NR 566 Midterm NR566 MIDTERM
EXAM REVIEW /LATEST ADVANCED
PHARMACOLOGY FOR CARE OF
FAMILY|AGRADE
Which non-amphetamines are FDA approved for weight loss that have lower
abuse risk? - {✔✔ANSWER✔✔}-Phentermine and Diethylpropion
Phentermine adverse effects - {✔✔ANSWER✔✔}--increase HR and BP
-dry mouth and constipation
What is role of topiramate in weight loss? - {✔✔ANSWER✔✔}-Increases
satiety
What are some Phentermine/topiramate contraindications for use? -
{✔✔ANSWER✔✔}-not approved in children and contraindicated with severe
hepatic impairment
,How should we educate patient to take Phentermine/topiramate to avoid
insomnia? - {✔✔ANSWER✔✔}-given before 1600
What are some high-risk patient conditions that we should use
Phentermine/topiramate with caution? - {✔✔ANSWER✔✔}-hx drug abuse,
glaucoma, pregnant, HTN, hyperthyroidism
Phentermine/topiramate adverse effects - {✔✔ANSWER✔✔}-insomnia,
nervousness, anxiety, depression, blurred vision
Which of the following would be a contraindication to prescribing
phentermine/topiramate? Select all that apply. - {✔✔ANSWER✔✔}-A)
Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E
ANSWER: A,C,D
Orlistat is a lipase inhibitor that acts on the _________ and reduces absorption of
fat by 30%. - {✔✔ANSWER✔✔}-GI tract
Take multivitamin ___hours before/after to supplement fat-soluble vitamins that
may not be absorbed well when taking Orlistat. - {✔✔ANSWER✔✔}-2
,Orlistat is OTC as 60 mg TID with meals. Not approved in children <____. -
{✔✔ANSWER✔✔}-12
Orlistat results in the least amount of weight loss of all. How much? -
{✔✔ANSWER✔✔}-2-3% body weight (7 lbs in year)
Orlistat adverse effects - {✔✔ANSWER✔✔}-Fecal incontinence, oily rectal
leakage, flatus, abdominal cramps. liver damage (light-colored stools, dark urine,
fatigue, jaundice, anorexia)
When is Orlistat contraindicated? - {✔✔ANSWER✔✔}-In those with
malabsorption syndrome or cholestasis
What vitamin deficiency are we concerned about when taking Orlistat...especially
if the patient is on coumadin? - {✔✔ANSWER✔✔}-Monitor Coumadin as
Vitamin K deficiency may occur and intensify effect of Coumadin.
A patient with a BMI of 27 would be considered: - {✔✔ANSWER✔✔}-
overweight
Lorcaserin adverse effects - {✔✔ANSWER✔✔}-headache, URI, back pain,
hypoglycemia (in DM), blood dyscrasias, cognitive impairment, psychiatric
disorders, priapism, pulmonary hypertension, and valvular heart disease
Lorcaserin MOA - {✔✔ANSWER✔✔}-Reduces waist circumference, fasting
glucose, insulin, total cholesterol, LDL, triglycerides
, When is Lorcaserin contraindicated? - {✔✔ANSWER✔✔}-CrCl <30
-Not approved in children
Lorcaserin drug interactions - {✔✔ANSWER✔✔}--MAOI inhibitors, SSRIs,
SNRIs, St. Johns wart, and triptans
-Increased risk for serotonin syndrome
Naltrexone and Bupropion black box warning - {✔✔ANSWER✔✔}-increased
risk for suicidal ideation and suicide attempts in children, adolescents, and young
adults
Do not take Naltrexone and Bupropion within ___weeks of taking a _____. -
{✔✔ANSWER✔✔}--two
-MAOI
Due to Naltrexone and Bupropion antagonist effects, it can reduce effects of
what? - {✔✔ANSWER✔✔}-opioids
How does Phentermine and Diethylpropion promote weight loss? -
{✔✔ANSWER✔✔}--Promote weight loss by decreasing appetite
-They are central nervous system (CNS) stimulants that suppress appetite by
increasing the availability of norepinephrine at receptors in the brain
What is the maximum recommended duration of use for non-amphetamines? -
{✔✔ANSWER✔✔}-3 months or less
EXAM REVIEW /LATEST ADVANCED
PHARMACOLOGY FOR CARE OF
FAMILY|AGRADE
Which non-amphetamines are FDA approved for weight loss that have lower
abuse risk? - {✔✔ANSWER✔✔}-Phentermine and Diethylpropion
Phentermine adverse effects - {✔✔ANSWER✔✔}--increase HR and BP
-dry mouth and constipation
What is role of topiramate in weight loss? - {✔✔ANSWER✔✔}-Increases
satiety
What are some Phentermine/topiramate contraindications for use? -
{✔✔ANSWER✔✔}-not approved in children and contraindicated with severe
hepatic impairment
,How should we educate patient to take Phentermine/topiramate to avoid
insomnia? - {✔✔ANSWER✔✔}-given before 1600
What are some high-risk patient conditions that we should use
Phentermine/topiramate with caution? - {✔✔ANSWER✔✔}-hx drug abuse,
glaucoma, pregnant, HTN, hyperthyroidism
Phentermine/topiramate adverse effects - {✔✔ANSWER✔✔}-insomnia,
nervousness, anxiety, depression, blurred vision
Which of the following would be a contraindication to prescribing
phentermine/topiramate? Select all that apply. - {✔✔ANSWER✔✔}-A)
Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E
ANSWER: A,C,D
Orlistat is a lipase inhibitor that acts on the _________ and reduces absorption of
fat by 30%. - {✔✔ANSWER✔✔}-GI tract
Take multivitamin ___hours before/after to supplement fat-soluble vitamins that
may not be absorbed well when taking Orlistat. - {✔✔ANSWER✔✔}-2
,Orlistat is OTC as 60 mg TID with meals. Not approved in children <____. -
{✔✔ANSWER✔✔}-12
Orlistat results in the least amount of weight loss of all. How much? -
{✔✔ANSWER✔✔}-2-3% body weight (7 lbs in year)
Orlistat adverse effects - {✔✔ANSWER✔✔}-Fecal incontinence, oily rectal
leakage, flatus, abdominal cramps. liver damage (light-colored stools, dark urine,
fatigue, jaundice, anorexia)
When is Orlistat contraindicated? - {✔✔ANSWER✔✔}-In those with
malabsorption syndrome or cholestasis
What vitamin deficiency are we concerned about when taking Orlistat...especially
if the patient is on coumadin? - {✔✔ANSWER✔✔}-Monitor Coumadin as
Vitamin K deficiency may occur and intensify effect of Coumadin.
A patient with a BMI of 27 would be considered: - {✔✔ANSWER✔✔}-
overweight
Lorcaserin adverse effects - {✔✔ANSWER✔✔}-headache, URI, back pain,
hypoglycemia (in DM), blood dyscrasias, cognitive impairment, psychiatric
disorders, priapism, pulmonary hypertension, and valvular heart disease
Lorcaserin MOA - {✔✔ANSWER✔✔}-Reduces waist circumference, fasting
glucose, insulin, total cholesterol, LDL, triglycerides
, When is Lorcaserin contraindicated? - {✔✔ANSWER✔✔}-CrCl <30
-Not approved in children
Lorcaserin drug interactions - {✔✔ANSWER✔✔}--MAOI inhibitors, SSRIs,
SNRIs, St. Johns wart, and triptans
-Increased risk for serotonin syndrome
Naltrexone and Bupropion black box warning - {✔✔ANSWER✔✔}-increased
risk for suicidal ideation and suicide attempts in children, adolescents, and young
adults
Do not take Naltrexone and Bupropion within ___weeks of taking a _____. -
{✔✔ANSWER✔✔}--two
-MAOI
Due to Naltrexone and Bupropion antagonist effects, it can reduce effects of
what? - {✔✔ANSWER✔✔}-opioids
How does Phentermine and Diethylpropion promote weight loss? -
{✔✔ANSWER✔✔}--Promote weight loss by decreasing appetite
-They are central nervous system (CNS) stimulants that suppress appetite by
increasing the availability of norepinephrine at receptors in the brain
What is the maximum recommended duration of use for non-amphetamines? -
{✔✔ANSWER✔✔}-3 months or less
