Maryville Pharm 615 Exam 2 Elle's Review Latest 2024/2025 Questions & Answers Verified Answers (100% CORRECT ANSWERS)

1. Henry has recently started on carbamazepine to treat seizures. He comes to see you and you note that while his carbamazepine levels had been in the therapeutic range they are now low. The possible cause for the low carbamazepine levels include: - ANSWER Carbamazepine auto-induces metabolism, leading to lower levels despite good compliance. 2. Carbamazepine has a Black Box Warning due to life-threatening: - ANSWER Dermatologic reaction, including Steven's Johnson and toxic epidermal necrolysis 3. Long-term monitoring of patients who are taking carbamazepine includes: - ANSWER Complete blood count every 3 to 4 months (can be a decrease in WBC & platelets) Six-year-old Felisha has recently been started on ethosuximide (Zarontin) for seizures. She should be monitored for: - ANSWER Blood dyscrasias, which are uncommon but possible What should families be taught regarding seizure activity monitoring? - ANSWER Prevention of seizures, patient safety, quality of life issues, reach acceptable goals for treatment, & do not abruptly stop taking seizure meds What electrolyte imbalance is associated with topiramate? - ANSWER Decreased sodium bicarb leading to hyperchloremic metabolic acidosis Lisa who is overweight recently started taking topiramate for seizures and at her follow-up visit you note she has lost 4 kg. The appropriate action would be: - ANSWER Reassure her that this is a normal side effect of topiramate and continue to monitor her weight. Travis's seizures are well controlled on topiramate and he wants to start playing baseball. Education for Travis regarding his topiramate includes: - ANSWER He should monitor his temperature and ability to sweat in the heat while playing 9. Brandy is taking valproate (Depakote) for seizures and would like to get pregnant. What advice would you give her? - ANSWER Valproate is a known teratogen, but may be taken after the first trimester if necessary. Keppra is a better drug to be on until the second trimester, then she can go back to valproate. 10. What category is valproate? - ANSWER Category X