distribution is (rapid distribution and negligible
elimination prior to measuring the peak plasma level): - CORRECT ANSWER 15 L
A majority of treatments for MS target - CORRECT ANSWER the immune system
A patent with mild depression was being treated with an MAOI, but his physician is now
switching the antidepressant therapy to fluoxetine. How should these medications be
switched out? - CORRECT ANSWER The patient should wait 2 weeks after he stops
taking the MAOI before beginning the SSRI
A patient being treated for schizophrenia develops tardive dyskinesia. Which of the
following agents is most likely to improve this adverse effect? - CORRECT ANSWER
valbenzine
A patient enters the emergency room with bradycardia and hypotension. He reports
eating Amanita muscaria mushrooms, a species known to contain muscarine. What is
the best drug to use as an antidote? - CORRECT ANSWER atropine
A patient is experiencing seizures that result in a loss of consciousness followed by
continuous contraction and rapid contraction/relaxation phases - CORRECT ANSWER
tonic-clonic
A patient need short-term relief for acute asthma symptoms, which drug should be
prescribed? - CORRECT ANSWER albuterol
A patient on a diagnostic test for myasthenia gravis would be expected to have
improved neuromuscular function after being treated with with - CORRECT ANSWER
edrophonium
A patient visits her doctor with symptoms typical of a bladder infection. She is
immediately prescribed a 400 mg dose of antibiotic (t1/2 = 12 hrs). The corresponding
plasma concentration of the drug is found to be 96ug/mL. What is the volume of
distribution of this drug? - CORRECT ANSWER 4.2 L
A patient with Alzheimer disease needs treatment for overactive bladder. Which drug is
the best choice for this patient? - CORRECT ANSWER trospium
A patient with an acute attack of glaucoma is treated with pilocarpine. The primary
reason for its effectiveness in this condition is its: - CORRECT ANSWER ability to
lower intraocular pressure
