Ceutics Verified Multiple Choice and Conceptual Actual
Exam Questions Reviewed 100% Correct Detailed Answers
>> Guaranteed Pass!!Current Update
If a drug is formulated in a solution, sus-
pension and a tablet, which would have
the best chemical stability?
tablet
-solution
-suspension
-tablets
What are the two most common oral sol-
tablets and capsules
id dosage forms?
-Optimize the absorption rate of the drug
-Increase the ease of administration by
the patient
solid dosage forms are designed to do -Control the rate and site of drug absorp-
what five things? tion
-Mask the taste of a therapeutic agent
-Improve the chemical stability of the
drug
list the types of solid dosage form(s) for
the following route of administration: tablets, capsules, poder, granules
Oral
list the types of solid dosage form(s) for
buccal, sublingual tabs, films, troches,
the following route of administration:
lozenges
transmucosal
list the types of solid dosage form(s) for
the following route of administration: nasal powder
nasal
list the types of solid dosage form(s) for
the following route of administration: suppositories
rectal
list the types of solid dosage form(s) for
the following route of administration: vag tabs, suppositories, inserts
vaginal
list the types of solid dosage form(s) for
the following route of administration: urethral suppositoreis, mciropellets
urethral
, Ceutics Verified Multiple Choice and Conceptual Actual
Exam Questions Reviewed 100% Correct Detailed Answers
>> Guaranteed Pass!!Current Update
list the types of solid dosage form(s) for
the following route of administration: dry podwer inhalers, caps, powder
inhalation
list the types of solid dosage form(s) for
the following route of administration: dusting poders
dermal
list the types of solid dosage form(s)
for the following route of administration: nasal dry powders
nasal
list the types of solid dosage form(s) for
the following route of administration: devices
implants
-increased chemical and physical stabil-
ity (solid dosage forms have the longest
shelf life)
-less prone to microbial contamination
-ease of packaging, storage, and dis-
What are the advantages of solid dosage
pensing
forms?
-convenience and accurate dosing
-little or no taste or smell of the drug
(masking)
-can be modified for modified/controlled
drug release
-solubility (drug must dissolve from the
solid dosage from)
-not suitable for some patients (pediatric
and geriatric, patients who have difficulty
swallowing - dysphagia)
-solid dosage forms (as is) are not suit-
four Limitations of solid dosage forms
able for some routes of administration
(injectable (IV), transdermal, ophthalmic,
otic)
-some drug lose their activity in solid
form (therapeutic proteins and several
biological products)
Drug particles in some solid products are
often "micronized." This process increas-
, Ceutics Verified Multiple Choice and Conceptual Actual
Exam Questions Reviewed 100% Correct Detailed Answers
>> Guaranteed Pass!!Current Update
es the?
a) solubility of the drug
b) particle size of the drug c) dissolution rate of the drug
c) dissolution rate of the drug
d) shelf life of the drug product
-purity (efficacy and safety)
-organoleptic properties (color, odor, and
taste)
-the presence of polymorphs (crystal
forms)
-surface properties (wettability)
What are the five solid state properties?
-particle size and size distribution
(monodisperse vs polydisperse). This af-
fects the surface area, surface ener-
gy, hygroscopicity, flow properties, bulk,
tapped density, and compression proper-
ties
amorphous - faster dissolution rate, high-
er solubility
Differences between crystalline and crystalline - chemically more stable
amorphous crystal forms? crystalline is chemically more stable, but
amorphous has a faster dissolution rate
and higher solubility
crystalline has large peaces, while amor-
Explain the differences in X-ray diffrac-
phous has mores of a curve with small
tion in crystalline and amorphous forms
peaks
what is the function of a wetting agent in
solid dosage forms?
a) increase the diffusion rate of the drug
b) increase the solubility of the drug d) increase contact between drug parti-
c) increase the concentration gradient of cles and liquid
the drug
d) Increase contact between drug parti-
cles and liquid
what is a contact angle used to mea-
the wet ability of a solid
sure?
, Ceutics Verified Multiple Choice and Conceptual Actual
Exam Questions Reviewed 100% Correct Detailed Answers
>> Guaranteed Pass!!Current Update
characteristics of contact angle greater
hydrophobic surface, poor wetting
than 90 degrees
characteristics of a contact angle less
hydrophillic surface, good wetting
than 90 degrees
a hygroscopic drug is one that:
1) dose not dissolve in wate
2) hydrolyses rapidly in water c) adsorbs moisture from the environ-
3) adsorbs moisture from the environ- ment
ment
4) is prone to microbial growth
the property of a material that takes
moisture out of the air/ ability of a sub- hygroscopicity
stance to absorb moisture
-stability issues
-physical changes
What problems of a drug are due to hy-
-dosing accuracy
groscopicity?
-microbial growth
-packing challenges
-moisture-resistance excipients
-incorporate desiccants or moisture bar-
What are some methods to prevent prob- riers
lem due to hygroscopicity? -appropriate packaging materials
-implement appropriate storage and han-
dling practice
diameter of equivalent sphere- assigned
to an irregular particle is that same as
How are particles in drugs measured? that of a sphere that behaves identical-
ly when both are exposed to the same
process
equivalent spherical diameter:
sphere of same minimum length
dmin
equivalent spherical diameter:
sphere of same weight
dw
equivalent spherical diameter:
sphere of same volume
dv
Exam Questions Reviewed 100% Correct Detailed Answers
>> Guaranteed Pass!!Current Update
If a drug is formulated in a solution, sus-
pension and a tablet, which would have
the best chemical stability?
tablet
-solution
-suspension
-tablets
What are the two most common oral sol-
tablets and capsules
id dosage forms?
-Optimize the absorption rate of the drug
-Increase the ease of administration by
the patient
solid dosage forms are designed to do -Control the rate and site of drug absorp-
what five things? tion
-Mask the taste of a therapeutic agent
-Improve the chemical stability of the
drug
list the types of solid dosage form(s) for
the following route of administration: tablets, capsules, poder, granules
Oral
list the types of solid dosage form(s) for
buccal, sublingual tabs, films, troches,
the following route of administration:
lozenges
transmucosal
list the types of solid dosage form(s) for
the following route of administration: nasal powder
nasal
list the types of solid dosage form(s) for
the following route of administration: suppositories
rectal
list the types of solid dosage form(s) for
the following route of administration: vag tabs, suppositories, inserts
vaginal
list the types of solid dosage form(s) for
the following route of administration: urethral suppositoreis, mciropellets
urethral
, Ceutics Verified Multiple Choice and Conceptual Actual
Exam Questions Reviewed 100% Correct Detailed Answers
>> Guaranteed Pass!!Current Update
list the types of solid dosage form(s) for
the following route of administration: dry podwer inhalers, caps, powder
inhalation
list the types of solid dosage form(s) for
the following route of administration: dusting poders
dermal
list the types of solid dosage form(s)
for the following route of administration: nasal dry powders
nasal
list the types of solid dosage form(s) for
the following route of administration: devices
implants
-increased chemical and physical stabil-
ity (solid dosage forms have the longest
shelf life)
-less prone to microbial contamination
-ease of packaging, storage, and dis-
What are the advantages of solid dosage
pensing
forms?
-convenience and accurate dosing
-little or no taste or smell of the drug
(masking)
-can be modified for modified/controlled
drug release
-solubility (drug must dissolve from the
solid dosage from)
-not suitable for some patients (pediatric
and geriatric, patients who have difficulty
swallowing - dysphagia)
-solid dosage forms (as is) are not suit-
four Limitations of solid dosage forms
able for some routes of administration
(injectable (IV), transdermal, ophthalmic,
otic)
-some drug lose their activity in solid
form (therapeutic proteins and several
biological products)
Drug particles in some solid products are
often "micronized." This process increas-
, Ceutics Verified Multiple Choice and Conceptual Actual
Exam Questions Reviewed 100% Correct Detailed Answers
>> Guaranteed Pass!!Current Update
es the?
a) solubility of the drug
b) particle size of the drug c) dissolution rate of the drug
c) dissolution rate of the drug
d) shelf life of the drug product
-purity (efficacy and safety)
-organoleptic properties (color, odor, and
taste)
-the presence of polymorphs (crystal
forms)
-surface properties (wettability)
What are the five solid state properties?
-particle size and size distribution
(monodisperse vs polydisperse). This af-
fects the surface area, surface ener-
gy, hygroscopicity, flow properties, bulk,
tapped density, and compression proper-
ties
amorphous - faster dissolution rate, high-
er solubility
Differences between crystalline and crystalline - chemically more stable
amorphous crystal forms? crystalline is chemically more stable, but
amorphous has a faster dissolution rate
and higher solubility
crystalline has large peaces, while amor-
Explain the differences in X-ray diffrac-
phous has mores of a curve with small
tion in crystalline and amorphous forms
peaks
what is the function of a wetting agent in
solid dosage forms?
a) increase the diffusion rate of the drug
b) increase the solubility of the drug d) increase contact between drug parti-
c) increase the concentration gradient of cles and liquid
the drug
d) Increase contact between drug parti-
cles and liquid
what is a contact angle used to mea-
the wet ability of a solid
sure?
, Ceutics Verified Multiple Choice and Conceptual Actual
Exam Questions Reviewed 100% Correct Detailed Answers
>> Guaranteed Pass!!Current Update
characteristics of contact angle greater
hydrophobic surface, poor wetting
than 90 degrees
characteristics of a contact angle less
hydrophillic surface, good wetting
than 90 degrees
a hygroscopic drug is one that:
1) dose not dissolve in wate
2) hydrolyses rapidly in water c) adsorbs moisture from the environ-
3) adsorbs moisture from the environ- ment
ment
4) is prone to microbial growth
the property of a material that takes
moisture out of the air/ ability of a sub- hygroscopicity
stance to absorb moisture
-stability issues
-physical changes
What problems of a drug are due to hy-
-dosing accuracy
groscopicity?
-microbial growth
-packing challenges
-moisture-resistance excipients
-incorporate desiccants or moisture bar-
What are some methods to prevent prob- riers
lem due to hygroscopicity? -appropriate packaging materials
-implement appropriate storage and han-
dling practice
diameter of equivalent sphere- assigned
to an irregular particle is that same as
How are particles in drugs measured? that of a sphere that behaves identical-
ly when both are exposed to the same
process
equivalent spherical diameter:
sphere of same minimum length
dmin
equivalent spherical diameter:
sphere of same weight
dw
equivalent spherical diameter:
sphere of same volume
dv
