FULL TEST BANK FOR
LEHNE'S PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
NURSES AND PHYSICIAN ASSISTANTS 3RD EDITION
BY LAURA D. ROSENTHAL ,JACQUELINE ROSENJACK BURCHUM
ALL COMPLETE UNITS I : XXI | ALL CHAPTERS 1:92 | VERIFIED
ANSWERS
,TABLE OF CONTENTS
UNIT I: INTRODUCTION ................................................................................................................... 7
CHAPTER 1: PRESCRIPTIVE AUTHORITY ...................................................................................... 7
CHAPTER 2: RATIONAL DRUG SELECTION AND PRESCRIPTION WRITING................................. 11
CHAPTER 3: PROMOTING POSITIVE OUTCOMES OF DRUG THERAPY ...................................... 16
UNIT II: BASIC PRINCIPLES OF PHARMACOLOGY .......................................................................... 22
CHAPTER 4: PHARMACOKINETICS, PHARMACODYNAMICS, AND DRUG INTERACTIONS......... 22
CHAPTER 5: ADVERSE DRUG REACTIONS AND MEDICATION ERRORS...................................... 32
CHAPTER 6: INDIVIDUAL VARIATION IN DRUG RESPONSES ...................................................... 42
CHAPTER 7 GENETIC AND GENOMIC CONSIDERATIONS IN PHARMACOTHERAPEUTICS ......... 50
UNIT III: DRUG THERAPY ACROSS THE LIFE SPAN ......................................................................... 60
CHAPTER 8: DRUG THERAPY DURING PREGNANCY AND BREAST-FEEDING ............................. 60
CHAPTER 9: DRUG THERAPY IN PEDIATRIC PATIENTS ............................................................... 68
CHAPTER 10: DRUG THERAPY IN GERIATRIC ............................................................................. 76
UNIT IV: PERIPHERAL NERVOUS SYSTEM DRUGS ......................................................................... 86
CHAPTER 11: BASIC PRINCIPLES OF NEUROPHARMACOLOGY ................................................. 86
CHAPTER 12: PHYSIOLOGY OF THE PERIPHERAL NERVOUS SYSTEM ........................................ 92
CHAPTER 13: MUSCARINIC AGONISTS ...................................................................................... 99
CHAPTER 14 MUSCARINIC ANTAGONISTS .............................................................................. 105
CHAPTER 15: ADRENERGIC AGONISTS .................................................................................... 112
CHAPTER 16: ADRENERGIC ANTAGONISTS ............................................................................. 121
CHAPTER 17: INDIRECT-ACTING ANTIADRENERGIC AGENTS .................................................. 133
UNIT V: CENTRAL NERVOUS SYSTEM DRUGS.............................................................................. 141
CHAPTER 18: INTRODUCTION TO CENTRAL NERVOUS SYSTEM PHARMACOLOGY ................ 141
CHAPTER 19: DRUGS FOR PARKINSON'S DISEASE................................................................... 147
CHAPTER 20: DRUGS FOR ALZHEIMER'S DISEASE ................................................................... 154
CHAPTER 21: DRUGS FOR SEIZURE ......................................................................................... 162
UNIT VI: DRUGS FOR PAIN........................................................................................................... 177
CHAPTER 23: LOCAL ANESTHETICS ......................................................................................... 177
, CHAPTER 24: OPIOID ANALGESICS, OPIOID ANTAGONISTS, AND NONOPIOID CENTRALLY
ACTING ANALGESICS ............................................................................................................... 185
CHAPTER 25: DRUGS FOR HEADACHE..................................................................................... 196
UNIT VII: PSYCHOTHERAPEUTIC DRUGS ..................................................................................... 205
CHAPTER 26: ANTIPSYCHOTIC AGENTS AND THEIR USE IN SCHIZOPHRENIA ......................... 205
CHAPTER 27: ANTIDEPRESSANTS ............................................................................................ 216
CHAPTER 28: DRUGS FOR BIPOLAR DISORDER ....................................................................... 225
CHAPTER 29: SEDATIVE-HYPNOTIC DRUGS ............................................................................. 234
CHAPTER 30: MANAGEMENT OF ANXIETY DISORDERS .......................................................... 240
CHAPTER 31: CENTRAL NERVOUS SYSTEM STIMULANTS AND ATTENTION-
DEFICIT/HYPERACTIVITY DISORDER ........................................................................................ 248
UNIT VIII: SUBSTANCE USE DISORDERS....................................................................................... 256
CHAPTER 32: DRUG ABUSE I: BASIC CONSIDERATIONS .......................................................... 256
CHAPTER 33: DRUG ABUSE II: ALCOHOL ................................................................................. 263
CHAPTER 34: DRUG ABUSE III: NICOTINE AND SMOKING ...................................................... 272
CHAPTER 35: DRUG ABUSE IV: MAJOR DRUGS OF ABUSE OTHER THAN ALCOHOL AND
NICOTINE ................................................................................................................................. 279
CHAPTER 36: REVIEW OF HEMODYNAMICS ........................................................................... 293
UNIT IX: DRUGS THAT AFFECT THE HEART, BLOOD VESSELS, BLOOD, AND BLOOD VOLUME36.
REVIEW OF HEMODYNAMICS ..................................................................................................... 299
CHAPTER 37: DIURETICS ......................................................................................................... 299
CHAPTER 38: DRUGS ACTING ON THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM .......... 306
CHAPTER 39: CALCIUM CHANNEL BLOCKERS ......................................................................... 315
CHAPTER 40: VASODILATORS .................................................................................................. 320
CHAPTER 41: DRUGS FOR HYPERTENSION ............................................................................. 328
CHAPTER 42: DRUGS FOR HEART FAILURE .............................................................................. 342
CHAPTER 43: ANTIDYSRHYTHMIC DRUGS .............................................................................. 356
CHAPTER 44: PROPHYLAXIS OF ATHEROSCLEROTIC CARDIOVASCULAR DISEASE: DRUGS THAT
HELP NORMALIZE CHOLESTEROL AND TRIGLYCERIDE LEVELS ................................................ 371
CHAPTER 45: DRUGS FOR ANGINA PECTORIS ......................................................................... 384
, CHAPTER 46: ANTICOAGULANT, ANTIPLATELET, AND THROMBOLYTIC DRUGS ..................... 397
CHAPTER 47: DRUGS FOR DEFICIENCY ANEMIAS ................................................................... 410
UNIT X: DRUGS FOR ENDOCRINE DISORDERS............................................................................. 420
CHAPTER 48: DRUGS FOR DIABETES MELLITUS ...................................................................... 420
CHAPTER 49: DRUGS FOR THYROID DISORDERS .................................................................... 432
UNIT XI: WOMEN'S HEALTH ........................................................................................................ 442
CHAPTER 50: ESTROGENS AND PROGESTINS: BASIC PHARMACOLOGY AND
NONCONTRACEPTIVE APPLICATIONS ..................................................................................... 442
CHAPTER 51: BIRTH CONTROL ................................................................................................ 448
UNIT XII: MEN'S HEALTH ............................................................................................................. 459
CHAPTER 52: ANDROGENS ..................................................................................................... 459
CHAPTER 53: DRUGS FOR ERECTILE DYSFUNCTION AND BENIGN PROSTATIC HYPERPLASIA 467
UNIT XIII: ANTI-INFLAMMATORY, ANTIALLERGIC, AND IMMUNOLOGIC DRUGS ........................ 472
CHAPTER 54: REVIEW OF THE IMMUNE SYSTEM ................................................................... 472
CHAPTER 55: CHILDHOOD IMMUNIZATION............................................................................ 479
CHAPTER 56: ANTIHISTAMINES ............................................................................................... 490
CHAPTER 57: CYCLOOXYGENASE INHIBITORS: NONSTEROIDAL ANTI-INFLAMMATORY DRUGS
AND ACETAMINOPHEN ........................................................................................................... 499
CHAPTER 58: GLUCOCORTICOIDS IN NONENDOCRINE DISORDERS ....................................... 509
UNIT XIV: DRUGS FOR BONE AND JOINT DISORDERS ................................................................. 520
CHAPTER 59: DRUG THERAPY OF RHEUMATOID ARTHRITIS .................................................. 520
CHAPTER 60: DRUG THERAPY OF GOUT ................................................................................. 527
CHAPTER 61: DRUGS AFFECTING CALCIUM LEVELS AND BONE MINERALIZATION ................ 533
UNIT XV: RESPIRATORY TRACT DRUGS ........................................................................................ 544
CHAPTER 62: DRUGS FOR ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE .... 544
CHAPTER 63: DRUGS FOR ALLERGIC RHINITIS, COUGH, AND COLDS ..................................... 558
UNIT XVI: GASTROINTESTINAL DRUGS........................................................................................ 568
CHAPTER 64: DRUGS FOR PEPTIC ULCER DISEASE .................................................................. 568
CHAPTER 65: LAXATIVES ......................................................................................................... 577
CHAPTER 66: OTHER GASTROINTESTINAL DRUGS .................................................................. 587
LEHNE'S PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
NURSES AND PHYSICIAN ASSISTANTS 3RD EDITION
BY LAURA D. ROSENTHAL ,JACQUELINE ROSENJACK BURCHUM
ALL COMPLETE UNITS I : XXI | ALL CHAPTERS 1:92 | VERIFIED
ANSWERS
,TABLE OF CONTENTS
UNIT I: INTRODUCTION ................................................................................................................... 7
CHAPTER 1: PRESCRIPTIVE AUTHORITY ...................................................................................... 7
CHAPTER 2: RATIONAL DRUG SELECTION AND PRESCRIPTION WRITING................................. 11
CHAPTER 3: PROMOTING POSITIVE OUTCOMES OF DRUG THERAPY ...................................... 16
UNIT II: BASIC PRINCIPLES OF PHARMACOLOGY .......................................................................... 22
CHAPTER 4: PHARMACOKINETICS, PHARMACODYNAMICS, AND DRUG INTERACTIONS......... 22
CHAPTER 5: ADVERSE DRUG REACTIONS AND MEDICATION ERRORS...................................... 32
CHAPTER 6: INDIVIDUAL VARIATION IN DRUG RESPONSES ...................................................... 42
CHAPTER 7 GENETIC AND GENOMIC CONSIDERATIONS IN PHARMACOTHERAPEUTICS ......... 50
UNIT III: DRUG THERAPY ACROSS THE LIFE SPAN ......................................................................... 60
CHAPTER 8: DRUG THERAPY DURING PREGNANCY AND BREAST-FEEDING ............................. 60
CHAPTER 9: DRUG THERAPY IN PEDIATRIC PATIENTS ............................................................... 68
CHAPTER 10: DRUG THERAPY IN GERIATRIC ............................................................................. 76
UNIT IV: PERIPHERAL NERVOUS SYSTEM DRUGS ......................................................................... 86
CHAPTER 11: BASIC PRINCIPLES OF NEUROPHARMACOLOGY ................................................. 86
CHAPTER 12: PHYSIOLOGY OF THE PERIPHERAL NERVOUS SYSTEM ........................................ 92
CHAPTER 13: MUSCARINIC AGONISTS ...................................................................................... 99
CHAPTER 14 MUSCARINIC ANTAGONISTS .............................................................................. 105
CHAPTER 15: ADRENERGIC AGONISTS .................................................................................... 112
CHAPTER 16: ADRENERGIC ANTAGONISTS ............................................................................. 121
CHAPTER 17: INDIRECT-ACTING ANTIADRENERGIC AGENTS .................................................. 133
UNIT V: CENTRAL NERVOUS SYSTEM DRUGS.............................................................................. 141
CHAPTER 18: INTRODUCTION TO CENTRAL NERVOUS SYSTEM PHARMACOLOGY ................ 141
CHAPTER 19: DRUGS FOR PARKINSON'S DISEASE................................................................... 147
CHAPTER 20: DRUGS FOR ALZHEIMER'S DISEASE ................................................................... 154
CHAPTER 21: DRUGS FOR SEIZURE ......................................................................................... 162
UNIT VI: DRUGS FOR PAIN........................................................................................................... 177
CHAPTER 23: LOCAL ANESTHETICS ......................................................................................... 177
, CHAPTER 24: OPIOID ANALGESICS, OPIOID ANTAGONISTS, AND NONOPIOID CENTRALLY
ACTING ANALGESICS ............................................................................................................... 185
CHAPTER 25: DRUGS FOR HEADACHE..................................................................................... 196
UNIT VII: PSYCHOTHERAPEUTIC DRUGS ..................................................................................... 205
CHAPTER 26: ANTIPSYCHOTIC AGENTS AND THEIR USE IN SCHIZOPHRENIA ......................... 205
CHAPTER 27: ANTIDEPRESSANTS ............................................................................................ 216
CHAPTER 28: DRUGS FOR BIPOLAR DISORDER ....................................................................... 225
CHAPTER 29: SEDATIVE-HYPNOTIC DRUGS ............................................................................. 234
CHAPTER 30: MANAGEMENT OF ANXIETY DISORDERS .......................................................... 240
CHAPTER 31: CENTRAL NERVOUS SYSTEM STIMULANTS AND ATTENTION-
DEFICIT/HYPERACTIVITY DISORDER ........................................................................................ 248
UNIT VIII: SUBSTANCE USE DISORDERS....................................................................................... 256
CHAPTER 32: DRUG ABUSE I: BASIC CONSIDERATIONS .......................................................... 256
CHAPTER 33: DRUG ABUSE II: ALCOHOL ................................................................................. 263
CHAPTER 34: DRUG ABUSE III: NICOTINE AND SMOKING ...................................................... 272
CHAPTER 35: DRUG ABUSE IV: MAJOR DRUGS OF ABUSE OTHER THAN ALCOHOL AND
NICOTINE ................................................................................................................................. 279
CHAPTER 36: REVIEW OF HEMODYNAMICS ........................................................................... 293
UNIT IX: DRUGS THAT AFFECT THE HEART, BLOOD VESSELS, BLOOD, AND BLOOD VOLUME36.
REVIEW OF HEMODYNAMICS ..................................................................................................... 299
CHAPTER 37: DIURETICS ......................................................................................................... 299
CHAPTER 38: DRUGS ACTING ON THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM .......... 306
CHAPTER 39: CALCIUM CHANNEL BLOCKERS ......................................................................... 315
CHAPTER 40: VASODILATORS .................................................................................................. 320
CHAPTER 41: DRUGS FOR HYPERTENSION ............................................................................. 328
CHAPTER 42: DRUGS FOR HEART FAILURE .............................................................................. 342
CHAPTER 43: ANTIDYSRHYTHMIC DRUGS .............................................................................. 356
CHAPTER 44: PROPHYLAXIS OF ATHEROSCLEROTIC CARDIOVASCULAR DISEASE: DRUGS THAT
HELP NORMALIZE CHOLESTEROL AND TRIGLYCERIDE LEVELS ................................................ 371
CHAPTER 45: DRUGS FOR ANGINA PECTORIS ......................................................................... 384
, CHAPTER 46: ANTICOAGULANT, ANTIPLATELET, AND THROMBOLYTIC DRUGS ..................... 397
CHAPTER 47: DRUGS FOR DEFICIENCY ANEMIAS ................................................................... 410
UNIT X: DRUGS FOR ENDOCRINE DISORDERS............................................................................. 420
CHAPTER 48: DRUGS FOR DIABETES MELLITUS ...................................................................... 420
CHAPTER 49: DRUGS FOR THYROID DISORDERS .................................................................... 432
UNIT XI: WOMEN'S HEALTH ........................................................................................................ 442
CHAPTER 50: ESTROGENS AND PROGESTINS: BASIC PHARMACOLOGY AND
NONCONTRACEPTIVE APPLICATIONS ..................................................................................... 442
CHAPTER 51: BIRTH CONTROL ................................................................................................ 448
UNIT XII: MEN'S HEALTH ............................................................................................................. 459
CHAPTER 52: ANDROGENS ..................................................................................................... 459
CHAPTER 53: DRUGS FOR ERECTILE DYSFUNCTION AND BENIGN PROSTATIC HYPERPLASIA 467
UNIT XIII: ANTI-INFLAMMATORY, ANTIALLERGIC, AND IMMUNOLOGIC DRUGS ........................ 472
CHAPTER 54: REVIEW OF THE IMMUNE SYSTEM ................................................................... 472
CHAPTER 55: CHILDHOOD IMMUNIZATION............................................................................ 479
CHAPTER 56: ANTIHISTAMINES ............................................................................................... 490
CHAPTER 57: CYCLOOXYGENASE INHIBITORS: NONSTEROIDAL ANTI-INFLAMMATORY DRUGS
AND ACETAMINOPHEN ........................................................................................................... 499
CHAPTER 58: GLUCOCORTICOIDS IN NONENDOCRINE DISORDERS ....................................... 509
UNIT XIV: DRUGS FOR BONE AND JOINT DISORDERS ................................................................. 520
CHAPTER 59: DRUG THERAPY OF RHEUMATOID ARTHRITIS .................................................. 520
CHAPTER 60: DRUG THERAPY OF GOUT ................................................................................. 527
CHAPTER 61: DRUGS AFFECTING CALCIUM LEVELS AND BONE MINERALIZATION ................ 533
UNIT XV: RESPIRATORY TRACT DRUGS ........................................................................................ 544
CHAPTER 62: DRUGS FOR ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE .... 544
CHAPTER 63: DRUGS FOR ALLERGIC RHINITIS, COUGH, AND COLDS ..................................... 558
UNIT XVI: GASTROINTESTINAL DRUGS........................................................................................ 568
CHAPTER 64: DRUGS FOR PEPTIC ULCER DISEASE .................................................................. 568
CHAPTER 65: LAXATIVES ......................................................................................................... 577
CHAPTER 66: OTHER GASTROINTESTINAL DRUGS .................................................................. 587
