NSG 552 Psychopharmacology Exam
3 Wilkes Qs and Ans with Explanation
1. What is the mechanism of action of Naloxone?
A) Pure opioid antagonist that competes and displaces opioids at
receptor sites.
Correct Answer A
Explanation: Naloxone competitively blocks opioid receptors, reversing
opioid effects.
2. What medications treat opioid disorder?
A) Methadone, Buprenorphine, Buprenorphine + Naloxone
Correct Answer A
Explanation: These medications are approved for opioid use disorder
treatment.
3. What medication for opioid use disorder is used with comorbid
pain?
A) Buprenorphine + Naloxone
Correct Answer A
Explanation: Buprenorphine combined with naloxone is used for opioid
disorder and can address pain.
,4. Inappropriate use of what substance may be due to uncontrolled
pain?
A) Opioids
Correct Answer A
Explanation: Uncontrolled pain often leads to misuse of opioids.
5. What are the Naltrexone delivery methods?
A) Tablet, Injectable, Implant
Correct Answer A
Explanation: Naltrexone is available in oral, injectable, and implant
forms.
6. What is one form of Naltrexone delivery method limited to
inpatient use?
A) Implant
Correct Answer A
Explanation: The implant form is generally used in inpatient or
controlled settings.
7. What is the mechanism of action of buprenorphine?
A) Mu receptor partial agonist for opioid withdrawal
Correct Answer A
, Explanation: Buprenorphine partially activates mu receptors, reducing
withdrawal symptoms.
8. What medication taken too soon after last opioid use increases the
chances of precipitated withdrawal?
A) Buprenorphine
Correct Answer A
Explanation: Buccal or sublingual buprenorphine can precipitate
withdrawal if given too early.
9. What are symptoms of opioid intoxication?
A) Nausea, respiratory depression, constipation, itching, miosis,
euphoria, sedation
Correct Answer A
Explanation: These are classic signs of opioid overdose.
10. What are withdrawal symptoms of opioids?
A) Nausea, vomiting, diarrhea, dehydration, irritability, restlessness,
yawning, twitching, increased HR and BP, chills, increased temperature,
rhinorrhea, lacrimation, dilated pupils
Correct Answer A
Explanation: These symptoms reflect opioid withdrawal.
3 Wilkes Qs and Ans with Explanation
1. What is the mechanism of action of Naloxone?
A) Pure opioid antagonist that competes and displaces opioids at
receptor sites.
Correct Answer A
Explanation: Naloxone competitively blocks opioid receptors, reversing
opioid effects.
2. What medications treat opioid disorder?
A) Methadone, Buprenorphine, Buprenorphine + Naloxone
Correct Answer A
Explanation: These medications are approved for opioid use disorder
treatment.
3. What medication for opioid use disorder is used with comorbid
pain?
A) Buprenorphine + Naloxone
Correct Answer A
Explanation: Buprenorphine combined with naloxone is used for opioid
disorder and can address pain.
,4. Inappropriate use of what substance may be due to uncontrolled
pain?
A) Opioids
Correct Answer A
Explanation: Uncontrolled pain often leads to misuse of opioids.
5. What are the Naltrexone delivery methods?
A) Tablet, Injectable, Implant
Correct Answer A
Explanation: Naltrexone is available in oral, injectable, and implant
forms.
6. What is one form of Naltrexone delivery method limited to
inpatient use?
A) Implant
Correct Answer A
Explanation: The implant form is generally used in inpatient or
controlled settings.
7. What is the mechanism of action of buprenorphine?
A) Mu receptor partial agonist for opioid withdrawal
Correct Answer A
, Explanation: Buprenorphine partially activates mu receptors, reducing
withdrawal symptoms.
8. What medication taken too soon after last opioid use increases the
chances of precipitated withdrawal?
A) Buprenorphine
Correct Answer A
Explanation: Buccal or sublingual buprenorphine can precipitate
withdrawal if given too early.
9. What are symptoms of opioid intoxication?
A) Nausea, respiratory depression, constipation, itching, miosis,
euphoria, sedation
Correct Answer A
Explanation: These are classic signs of opioid overdose.
10. What are withdrawal symptoms of opioids?
A) Nausea, vomiting, diarrhea, dehydration, irritability, restlessness,
yawning, twitching, increased HR and BP, chills, increased temperature,
rhinorrhea, lacrimation, dilated pupils
Correct Answer A
Explanation: These symptoms reflect opioid withdrawal.
