NSG 6005 Week 2 Pharmacology Quiz The major reason for not crushing a sustained release capsule is that, if crushed, the coated beads of the drugs could possibly result in: o Disintegration o Toxicity o Malabsorption o Deterioration - ANSWER

NSG 6005 Week 2 Pharmacology Quiz The major reason for not crushing a sustained release capsule is that, if crushed, the coated beads of the drugs could possibly result in: o Disintegration o Toxicity o Malabsorption o Deterioration - ANSWER o Toxicity Drugs that have a significant first pass effect: o Must be given by enteral (oral) route only o Bypass the hepatic circulation o Are rapidly metabolized by the liver and may have little if any desired action o Are converted by the liver to more active in fat-soluble forms - ANSWER o Are rapidly metabolized by the liver and may have little if any desired action When obtaining a drug history from Harold, he gives you a complete list of his prescription medications. He denies taking any other drugs, but you find that he occasionally takes aspirin for his arthritis flare-ups. This is an example of: o His appropriately only telling you about his regularly prescribed medications