Test Bank
McCance & Huether’s
Pathophysiology
The Biologic Basis for Disease in Adults and Children
9th Edition
,Pathophysiology The Biologic Basis for Disease in Adults and Children 9th Edition 97803235834
Chapter 1 - Cellular Biology 3
Chapter 2 - Altered Cellular and Tissue Biology Environmental Agents 16
Chapter 3 - The Cellular Environment Fluids and Electrolytes Acids and
Bases 28
Chapter 4 - Genes and Genetic Diseases 41
Chapter 5 - Genes Environment-Lifestyle and Common Diseases 51
Chapter 6 - Epigenetics and Disease 59
Chapter 7 - Innate Immunity Inflammation 64
Chapter 8 - Adaptive Immunity 78
Chapter 9 - Alterations in Immunity and Inflammation 89
Chapter 10 - Infection 102
Chapter 11 - Stress and Disease 110
Chapter 12 - Cancer Biology 117
Chapter 13 - Cancer Epidemiology 129
Chapter 14 - Cancer in Children 135
Chapter 15 - Structure and Function of the Neurologic System 140
Chapter 16 - Pain Temperature Regulation Sleep and Sensory Function 151
Chapter 17 - Alterations in Cognitive Systems Cerebral Hemodynamics and
Motor Function 165
Chapter 18 - Disorders of the Central and Peripheral Nervous Systems and
the Neuromuscular Junction 179
Chapter 19 - Neurobiology of Schizophrenia Mood Disorders and Anxiety
Disorders 189
Chapter 20 - Alterations of Neurologic Function in Children 195
Chapter 21 - Mechanisms of Hormonal Regulation 202
Chapter 22 - Alterations of Hormonal Regulation 211
Chapter 23 - Obesity and Disorders of Nutrition NEW 223
Chapter 24 - Structure and Function of the Reproductive Systems 228
Chapter 25 - Alterations of the Female Reproductive System 237
Chapter 26 - Alterations of the Male Reproductive System 246
,Pathophysiology The Biologic Basis for Disease in Adults and Children 9th Edition 97803235834
Chapter 27 - Sexually Transmitted Infections 252
Chapter 28 - Structure and Function of the Hematologic System 260
Chapter 29 - Alterations of Erythrocyte Platelet and Hemostatic Function 270
Chapter 30 - Alterations of Leukocyte and Lymphoid Function 280
Chapter 31 - Alterations of Hematologic Function in Children 287
Chapter 32 - Structure and Function of the Cardiovascular and Lymphatic
Systems 297
Chapter 33 - Alterations of Cardiovascular Function 309
Chapter 34 - Alterations of Cardiovascular Function in Children 323
Chapter 35 - Structure and Function of the Pulmonary System 331
Chapter 36 - Alterations of Pulmonary Function 341
Chapter 37 - Alterations of Pulmonary Function in Children 357
Chapter 38 - Structure and Function of the Renal and Urologic Systems 365
Chapter 39 - Alterations of Renal and Urinary Function 375
Chapter 40 - Alterations of Renal and Urinary Tract Function in Children 385
Chapter 41 - Structure and Function of the Digestive System 393
Chapter 42 - Alterations of Digestive Function 404
Chapter 43 - Alterations of Digestive Function in Children 415
Chapter 44 - Structure and Function of the Musculoskeletal System 424
Chapter 45 - Alterations of Musculoskeletal Function 436
Chapter 46 - Alterations of Musculoskeletal Function in Children 448
Chapter 47 - Structure Function and Disorders of the Integument 457
Chapter 48 - Alterations of the Integument in Children 468
Chapter 49 - Shock Multiple Organ Dysfunction Syndrome and Burns in
Adults 476
Chapter 50 - Shock Multiple Organ Dysfunction Syndrome and Burns in
Children 483
, Pathophysiology The Biologic Basis for Disease in Adults and Children 9th Edition 97803235834
Chapter 01: Cellular Biology
McCance/Huether: Pathophysiology: The Biologic Basis of Disease in Adults and
Children, 9th Edition
MULTIPLE CHOICE
1. Which statement best describes the cellular function of metabolic absorption?
a. Cells can produce proteins.
b. Cells can secrete digestive enzymes.
c. Cells can take in and use nutrients.
d. Cells can synthesize fats.
ANS: C
In metabolic absorption, all cells take in and use nutrients and other substances from their
surroundings. The remaining options are not inclusive in their descriptions of cellular
metabolic absorption.
PTS: 1 DIF: Cognitive Level: Remembering
2. Where is most of a cell’s genetic information, including RNA and DNA, contained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS: C
The nucleus contains the nucleolus, a small dense structure composed largely of RNA, most
of the cellular DNA, and the DNA-binding proteins, such as the histones, which regulate its
activity. The mitochondria are responsible for cellular respiration and energy production.
Ribosomes’ chief function is to provide sites for cellular protein synthesis. Lysosomes
function as the intracellular digestive system.
PTS: 1 DIF: Cognitive Level: Remembering
3. Which component of the cell produces hydrogen peroxide (H2O2) by using oxygen to remove
hydrogen atoms from specific substrates in an oxidative reaction?
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS: B
Chapter 1 - Cellular Biology 3
McCance & Huether’s
Pathophysiology
The Biologic Basis for Disease in Adults and Children
9th Edition
,Pathophysiology The Biologic Basis for Disease in Adults and Children 9th Edition 97803235834
Chapter 1 - Cellular Biology 3
Chapter 2 - Altered Cellular and Tissue Biology Environmental Agents 16
Chapter 3 - The Cellular Environment Fluids and Electrolytes Acids and
Bases 28
Chapter 4 - Genes and Genetic Diseases 41
Chapter 5 - Genes Environment-Lifestyle and Common Diseases 51
Chapter 6 - Epigenetics and Disease 59
Chapter 7 - Innate Immunity Inflammation 64
Chapter 8 - Adaptive Immunity 78
Chapter 9 - Alterations in Immunity and Inflammation 89
Chapter 10 - Infection 102
Chapter 11 - Stress and Disease 110
Chapter 12 - Cancer Biology 117
Chapter 13 - Cancer Epidemiology 129
Chapter 14 - Cancer in Children 135
Chapter 15 - Structure and Function of the Neurologic System 140
Chapter 16 - Pain Temperature Regulation Sleep and Sensory Function 151
Chapter 17 - Alterations in Cognitive Systems Cerebral Hemodynamics and
Motor Function 165
Chapter 18 - Disorders of the Central and Peripheral Nervous Systems and
the Neuromuscular Junction 179
Chapter 19 - Neurobiology of Schizophrenia Mood Disorders and Anxiety
Disorders 189
Chapter 20 - Alterations of Neurologic Function in Children 195
Chapter 21 - Mechanisms of Hormonal Regulation 202
Chapter 22 - Alterations of Hormonal Regulation 211
Chapter 23 - Obesity and Disorders of Nutrition NEW 223
Chapter 24 - Structure and Function of the Reproductive Systems 228
Chapter 25 - Alterations of the Female Reproductive System 237
Chapter 26 - Alterations of the Male Reproductive System 246
,Pathophysiology The Biologic Basis for Disease in Adults and Children 9th Edition 97803235834
Chapter 27 - Sexually Transmitted Infections 252
Chapter 28 - Structure and Function of the Hematologic System 260
Chapter 29 - Alterations of Erythrocyte Platelet and Hemostatic Function 270
Chapter 30 - Alterations of Leukocyte and Lymphoid Function 280
Chapter 31 - Alterations of Hematologic Function in Children 287
Chapter 32 - Structure and Function of the Cardiovascular and Lymphatic
Systems 297
Chapter 33 - Alterations of Cardiovascular Function 309
Chapter 34 - Alterations of Cardiovascular Function in Children 323
Chapter 35 - Structure and Function of the Pulmonary System 331
Chapter 36 - Alterations of Pulmonary Function 341
Chapter 37 - Alterations of Pulmonary Function in Children 357
Chapter 38 - Structure and Function of the Renal and Urologic Systems 365
Chapter 39 - Alterations of Renal and Urinary Function 375
Chapter 40 - Alterations of Renal and Urinary Tract Function in Children 385
Chapter 41 - Structure and Function of the Digestive System 393
Chapter 42 - Alterations of Digestive Function 404
Chapter 43 - Alterations of Digestive Function in Children 415
Chapter 44 - Structure and Function of the Musculoskeletal System 424
Chapter 45 - Alterations of Musculoskeletal Function 436
Chapter 46 - Alterations of Musculoskeletal Function in Children 448
Chapter 47 - Structure Function and Disorders of the Integument 457
Chapter 48 - Alterations of the Integument in Children 468
Chapter 49 - Shock Multiple Organ Dysfunction Syndrome and Burns in
Adults 476
Chapter 50 - Shock Multiple Organ Dysfunction Syndrome and Burns in
Children 483
, Pathophysiology The Biologic Basis for Disease in Adults and Children 9th Edition 97803235834
Chapter 01: Cellular Biology
McCance/Huether: Pathophysiology: The Biologic Basis of Disease in Adults and
Children, 9th Edition
MULTIPLE CHOICE
1. Which statement best describes the cellular function of metabolic absorption?
a. Cells can produce proteins.
b. Cells can secrete digestive enzymes.
c. Cells can take in and use nutrients.
d. Cells can synthesize fats.
ANS: C
In metabolic absorption, all cells take in and use nutrients and other substances from their
surroundings. The remaining options are not inclusive in their descriptions of cellular
metabolic absorption.
PTS: 1 DIF: Cognitive Level: Remembering
2. Where is most of a cell’s genetic information, including RNA and DNA, contained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS: C
The nucleus contains the nucleolus, a small dense structure composed largely of RNA, most
of the cellular DNA, and the DNA-binding proteins, such as the histones, which regulate its
activity. The mitochondria are responsible for cellular respiration and energy production.
Ribosomes’ chief function is to provide sites for cellular protein synthesis. Lysosomes
function as the intracellular digestive system.
PTS: 1 DIF: Cognitive Level: Remembering
3. Which component of the cell produces hydrogen peroxide (H2O2) by using oxygen to remove
hydrogen atoms from specific substrates in an oxidative reaction?
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS: B
Chapter 1 - Cellular Biology 3
