( Neuropharmacology– Autonomic Nervous System (ANS)
Pharmacology)
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1. The part of the nervous system that increases HR, cardiac output, blood pressure,
bronchodilation, and pupil dilation is:
A) Parasympathetic nervous system
B) Sympathetic nervous system
C) Somatic motor system
D) Enteric nervous system
Rationale: The SNS controls “fight-or-flight” responses.
2. The part of the nervous system that slows HR, increases gastric secretions, and causes
bowel/bladder emptying is:
A) Parasympathetic nervous system
B) Sympathetic nervous system
C) Somatic motor system
D) Central nervous system
Rationale: The PNS controls “rest-and-digest” functions.
3. A substance that binds to a receptor and initiates a physiological response is called a:
A) Antagonist
B) Agonist
C) Modulator
D) Inhibitor
Rationale: An agonist activates a receptor to produce a response.
, 4. Receptors that mediate responses to norepinephrine and epinephrine are:
A) Cholinergic receptors
B) Adrenergic receptors
C) Nicotinic receptors
D) Muscarinic receptors
Rationale: Adrenergic receptors respond to NE/Epi in the SNS.
5. The neurotransmitter most associated with the parasympathetic nervous system is:
A) Acetylcholine (ACh)
B) Dopamine
C) Epinephrine
D) Norepinephrine
Rationale: ACh is released at parasympathetic target organs.
6. The drug class that prevents breakdown of ACh by acetylcholinesterase is:
A) Cholinesterase inhibitors
B) Muscarinic antagonists
C) Adrenergic agonists
D) Adrenergic antagonists
Rationale: This increases ACh at cholinergic receptors.
7. What is the antidote for cholinesterase inhibitor (organophosphate) poisoning?
A) Atropine
B) Bethanechol
C) Epinephrine
D) Pyridostigmine
Rationale: Atropine blocks muscarinic effects of excess ACh.
8. Which drug treats urinary retention by binding to muscarinic receptors?
A) Atropine
B) Bethanechol (Urecholine)
C) Pyridostigmine