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Summary "Advanced Human Bioscience: Key Concepts in Physiology, Genetics, and Disease Mechanisms"

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This document provides a comprehensive summary of Advanced Human Bioscience (HUBS1416), covering essential topics such as cell biology, metabolism, immunology, genetics, neuroscience, and pathology. It explores key biological processes, including DNA replication, gene expression, enzymatic reactions, homeostasis, immune response, and disease mechanisms. Additionally, it discusses the role of the cardiovascular and respiratory systems, microbiology, pharmacology, and human development, highlighting their relevance in medical and biomedical sciences. The document serves as a foundational guide for students and professionals in health sciences, biotechnology, and clinical research, offering insights into the biological systems that sustain life and contribute to disease progression.

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# Advanced Human Bioscience (HUBS1416) - 2025 Summary



Cover Page

Advanced Human Bioscience (HUBS1416) - 2025

Course Summary & Key Concepts

Author: DAVID KAMAU
Institution: KIRINYAGA UNIVERSITY
Date: March 2025



Table of Contents

1. Introduction

2. Cellular and Molecular Biology

3. Human Physiology and Homeostasis

4. Biochemistry and Metabolism

5. Immunology and Disease Pathophysiology

6. Human Genetics and Genomics

7. Microbiology and Infectious Diseases

8. Pharmacology and Toxicology

9. Neuroscience and Brain Function

10. Cardiovascular and Respiratory Systems

11. Human Development and Aging

12. Conclusion

13. Review Questions and Answers



Content Page (Sample Section)

1. Introduction

Advanced Human Bioscience (HUBS1416) explores the biological systems that sustain human life,
integrating key topics from anatomy, physiology, biochemistry, genetics, immunology, and pathology.
This document provides a structured overview of fundamental concepts, helping students understand
the intricate mechanisms behind human health and disease.

, 2. Cellular and Molecular Biology

 Structure and function of eukaryotic cells, including organelles.

 DNA replication, transcription, and translation.

 Cell cycle regulation, mitosis, and apoptosis.

 Cellular communication and signal transduction pathways.

3. Human Physiology and Homeostasis

 Mechanisms of homeostasis and feedback control systems.

 Nervous system regulation (CNS & PNS).

 Endocrine system and hormone regulation.

 Cardiovascular and respiratory system integration.



Review Questions and Answers

1. What is the primary function of homeostasis in the human body?

Answer: Homeostasis maintains a stable internal environment by regulating physiological processes
such as temperature, pH, and fluid balance.

2. What are the key differences between prokaryotic and eukaryotic cells?

Answer: Eukaryotic cells have a nucleus and membrane-bound organelles, while prokaryotic cells lack a
nucleus and have simpler structures.

3. How does the nervous system regulate bodily functions?

Answer: The nervous system controls voluntary and involuntary actions through the central (CNS) and
peripheral (PNS) nervous systems, using neurotransmitters for communication.

4. What role does ATP play in cellular metabolism?

Answer: ATP (adenosine triphosphate) provides energy for cellular processes, including muscle
contraction, nerve signaling, and biochemical reactions.

5. What is the function of DNA replication?

Answer: DNA replication ensures genetic information is accurately copied and passed on to new cells
during cell division.

6. How do antibodies help fight infections?

Answer: Antibodies recognize and neutralize pathogens by binding to antigens and triggering immune
responses.

7. What is the significance of the blood-brain barrier?
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