ONS/ONCC CHEMOTHERAPY/IMMUNOTHERAPY LESSON 6: SYMPTOMS THAT CAN BE DOSE-LIMITING; LESSON 7: CUMULATIVE DOSE Exam | Questions & 100% Correct Answers (Verified) | Latest Update | Grade A

Cumulative dose Correct Answer: total amount of one antineoplastic agent given to the pt, adding up each time that the pt has received it Cumulative lifetime dose Correct Answer: -"cumulative dose should not exceed..."-total amount of specific antineoplastic agents that can be safely given over the course of a pt's lifetime -critical to track lifetime dose Chemotherapy Induced nausea & Vomiting (CINV) Correct Answer: -primary prevention strategy is through consistent use of optimal antiemetic therapy beginning with initial cycle 2 -prevention is pivotal when attempting to maximize pt quality of life and crucial to preventing delays in treatment Two Neural Pathways associated with chemo emetic response Correct Answer: 1.Peripheral pathway al pathway Two neurotransmitters involved in vomiting Correct Answer: 1. serotonin 2. substance P 5-HT3 receptor antagonists Correct Answer: active in peripheral path and counteract acute nausea and vomiting by blocking serotonin activity e.g. Aloxi NK1 dependent mechanism Correct Answer: active in central pathway and is active in the late-acute phase/delayed phase -substance P acts on NK1 receptors -Aprepitant Uncontrolled CINV can cause patient to become