TEST BANK FOR RUBIN’S PATHOLOGY:
CLINICOPATHOLOGIC FOUNDATIONS OF
MEDICINE 7TH EDITION ( WITH ANSWER
KEY)
LATEST UPDATED EXAMINATION STUDY
GUIDE 2023
GUARANTEED GRADE A+
Chapter 1: Cell Adaptation, Injury and Death
Ischemia and other toxic injuries increase the accumulation of intracellular calcium as a result
1. of:
A) release of stored calcium from the mitochondria.
B) improved intracellular volume regulation.
C) decreased influx across the cell membrane.
D) attraction of calcium to fatty infiltrates.
The patient is found to have liver disease, resulting in the removal of a lobe of his liver.
2. Adaptation to the reduced size of the liver leads to _ of the remaining liver cells.
A) metaplasia
B) organ atrophy
C) compensatory hyperplasia
D) physiologic hypertrophy
A person eating peanuts starts choking and collapses. His airway obstruction is partially
cleared, but he remains hypoxic until he reaches the hospital. The prolonged cell hypoxia
3. caused a cerebral infarction and resulting _ in the brain.
A) caspase activation
B) coagulation necrosis
C) rapid phagocytosis
D) protein p53 deficiency
Bacteria and viruses cause cell damage by , which is unique from the intracellular
4. damage caused by other injurious agents.
A) disrupting the sodium/potassium ATPase pump
B) interrupting oxidative metabolism processes
C) replicating and producing continued injury
,TEST BANK FOR RUBIN’S PATHOLOGY:
CLINICOPATHOLOGIC FOUNDATIONS OF
MEDICINE 7TH EDITION ( WITH ANSWER
KEY)
LATEST UPDATED EXAMINATION STUDY
GUIDE 2023
GUARANTEED GRADE A+
D) decreasing protein synthesis and function
The patient has a prolonged interruption in arterial blood flow to his left kidney, causing
5. hypoxic cell injury and the release of free radicals. Free radicals damage cells by:
A) destroying phospholipids in the cell membrane.
B) altering the immune response of the cell.
C) disrupting calcium storage in the cell.
D) inactivation of enzymes and mitochondria.
,TEST BANK FOR RUBIN’S PATHOLOGY: CLI
/ / / / //
NICOPATHOLOGICFOUNDATIONS OF ME / / //
DICINE 7TH EDITION ( WITH ANSWER KEY)
/ / / / / //
LATEST UPDATED EXAMINATION STUDY G
/ / / //
UIDE 2023
/
GUARANTEED GRADE A+ / /
6. Injured/cells/have/impaired/flow/of/substances/through/the/cell/membrane/as/a/result/of:
A) increased/fat/load.
B) altered/permeability.
C) altered/glucose/utilization.
D) increased/surface/receptors.
7. Reversible/adaptive/intracellular/responses/are/initiated/by:
A) stimulus/overload.
B) genetic/mutations.
C) chemical/messengers.
D) mitochondrial/DNA.
8. Injured/cells/become/very/swollen/as/a/result/of:
A) increased/cell/protein/synthesis.
B) altered/cell/volume/regulation.
C) passive/entry/of/potassium/into/the/cell.
D) bleb/formation/in/the/plasma/membrane.
A/diabetic/patient/has/impaired/sensation,/circulation,/and/oxygenation/of/his/feet./He/steps/on/a/
piece/of/glass,/the/wound/does/not/heal,/and/the/area/tissue/becomes/necrotic./The/necrotic
9. cell/death/is/ characterized/by:
A) rapid/apoptosis.
B) cellular/rupture.
C) shrinkage/and/collapse.
D) chronic/inflammation.
A/99-year-old/woman/has/experienced/the/decline/of/cell/function/associated/with/age./A
10. group/of/theories/ of/cellular/aging/focus/on/programmed:
A) changes/with/genetic/influences.
B) elimination/of/cell/receptor/sites.
C) insufficient/telomerase/enzyme.
, TEST BANK FOR RUBIN’S PATHOLOGY: CLI
/ / / / //
NICOPATHOLOGICFOUNDATIONS OF ME / / //
DICINE 7TH EDITION ( WITH ANSWER KEY)
/ / / / / //
LATEST UPDATED EXAMINATION STUDY G
/ / / //
UIDE 2023
/
GUARANTEED GRADE A+ / /
D) DNA/mutation/or/faulty/repair.
An/89-year-
old/female/patient/has/experienced/significant/decreases/in/her/mobility/and/stamina/during/a/3-
week/hospital/stay/for/the/treatment/of/a/femoral/head/fracture./Which/of/the/following/phenome
na/most/likely/accounts/for/the/patients/decrease/in/muscle/function
11. that/underlies/her/reduced/mobility?
A) Impaired/muscle/cell/metabolism/resulting/from/metaplasia
B) Dysplasia/as/a/consequence/of/inflammation/during/bone/remodeling
C) Disuse/atrophy/of/muscle/cells/during/a/prolonged/period/of/immobility
CLINICOPATHOLOGIC FOUNDATIONS OF
MEDICINE 7TH EDITION ( WITH ANSWER
KEY)
LATEST UPDATED EXAMINATION STUDY
GUIDE 2023
GUARANTEED GRADE A+
Chapter 1: Cell Adaptation, Injury and Death
Ischemia and other toxic injuries increase the accumulation of intracellular calcium as a result
1. of:
A) release of stored calcium from the mitochondria.
B) improved intracellular volume regulation.
C) decreased influx across the cell membrane.
D) attraction of calcium to fatty infiltrates.
The patient is found to have liver disease, resulting in the removal of a lobe of his liver.
2. Adaptation to the reduced size of the liver leads to _ of the remaining liver cells.
A) metaplasia
B) organ atrophy
C) compensatory hyperplasia
D) physiologic hypertrophy
A person eating peanuts starts choking and collapses. His airway obstruction is partially
cleared, but he remains hypoxic until he reaches the hospital. The prolonged cell hypoxia
3. caused a cerebral infarction and resulting _ in the brain.
A) caspase activation
B) coagulation necrosis
C) rapid phagocytosis
D) protein p53 deficiency
Bacteria and viruses cause cell damage by , which is unique from the intracellular
4. damage caused by other injurious agents.
A) disrupting the sodium/potassium ATPase pump
B) interrupting oxidative metabolism processes
C) replicating and producing continued injury
,TEST BANK FOR RUBIN’S PATHOLOGY:
CLINICOPATHOLOGIC FOUNDATIONS OF
MEDICINE 7TH EDITION ( WITH ANSWER
KEY)
LATEST UPDATED EXAMINATION STUDY
GUIDE 2023
GUARANTEED GRADE A+
D) decreasing protein synthesis and function
The patient has a prolonged interruption in arterial blood flow to his left kidney, causing
5. hypoxic cell injury and the release of free radicals. Free radicals damage cells by:
A) destroying phospholipids in the cell membrane.
B) altering the immune response of the cell.
C) disrupting calcium storage in the cell.
D) inactivation of enzymes and mitochondria.
,TEST BANK FOR RUBIN’S PATHOLOGY: CLI
/ / / / //
NICOPATHOLOGICFOUNDATIONS OF ME / / //
DICINE 7TH EDITION ( WITH ANSWER KEY)
/ / / / / //
LATEST UPDATED EXAMINATION STUDY G
/ / / //
UIDE 2023
/
GUARANTEED GRADE A+ / /
6. Injured/cells/have/impaired/flow/of/substances/through/the/cell/membrane/as/a/result/of:
A) increased/fat/load.
B) altered/permeability.
C) altered/glucose/utilization.
D) increased/surface/receptors.
7. Reversible/adaptive/intracellular/responses/are/initiated/by:
A) stimulus/overload.
B) genetic/mutations.
C) chemical/messengers.
D) mitochondrial/DNA.
8. Injured/cells/become/very/swollen/as/a/result/of:
A) increased/cell/protein/synthesis.
B) altered/cell/volume/regulation.
C) passive/entry/of/potassium/into/the/cell.
D) bleb/formation/in/the/plasma/membrane.
A/diabetic/patient/has/impaired/sensation,/circulation,/and/oxygenation/of/his/feet./He/steps/on/a/
piece/of/glass,/the/wound/does/not/heal,/and/the/area/tissue/becomes/necrotic./The/necrotic
9. cell/death/is/ characterized/by:
A) rapid/apoptosis.
B) cellular/rupture.
C) shrinkage/and/collapse.
D) chronic/inflammation.
A/99-year-old/woman/has/experienced/the/decline/of/cell/function/associated/with/age./A
10. group/of/theories/ of/cellular/aging/focus/on/programmed:
A) changes/with/genetic/influences.
B) elimination/of/cell/receptor/sites.
C) insufficient/telomerase/enzyme.
, TEST BANK FOR RUBIN’S PATHOLOGY: CLI
/ / / / //
NICOPATHOLOGICFOUNDATIONS OF ME / / //
DICINE 7TH EDITION ( WITH ANSWER KEY)
/ / / / / //
LATEST UPDATED EXAMINATION STUDY G
/ / / //
UIDE 2023
/
GUARANTEED GRADE A+ / /
D) DNA/mutation/or/faulty/repair.
An/89-year-
old/female/patient/has/experienced/significant/decreases/in/her/mobility/and/stamina/during/a/3-
week/hospital/stay/for/the/treatment/of/a/femoral/head/fracture./Which/of/the/following/phenome
na/most/likely/accounts/for/the/patients/decrease/in/muscle/function
11. that/underlies/her/reduced/mobility?
A) Impaired/muscle/cell/metabolism/resulting/from/metaplasia
B) Dysplasia/as/a/consequence/of/inflammation/during/bone/remodeling
C) Disuse/atrophy/of/muscle/cells/during/a/prolonged/period/of/immobility
