1/11/26, 5:28 PM NRNP 6566 WK1-5 Midterm Exam Questions & Answers | 100% Verified solutions |Questions with Correct Answers 2026 latest upd…
NRNP 6566 WK1-5 Midterm Exam Questions &
Answers | 100% Verified solutions |Questions with
Correct Answers 2026 latest update!!
Save
Terms in this set (38)
Describe cytochrome p450 system Cytochrome p450 system is a series of enzymes
used to metabolize medications
Inhibitors block metabolic activity from one or more CYP450
enzymes
Inducers increase CYP450 enzyme activity by increasing
enzyme synthesis
Describe effect on low and high Albumin is the plasma protein with the greatest
albumin levels on active drug levels capacity for binding drugs. Binding plasma proteins
especially for drugs that are highly affect drug distribution into tissues, because only
protein bound drug that is not bound is available to penetrate
tissues, bind to receptors, and exert activity. As free
drug leaves the blood stream, more bound drug is
released from binding sites.
Low albumin levels malnutrition, chronic illness
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, 1/11/26, 5:28 PM NRNP 6566 WK1-5 Midterm Exam Questions & Answers | 100% Verified solutions |Questions with Correct Answers 2026 latest upd…
Highly protein bound drugs can lead toxicity in patients with low albumin levels,
to example malnutrition or chronic illness. This is
because there are fewer than the normal sites for
the drug to bind
Describe the ways the hepatic first Alternative routes include:
pass effect- which is metabolism suppository
during first pass through the liver intravenous
intramuscular
inhalational aerosol
transdermal
sublingual
These allow drugs to bypass the first-pass effect
and be absorbed directly into systemic circulation
Be able to calculate creatinine Male = 140-age times weight in kilograms divided
clearance using Cockgraft Gault by serum creatinine times 72.
equation: Women = CRCL (male) times 0.85
Describe what determines the half life
frequency of drug administration plasma concentration
Be familiar with the beers criteria and Potentially Inappropriate Medication Use in Older
how to use it Adults
to call attention to medications that are most
commonly problematic and thus should be
avoided in older adults
Describe factors that affect low blood state (shock or arrest), contact time with
absorption GI tract too fast (diarrhea = cant absorb), delayed
stomach emptying (large meal = delayed
absorption)Drug- to drug or drug to food
interactions
https://quizlet.com/1129310776/nrnp-6566-wk1-5-midterm-exam-questions-answers-100-verified-solutions-questions-with-correct-answers-2026-lates… 2/10
NRNP 6566 WK1-5 Midterm Exam Questions &
Answers | 100% Verified solutions |Questions with
Correct Answers 2026 latest update!!
Save
Terms in this set (38)
Describe cytochrome p450 system Cytochrome p450 system is a series of enzymes
used to metabolize medications
Inhibitors block metabolic activity from one or more CYP450
enzymes
Inducers increase CYP450 enzyme activity by increasing
enzyme synthesis
Describe effect on low and high Albumin is the plasma protein with the greatest
albumin levels on active drug levels capacity for binding drugs. Binding plasma proteins
especially for drugs that are highly affect drug distribution into tissues, because only
protein bound drug that is not bound is available to penetrate
tissues, bind to receptors, and exert activity. As free
drug leaves the blood stream, more bound drug is
released from binding sites.
Low albumin levels malnutrition, chronic illness
https://quizlet.com/1129310776/nrnp-6566-wk1-5-midterm-exam-questions-answers-100-verified-solutions-questions-with-correct-answers-2026-lates… 1/10
, 1/11/26, 5:28 PM NRNP 6566 WK1-5 Midterm Exam Questions & Answers | 100% Verified solutions |Questions with Correct Answers 2026 latest upd…
Highly protein bound drugs can lead toxicity in patients with low albumin levels,
to example malnutrition or chronic illness. This is
because there are fewer than the normal sites for
the drug to bind
Describe the ways the hepatic first Alternative routes include:
pass effect- which is metabolism suppository
during first pass through the liver intravenous
intramuscular
inhalational aerosol
transdermal
sublingual
These allow drugs to bypass the first-pass effect
and be absorbed directly into systemic circulation
Be able to calculate creatinine Male = 140-age times weight in kilograms divided
clearance using Cockgraft Gault by serum creatinine times 72.
equation: Women = CRCL (male) times 0.85
Describe what determines the half life
frequency of drug administration plasma concentration
Be familiar with the beers criteria and Potentially Inappropriate Medication Use in Older
how to use it Adults
to call attention to medications that are most
commonly problematic and thus should be
avoided in older adults
Describe factors that affect low blood state (shock or arrest), contact time with
absorption GI tract too fast (diarrhea = cant absorb), delayed
stomach emptying (large meal = delayed
absorption)Drug- to drug or drug to food
interactions
https://quizlet.com/1129310776/nrnp-6566-wk1-5-midterm-exam-questions-answers-100-verified-solutions-questions-with-correct-answers-2026-lates… 2/10
