,
, MOLECULAR BIOLOGY OF THE CELL, SIXTH EDITION
g g g g g g
CHAPTER 1: CELLS AND GENOMES
g g g g g
© gGarland gScience g2015
1 Scientists gdiscover gmore gthan gten gthousand gnew gspecies gof gliving gorganisms gevery gyear.
g What gis gshared gbetween gall gof gthese gorganisms?
A. They gare gmade gof gcells, gwhose gnuclei genclose gtheir gDNA.
B. They gobtain gtheir genergy gfrom gsunlight.
C. They gproduce gand guse gadenosine gtriphosphate g(ATP).
D. Their ggenome gcontains gat gleast g1000 ggenes.
E. All gof gthe gabove.
2 All gcells g…
A. have gmembrane gtransport gproteins.
B. synthesize gproteins gon gthe gribosome.
C. replicate gtheir ggenome gby gDNA gpolymerization.
D. transcribe gtheir ggenetic ginformation gby gRNA gpolymerization.
E. All gof gthe gabove.
3 Imagine ga gsegment gof gDNA g(within ga ggene) gencoding ga gcertain gamount gof ginformation
gin gits gnucleotide gsequence. gWhen gthis gsegment gis gfully gtranscribed ginto gmRNA gand gthen
gtranslated ginto gprotein, gin ggeneral, g…
A. the gprotein gsequence gwould gcarry gmore ginformation gcompared gto gthe gDNA gand
gmRNA gsequences, gbecause gits galphabet ghas g20 gletters.
g B. g the gprotein gsequence gwould gcarry gless ginformation gcompared gto gthe gDNA gand
gmRNA gsequences, gbecause gseveral gcodons gcan gcorrespond gto gone gamino gacid.
C. the gamount gof ginformation gin gthe gmRNA gsequence gis glower, gbecause gthe gmRNA ghas
gbeen gtranscribed gusing gonly gone gof gthe gDNA gstrands gas gthe gtemplate.
D. the gamount gof ginformation gin gthe gmRNA gsequence gis ghigher, gbecause gseveral gmRNA
gmolecules gcan gbe gtranscribed gfrom gone gDNA gmolecule.
4 Which gof gthe gfollowing gprocesses gthat ghappens ginside ga gcell gDOES gNOT gnormally
grequire gconsumption gof gfree genergy gby gthe gcell?
, A. Replication gof gthe ggenetic gmaterial
B. Import gof gnutrients gfrom gthe genvironment
C. Diffusion gof gsmall gmolecules gwithin gthe gcell
D. Regulation gof ggene gexpression
E. Synthesis gof genzymes gthat gcatalyze gcellular greactions
5 Which gof gthe gfollowing gwould gyou gNg OT gexpect gto gfind gin ga gbacterial gcell?
A. Swimming gusing gflagella
B. Having ga gcell gwall garound gthe gplasma gmembrane
g C. g ATP gproduction gin gmitochondria
D. Protein gproduction gon gthe gribosome
E. Sexual gexchange gof gDNA gwith gother gbacteria
6 To gtrace gfamily grelationships gbetween gdistantly grelated gorganisms gsuch gas ghumans,
galgae, gbacteria, gand garchaea, gone gshould gcompare gtheir ggenomes gin gregions g…
A. that gevolve grapidly.
B. that ghave ga ghigher gmutation grate.
C. that gcode gfor gproteins.
D. where gmutations gare ghardly gtolerated.
E. where gmost gmutations gare gselectively gneutral.
7 Laboratory gstrains gof gthe gmodel gorganism gEscherichia gcoli gthat gare gresistant gto
gantibiotics gare gvery goften gused gin gresearch glaboratories gas gwell gas gin gthe gbiotechnology gindustry.
g If gcultures g of gsuch gbacteria gwere gallowed gto gcontaminate gthe genvironment guncontrollably, git gis
gpossible gthat g at gsome gpoint, gpathogenic gbacteria gsuch gas gNeisseria gmeningitidis g(which gcauses
gmeningitis gand gcan gcause gdeath, gespecially gin gchildren) gcould gacquire gthe gsame gantibiotic-
resistance ggene, g causing ga gmeningitis goutbreak gthat gis gdifficult gto gtreat. gIn gthis gscenario, gwhich
gof gthe gfollowing gmechanisms gis ga gmore glikely gsource gof gthe gantibiotic-resistance ggene gin gN.
gmeningitidis?
A. Random gnew ggene ggeneration
B. Intragenic gmutation
C. Gene gduplication
D. DNA gsegment gshuffling
E. Horizontal ggene gtransfer
8 A gvirus g…
A. is ga gtype gof gcell.
, MOLECULAR BIOLOGY OF THE CELL, SIXTH EDITION
g g g g g g
CHAPTER 1: CELLS AND GENOMES
g g g g g
© gGarland gScience g2015
1 Scientists gdiscover gmore gthan gten gthousand gnew gspecies gof gliving gorganisms gevery gyear.
g What gis gshared gbetween gall gof gthese gorganisms?
A. They gare gmade gof gcells, gwhose gnuclei genclose gtheir gDNA.
B. They gobtain gtheir genergy gfrom gsunlight.
C. They gproduce gand guse gadenosine gtriphosphate g(ATP).
D. Their ggenome gcontains gat gleast g1000 ggenes.
E. All gof gthe gabove.
2 All gcells g…
A. have gmembrane gtransport gproteins.
B. synthesize gproteins gon gthe gribosome.
C. replicate gtheir ggenome gby gDNA gpolymerization.
D. transcribe gtheir ggenetic ginformation gby gRNA gpolymerization.
E. All gof gthe gabove.
3 Imagine ga gsegment gof gDNA g(within ga ggene) gencoding ga gcertain gamount gof ginformation
gin gits gnucleotide gsequence. gWhen gthis gsegment gis gfully gtranscribed ginto gmRNA gand gthen
gtranslated ginto gprotein, gin ggeneral, g…
A. the gprotein gsequence gwould gcarry gmore ginformation gcompared gto gthe gDNA gand
gmRNA gsequences, gbecause gits galphabet ghas g20 gletters.
g B. g the gprotein gsequence gwould gcarry gless ginformation gcompared gto gthe gDNA gand
gmRNA gsequences, gbecause gseveral gcodons gcan gcorrespond gto gone gamino gacid.
C. the gamount gof ginformation gin gthe gmRNA gsequence gis glower, gbecause gthe gmRNA ghas
gbeen gtranscribed gusing gonly gone gof gthe gDNA gstrands gas gthe gtemplate.
D. the gamount gof ginformation gin gthe gmRNA gsequence gis ghigher, gbecause gseveral gmRNA
gmolecules gcan gbe gtranscribed gfrom gone gDNA gmolecule.
4 Which gof gthe gfollowing gprocesses gthat ghappens ginside ga gcell gDOES gNOT gnormally
grequire gconsumption gof gfree genergy gby gthe gcell?
, A. Replication gof gthe ggenetic gmaterial
B. Import gof gnutrients gfrom gthe genvironment
C. Diffusion gof gsmall gmolecules gwithin gthe gcell
D. Regulation gof ggene gexpression
E. Synthesis gof genzymes gthat gcatalyze gcellular greactions
5 Which gof gthe gfollowing gwould gyou gNg OT gexpect gto gfind gin ga gbacterial gcell?
A. Swimming gusing gflagella
B. Having ga gcell gwall garound gthe gplasma gmembrane
g C. g ATP gproduction gin gmitochondria
D. Protein gproduction gon gthe gribosome
E. Sexual gexchange gof gDNA gwith gother gbacteria
6 To gtrace gfamily grelationships gbetween gdistantly grelated gorganisms gsuch gas ghumans,
galgae, gbacteria, gand garchaea, gone gshould gcompare gtheir ggenomes gin gregions g…
A. that gevolve grapidly.
B. that ghave ga ghigher gmutation grate.
C. that gcode gfor gproteins.
D. where gmutations gare ghardly gtolerated.
E. where gmost gmutations gare gselectively gneutral.
7 Laboratory gstrains gof gthe gmodel gorganism gEscherichia gcoli gthat gare gresistant gto
gantibiotics gare gvery goften gused gin gresearch glaboratories gas gwell gas gin gthe gbiotechnology gindustry.
g If gcultures g of gsuch gbacteria gwere gallowed gto gcontaminate gthe genvironment guncontrollably, git gis
gpossible gthat g at gsome gpoint, gpathogenic gbacteria gsuch gas gNeisseria gmeningitidis g(which gcauses
gmeningitis gand gcan gcause gdeath, gespecially gin gchildren) gcould gacquire gthe gsame gantibiotic-
resistance ggene, g causing ga gmeningitis goutbreak gthat gis gdifficult gto gtreat. gIn gthis gscenario, gwhich
gof gthe gfollowing gmechanisms gis ga gmore glikely gsource gof gthe gantibiotic-resistance ggene gin gN.
gmeningitidis?
A. Random gnew ggene ggeneration
B. Intragenic gmutation
C. Gene gduplication
D. DNA gsegment gshuffling
E. Horizontal ggene gtransfer
8 A gvirus g…
A. is ga gtype gof gcell.
