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Which ABY is produced in the primary immune response? - Answer✅✅IgM
What is the CD marker that has receptor sheep RBCs (rosettes are formed)? -
Answer✅✅CD2
Which CD marker transmits signals to activate T cells? - Answer✅✅CD3
Which CD marker is a T helper cell co-receptor that binds MHC class 2 molecules? -
Answer✅✅CD4
Which CD marker is a T cytotoxic cell co-receptor that binds MHC class 1 molecules?
- Answer✅✅CD8
Which CD marker signals to regulate B cell development and maturation? -
Answer✅✅CD19
Which CD marker is a NK cell receptor for the Fc portion of IgG? - Answer✅✅CD16
, Which CD marker is a NK cell marker that helps support antibody production? -
Answer✅✅CD56
B cell maturation line - Answer✅✅Pro B
Pre B
Immature B
Mature B
Plasma cell
Memory B cell
In T cell maturation, is CD4 or CD8 present in the double negative stage? -
Answer✅✅No, neither are present
Which two CD markers are present in the double positive stage in T cell maturation?
- Answer✅✅CD4 & CD8
What is the function of T helper cells? - Answer✅✅Effector cells produce cytokines
What is the function of B cells & plasma cells? - Answer✅✅Antibody production
What is the function of cytotoxic T cell? - Answer✅✅Effector cells kill diseased cells
What is the function of natural killer cells? - Answer✅✅Kills diseased cells without
prior exposure
What are the two methods of killing for NK cells? - Answer✅✅ABY independent
cytotoxicity: occurs with decreased MHC Class 1 expression
ABY dependent cytotoxicity: recognition of Fc portion of the ABY
T cells interact with antigens with what? - Answer✅✅TCR
B cells interact with antigens with what? - Answer✅✅BCR
What are the antigen presenting cells? - Answer✅✅B cells, macrophages,
monocytes, dendritic cells
What are glycoproteins made by B cells? - Answer✅✅Immunoglobulins
Where are B cells located? - Answer✅✅Lymph nodes: cortex
Spleen: PALS region
What is the phagocyte binding region of IgG? - Answer✅✅Fc
Where does antigen independent lymphopoieses occur? - Answer✅✅Bone marrow
Which immunoglobulins have J chains? - Answer✅✅IgA