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Examen

2025/2026 AG-ACNP Endocrine Exam Guide – 100 Verified Q&As | Diabetes, Thyroid, SIADH, DI, Adrenal Disorders, Meds & Labs

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This detailed, high-yield endocrine review for the 2025/2026 AG-ACNP certification exam delivers 100 advanced board-style questions with 100% accurate answers, crafted to deepen understanding of complex endocrine conditions and sharpen exam readiness. Aligned with the latest AACN and ANCC exam blueprints, this guide covers essential acute care knowledge every Adult-Gerontology Acute Care Nurse Practitioner must master. The document explores a comprehensive range of endocrine topics: Diabetes Mellitus (Type 1 & 2): pathophysiology, diagnostic markers, treatment regimens, complications like DKA and HHNK, and medication classes (e.g., metformin, sulfonylureas, glinides, TZDs) Insulin protocols & glucose emergencies: split-dose regimens, somogyi effect vs dawn phenomenon, insulin bolus/drip therapy in crisis care Thyroid Disorders: Graves' disease, thyroid storm management, hypothyroidism (Hashimoto’s), myxedema coma, and related medications Adrenal Pathologies: Addison’s disease, Cushing’s syndrome, dexamethasone suppression testing, steroid-related triads, and lab interpretation Pituitary & Posterior Pituitary Disorders: SIADH, Diabetes Insipidus (central vs nephrogenic), diagnostic strategies (urine osmolality, sodium handling), and treatments like DDAVP Pheochromocytoma: recognition, catecholamine-driven S/S, diagnostic labs (metanephrines), and surgical prep with alpha-blockers Medication Effects: Endocrine side effects of common drugs (e.g., statins, lithium, ASA), black box warnings, and emergency considerations Whether you're prepping for boards, refreshing clinical acumen, or teaching endocrine pathophysiology, this document provides a structured, up-to-date, and practice-oriented reference ideal for success in acute care settings. Who this document is for: AG-ACNP students in MSN or DNP programs needing focused endocrine mastery Nurse practitioner candidates preparing for AACN or ANCC acute care board certification Advanced practice faculty and preceptors using endocrine case-based review for exam or clinical instruction Practicing NPs or residents in critical care, internal medicine, or hospitalist roles managing endocrine emergencies Keywords: AGACNP endocrine review, 2025 board prep, diabetes type 1 and 2, DKA management, HHNK, insulin dosing, hypothyroidism, thyroid storm, Addison’s disease, Cushing’s labs, pheochromocytoma symptoms, SIADH labs, DI treatment, metformin mechanism, levothyroxine dosing, dexamethasone suppression test, adrenergic antagonist, endocrine crisis

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Subido en
29 de julio de 2025
Número de páginas
37
Escrito en
2024/2025
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Examen
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AG-ACNP Boards – Endocrine 2025/2026
Exam Questions and Correct Answers |
New Update


Serotonin Syndrome - 🧠 ANSWER ✔✔*Similar to NMS but caused by

serotinergic medications, and has HYPERreflexive muscle activity and clonus




*onset <12h




*caused by combination of serotinergic drugs or overdose on one drug




*treated with Cyproheptadine if drug withdrawal does not produce symptom

improvement

,Malignant hyperthermia - 🧠 ANSWER ✔✔*most common triggering agents =

volatile anesthetic gases, such as halothane, sevoflurane, desflurane, isoflurane,

enflurane




OR




*depolarizing muscle relaxants suxamethonium and decamethonium used

primarily in general anesthesia




-->Remember!! Sux absolutely contraindicated in hyperkalemia


ADH - 🧠 ANSWER ✔✔antidiuretic hormone (vasopressin)


-causes migration of aquaporins

-controls WATER concentration


Aldosterone - 🧠 ANSWER ✔✔-controls sodium/potassium concentration and

hydrogen ion secretion

,Diabetes (Type I) - 🧠 ANSWER ✔✔*Most common in adolescents by may occur

in adulthood, often following viral illness




*Selective autoimmune mediated destruction of the pancreatic Beta cells resulting

in absolute lack of insulin production.

-will not have C- peptide present in blood--substance produced when pro-insulin is

cleaved to form active insulin




*strongly associated with human leukocyte antigens with Islet cell antibodies

found in approximately 90% of patients within 1st year of diagnosis




*Marked by development of ketosis d/t absolute lack of insulin

-causes body to break down fatty acids for energy production


S/S of Type I Diabetes - 🧠 ANSWER ✔✔*3Ps: Polyuria, Polydipsia, Polyphagia




-nocturnal enuresis

-weight loss

COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
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, -weakness/fatigue


differential for unplanned weight loss - 🧠 ANSWER ✔✔-DM1




-cancer




-hyperthyroidism




-HIV




-TB


Lab/Diagnostics of Type I DM - 🧠 ANSWER ✔✔Random plasma glucose >200




Serum fasting blood sugar >126 on 2 separate occasions




ketonemia or ketonuria or both


Impaired glucose tolerance (pre-diabetic) - 🧠 ANSWER ✔✔FBG >100 BUT < 125
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