Test Bank Ch 7
1. Dental caries is caused by an infection with:
a. Porphyromonas gingivalis
b. Eikenella corrodens
c. Streptococcus mutans
d. Fusobacterium - ✔✔ANSW✔✔..ANS: c
Dental caries is produced by Streptococcus mutans. It is the first important dental
infection of the newly erupting teeth of the young patient.
Incorrect choices: Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis,
Prevotella intermedia, Eikenella corrodens, Fusobacterium spp., and Campylobacter
rectus are all periodontal microbes.
REF: pp. 76-77
2. Which of the following choices is the dental health care team's biggest problem in the
adult patient?
a. Caries
b. Periodontal disease
c. Localized dental infection
d. Systemic dental infection - ✔✔ANSW✔✔..ANS: b
Periodontal disease is the dental health care team's biggest problem in the adult patient.
With an increase in knowledge about antiinfective agents, dental teams will be better
able to understand and administer new treatments properly for this disease, such as
tetracycline fibers.
REF: p. 76
3. If an infection is just beginning, the organisms most likely to be present are:
a. Gram-positive cocci
b. Gram-negative cocci
c. Gram-positive anaerobes
d. Gram-negative anaerobes - ✔✔ANSW✔✔..ANS: a
Gram-positive cocci are most likely to present if the infection is just beginning. After a
short time, the gram-positive infection begins to include a variety of both gram-positive
and gram-negative anaerobic organisms. With additional time and no treatment, the
infection progresses until it consists of predominantly anaerobic flora.
REF: p. 77
,4. Which of the following agents is the drug of choice for an early dental infection unless
the patient is allergic to it?
a. Erythromycin
b. Clindamycin
c. Penicillin
d. Metronidazole - ✔✔ANSW✔✔..ANS: c
Correct: Penicillin is the drug of choice unless the patient is allergic to it. Amoxicillin is
most often used because it is less irritating to the stomach than other drugs and can be
taken with food or milk.
Incorrect choices: In patients allergic to penicillin, alternatives might include
erythromycin or clindamycin. When the infection is at the mixed stage, agents effective
against either gram-positive or anaerobic organisms may be successful. Metronidazole
is effective for anaerobic organisms.
REF: p. 77
5. Which of the following antibiotics is associated with pseudomembranous colitis?
a. Penicillin
b. Erythromycin
c. Clindamycin
d. Metronidazole - ✔✔ANSW✔✔..ANS: c
Clindamycin is associated with pseudomembranous colitis. Historically, oral surgeons
have been comfortable using clindamycin, but other dentists have avoided it.
Clindamycin affects both gram-positive cocci and gram-positive and gram-negative
anaerobes.
REF: p. 77
6. An __________ agent is a chemical substance produced by a microorganism that
has the capacity, in dilute solutions, to destroy or suppress the growth or multiplication
of organisms or to suppress their action.
a. Antiinfective
b. Antibacterial
c. Antibiotic
d. Antimicrobial - ✔✔ANSW✔✔..ANS: c
Correct: An antibiotic is a chemical substance produced by a microorganism.
Incorrect choices: The difference among the terms antibiotic, antiinfective, and
antibacterial is that antibiotics are produced by microorganisms, whereas the other
agents may be developed in a chemistry laboratory and not from a living organism. This
difference is largely ignored in general conversation, and antiinfectives are often called
antibiotics.
REF: p. 78
, 7. Which of the following antiinfective agents is bacteriostatic rather than bactericidal?
a. Cephalosporins
b. Metronidazole
c. Penicillins
d. Tetracyclines
e. Vancomycin - ✔✔ANSW✔✔..ANS: d
Correct: Tetracyclines—chloramphenicol, spectinomycin, sulfonamides, and
trimethoprim—are all bacteriostatic. Clindamycin and macrolides also are bacteriostatic,
but may be bactericidal against some organisms at higher blood levels.
Incorrect choices: Aminoglycosides—bacitracin, cephalosporins, metronidazole,
penicillins, polymyxin, quinolones, rifampin, and vancomycin—are all bactericidal
antiinfective agents.
REF: p. 78
8. The nonhomeostatic multiplication of organisms with the body is called:
a. Resistance
b. Superinfection
c. Infection
d. Virulence - ✔✔ANSW✔✔..ANS: c
Correct: Infection is an unchecked increase in the number of pathogenic bacteria in the
body.
Incorrect choices: Resistance is the ability of an organism to be immune to the effects of
an antiinfective agent. Superinfection is an opportunistic infection that arises as a
consequence of treatment. Virulence is the disease-producing power of the
microorganism.
REF: p. 78
9. Similar to the MAC of general anesthesia, the MIC is a measure of potency. The
lower the MIC is, the higher the potency will be.
a. Both statements are true.
b. Both statements are false.
c. The first statement is true, the second statement is false.
d. The first statement is false, the second statement is true. - ✔✔ANSW✔✔..ANS: a
Correct: MAC and MIC are both measures of pharmacologic potency, and as with the
MAC, the lower the MIC is, the higher the potency will be. MIC is the minimal inhibitory
concentration of an antibacterial; MAC is the maximal alveolar concentration.
REF: p. 78