ESTUDYR
PHARM NURS 295 BYUI UPDATED EXAM WITH MOST TESTED
QUESTIONS AND ANSWERS | GRADED A+ | ASSURED SUCCESS WITH
DETAILED RATIONALES
1. Which of the following are considered the “6 Rights” of medication administration?
A. Drug, dose, route, time, patient, documentation
B. Drug, dose, route, patient, family, lab results
C. Drug, dose, route, time, nurse, documentation
D. Drug, dose, route, time, environment, patient
Answer: A. Drug, dose, route, time, patient, documentation
Rationale: The 6 Rights are fundamental for safe medication administration. Other options
include incorrect elements (family, nurse, environment, labs) that are not part of the standard 6
Rights.
2. Which of the following are considered parenteral routes of medication administration?
A. IV, IM, SC, topical, sublingual, intradermal, transdermal patch
B. Oral, rectal, sublingual
C. Buccal, oral, IV
D. Inhalation, topical, oral
Answer: A. IV, IM, SC, topical, sublingual, intradermal, transdermal patch
Rationale: Parenteral routes bypass the GI tract (IV, IM, SC, intradermal, sublingual,
transdermal). Oral and rectal routes are enteral, not parenteral.
3. What is the “first-pass effect” in enteral drug administration?
A. Drugs pass through GI tract → liver → systemic circulation, reducing bioavailability
B. Drugs are absorbed immediately into bloodstream without metabolism
C. Drugs are metabolized in the kidneys first
D. Drugs bypass the liver entirely
Answer: A. Drugs pass through GI tract → liver → systemic circulation, reducing
bioavailability
,ESTUDYR
Rationale: The first-pass effect occurs when orally or rectally administered drugs are
metabolized in the liver before reaching systemic circulation, which can reduce their
effectiveness.
4. Which of the following are oral medication forms?
A. Capsules, tablets, elixirs, syrups, suspensions
B. IV, IM, SC
C. Transdermal patches and intradermal
D. Sublingual and buccal only
Answer: A. Capsules, tablets, elixirs, syrups, suspensions
Rationale: Oral medications are ingested and absorbed through the GI tract. Other routes (IV,
transdermal, sublingual) bypass oral ingestion.
5. Buccal and sublingual medications are administered:
A. Inside the cheek or under the tongue for direct absorption into blood
B. Orally and swallowed
C. Rectally
D. Topically on skin
Answer: A. Inside the cheek or under the tongue for direct absorption into blood
Rationale: Buccal and sublingual routes allow rapid absorption into systemic circulation,
bypassing first-pass metabolism.
6. Rectal suppositories are used because:
A. They provide local or systemic effects and partially bypass the liver
B. They are absorbed faster than IV medications
C. They are preferred for all medications
D. They are less effective than oral tablets
Answer: A. They provide local or systemic effects and partially bypass the liver
Rationale: Rectal medications can be used for local or systemic effects and partially bypass
hepatic first-pass metabolism.
, ESTUDYR
7. A drug that is highly protein-bound has:
A. Longer duration of action due to slower release into tissues
B. Rapid metabolism
C. Immediate elimination
D. Short half-life
Answer: A. Longer duration of action due to slower release into tissues
Rationale: Protein-bound drugs are slowly released into tissues, prolonging duration of action.
Unbound drugs act faster and are eliminated more quickly.
8. A drug with a high therapeutic index (TI) means:
A. It has a large safety window and is less toxic to the patient
B. It is very toxic even in small doses
C. The dose must be monitored very closely
D. It is always ineffective
Answer: A. It has a large safety window and is less toxic to the patient
Rationale: High TI drugs are safer because effective doses are far from toxic doses. Low TI
drugs require careful monitoring.
9. A drug with a low therapeutic index (TI):
A. Has a narrow safety window and is more toxic
B. Is always safe in large doses
C. Has no need for monitoring
D. Is never used in adults
Answer: A. Has a narrow safety window and is more toxic
Rationale: Low TI drugs require careful monitoring of blood levels because effective and toxic
doses are close.
10. Enzyme inhibitors affect drug metabolism by:
PHARM NURS 295 BYUI UPDATED EXAM WITH MOST TESTED
QUESTIONS AND ANSWERS | GRADED A+ | ASSURED SUCCESS WITH
DETAILED RATIONALES
1. Which of the following are considered the “6 Rights” of medication administration?
A. Drug, dose, route, time, patient, documentation
B. Drug, dose, route, patient, family, lab results
C. Drug, dose, route, time, nurse, documentation
D. Drug, dose, route, time, environment, patient
Answer: A. Drug, dose, route, time, patient, documentation
Rationale: The 6 Rights are fundamental for safe medication administration. Other options
include incorrect elements (family, nurse, environment, labs) that are not part of the standard 6
Rights.
2. Which of the following are considered parenteral routes of medication administration?
A. IV, IM, SC, topical, sublingual, intradermal, transdermal patch
B. Oral, rectal, sublingual
C. Buccal, oral, IV
D. Inhalation, topical, oral
Answer: A. IV, IM, SC, topical, sublingual, intradermal, transdermal patch
Rationale: Parenteral routes bypass the GI tract (IV, IM, SC, intradermal, sublingual,
transdermal). Oral and rectal routes are enteral, not parenteral.
3. What is the “first-pass effect” in enteral drug administration?
A. Drugs pass through GI tract → liver → systemic circulation, reducing bioavailability
B. Drugs are absorbed immediately into bloodstream without metabolism
C. Drugs are metabolized in the kidneys first
D. Drugs bypass the liver entirely
Answer: A. Drugs pass through GI tract → liver → systemic circulation, reducing
bioavailability
,ESTUDYR
Rationale: The first-pass effect occurs when orally or rectally administered drugs are
metabolized in the liver before reaching systemic circulation, which can reduce their
effectiveness.
4. Which of the following are oral medication forms?
A. Capsules, tablets, elixirs, syrups, suspensions
B. IV, IM, SC
C. Transdermal patches and intradermal
D. Sublingual and buccal only
Answer: A. Capsules, tablets, elixirs, syrups, suspensions
Rationale: Oral medications are ingested and absorbed through the GI tract. Other routes (IV,
transdermal, sublingual) bypass oral ingestion.
5. Buccal and sublingual medications are administered:
A. Inside the cheek or under the tongue for direct absorption into blood
B. Orally and swallowed
C. Rectally
D. Topically on skin
Answer: A. Inside the cheek or under the tongue for direct absorption into blood
Rationale: Buccal and sublingual routes allow rapid absorption into systemic circulation,
bypassing first-pass metabolism.
6. Rectal suppositories are used because:
A. They provide local or systemic effects and partially bypass the liver
B. They are absorbed faster than IV medications
C. They are preferred for all medications
D. They are less effective than oral tablets
Answer: A. They provide local or systemic effects and partially bypass the liver
Rationale: Rectal medications can be used for local or systemic effects and partially bypass
hepatic first-pass metabolism.
, ESTUDYR
7. A drug that is highly protein-bound has:
A. Longer duration of action due to slower release into tissues
B. Rapid metabolism
C. Immediate elimination
D. Short half-life
Answer: A. Longer duration of action due to slower release into tissues
Rationale: Protein-bound drugs are slowly released into tissues, prolonging duration of action.
Unbound drugs act faster and are eliminated more quickly.
8. A drug with a high therapeutic index (TI) means:
A. It has a large safety window and is less toxic to the patient
B. It is very toxic even in small doses
C. The dose must be monitored very closely
D. It is always ineffective
Answer: A. It has a large safety window and is less toxic to the patient
Rationale: High TI drugs are safer because effective doses are far from toxic doses. Low TI
drugs require careful monitoring.
9. A drug with a low therapeutic index (TI):
A. Has a narrow safety window and is more toxic
B. Is always safe in large doses
C. Has no need for monitoring
D. Is never used in adults
Answer: A. Has a narrow safety window and is more toxic
Rationale: Low TI drugs require careful monitoring of blood levels because effective and toxic
doses are close.
10. Enzyme inhibitors affect drug metabolism by:
