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Biology 401, Spring 2018 Problem Set 2 6. A few amino acids are post-translationally removed from the C-terminal end of the beta- lactamase enzyme from B. imaginarium (i.e. - after it is translated and released from the ribosome, a protease chews off a few amino acids). The wild- type enzyme, which has had the amino acids removed from the C'-terminus, is 327 amino acids in length and the C-terminal amino acids are shown below aligned with the C-terminal amino acids of a frameshift mutant...

6) (10 pts) S glycolysis and gluconeogenesis. (a) First, consider a scheme that maximizes production of ribose-5-phosphate (R-5-P) via the PPP. Assume that flux through the PPP converts all the G-6-P to R-5-P. Under these conditions, what is the maximum possible yield of R-5-P and NADPH following the addition of 24 nmol of G-6-P to your extract? Show your work. uppose you have a liver cell extract that contains all the enzymes for the pentose phosphate pathway (PPP), Solution The ne...

According to the superposition principle, what percentage of the total current flowing through the 5 Ohm resistance in the circuit below from the 5V source? What percentage of the power supplied to the 5 Ohm is supplied by the 5V source? Solution Apply superposition: Case1 : when 5V source is present. Then Short circuit the 15 V source then Rnet = 10 + 5||10 = 13.33 ohms net current = 5/13.33 = 0.375 A current through 5 ohms = 10/(10+5) * 0.375 = 0.25 A Power = I^2 R =0.3...

7. You have isolated a protein (Boo) that binds to DNA in the region upstream of the promoter sequence of the Sys gene. If this protein is a positive regulator, which of the following could be true? a) Loss-of-function mutation in the gene encoding Boo would cause constitutive expression of Sys. b) Loss-of-function mutation in the gene encoding Boo would result in little or no expression of Sys. Solution As the protein induces gene expression, then it means it's expression will re...

A student finds out that he has overslept has only 30 min to reach his class to take a test. Which part of her autonomous system would get activated and how will it help her deal with the situation Explain.(3) Solution During stress sympathetic system gets activated, produces norepinephrin. Due to stress, flight or fight hormone gets produced. During a fight against stress, adrenal gland gets activated. Adrenal gland activity leads to increase in heart rate and energy levels get eleva...

are the most abundant heteropolysaccharides in the human body. They are highly (b) charged molecules and one from structure to form containing repeating disaccharide units of one (o They extend (e) peptide core in a ( which are linked by a specific tetrasaccharide units. Solution a)Glycosaminoglycans (GAGs)- long unbranched polysaccharides found mainly on cell surface or in the extracellular matrix (ECM) b)Negatively- which helps in take up of Ca2+, Na+, K+ etc. c) Amino sugar [eith...

24. Man, that is a ton of mussels on that rock bedl What type of competition describes an organism occupying space in attempt to outcompete others? a. Allelopathy b. Overgrowth c. Encounter Preemptive Solution Allelopathy is found in plants. It is a mechanism by which a plant hinders the growth of other plants by producing chemicals. Overgrowth is defined as uncontrolled growth of any organism or population. Encounter is referred as sudden exposure to any difficulty or face somethin...

17. About RNA transcription How does RNA transcription occur? How to regulate RNA transcription? How to make tissue-specific transcription for tissue-specific functions? Solution 17.Transcription is the first step of gene expression, in which a particular segment of DNA is copied into (especially mRNA) by the enzyme RNA polymerase. Both DNA and RNA are nucleic acids, which use base pairsof nucleotides as a complementary language. During transcription, a DNA sequence is read by an RNA...

8. (3.25 points) Mark the following statements as true (T) or false (F). If the statement is false, correct it to make it a true statement. Red blood cells are also known as leukocytes White blood cells with granules in their cytoplasm are known as agranulocytes The granulocytes include the neutrophils, eosinophils, and basophils -Erythrocytes carry oxygen through the body bound on hemoglobin, as deoxyhemoglobin Both monocytes and lymphocytes are granulocytes Platelets are whole cells invol...

                    "Organizational Development and Strategy" Please respond to the following:                  Solution Importance of Performance Management Process & Best Practices To Optimize Monitoring Performance Work Reviews/Feedback and Goal Management In today's workplace, performance improvement and the role of performance management is an increasingly popular topic. Why the intense focus on performance manageme...