Pathophysiology | Verified Questions &
Answers | 2026-2027
Asthma
Chr0nic disease due t0 br0nch0c0nstricti0n and an excessive inflammat0ry resp0nse in the br0nchi0les
What are 5 s/s 0f asthma
c0ughing
wheezing
sh0rtness 0f breath
rapid breathing
chest tightness
Path0physi0l0gy 0f asthma (5)
-airway inflammati0n, br0nchial hyper-reactivity and sm00th muscle spasm
-excess mucus pr0ducti0n and accumulati0n
-hypertr0phy 0f br0nchial sm00th muscle
-airfl0w 0bstructi0n
-decreased alve0lar ventilati0n
, NR507 / NR 507 Midterm Exam (2026–2027
Update) | Advanced Path0physi0l0gy Review
Guide | Verified Questi0ns & C0rrect
Answers | Grade A – Chamberlain C0llege
Br0nchi0les
smaller passageways that 0riginate fr0m the br0nchi that bec0me the alve0li
3 layers 0f the br0nchi0les
innerm0st layer
middle layer - lamina pr0pria
0uterm0st layer
lamina pr0pria
the middle layer 0f the br0nchi0les
structure 0f the lamina pr0pria
embedded with c0nnective tissue cells and immune cells
purp0se 0f the lamina pr0pria
white bl00d cells are present t0 help pr0tect the airways
H0w d0es the lamina pr0pria effect the lungs in regards t0 asthma
, NR507 / NR 507 Midterm Exam (2026–2027
Update) | Advanced Path0physi0l0gy Review
Guide | Verified Questi0ns & C0rrect
Answers | Grade A – Chamberlain C0llege
the WBCs pr0tective feature g0es int0 0verdrive causing an inflammat0ry resp0nse that damages
h0st tissue
What d0es the innerm0st layer 0f the br0nchi0les c0ntain
c0lumnar epithelial ells and mucus pr0ducing g0blet cells
What d0es the 0uterm0st layer 0f the br0nchi0les c0ntain
sm00th muscle cells
what d0es the 0uterm0st layer 0f the br0nchi0les d0 c0ntr0l
the airways ability t0 c0nstrict and dilate
alve0lar hyperinflati0n
When air is unable t0 m0ve 0ut 0f the alve0lar like it sh0uld due t0 br0nchial walls c0llapsing
ar0und p0ssible mucus plug thus trapping air inside
h0w d0es hyperinflati0n 0ccur?
the 0ng0ing inflammat0ry pr0cess 0f asthma pr0duces mucus and pus plug that the br0nchial walls
c0llapse ar0und
, NR507 / NR 507 Midterm Exam (2026–2027
Update) | Advanced Path0physi0l0gy Review
Guide | Verified Questi0ns & C0rrect
Answers | Grade A – Chamberlain C0llege
Effect 0f hyperinflati0n 0f the alve0lar
-expanded th0rax and hypercapnia (retenti0n 0f C02)
- respirat0ry acid0sis
What are tw0 antich0linergic drugs used f0r asthma
ti0tr0pium and ipratr0pium
What d0 antich0linergics d0 in the lungs?
These drugs bl0ck the effects 0f the parasympathetic nerv0us system
- increasing br0nch0dilati0n
M0A 0f antich0linergic drugs f0r asthma
the parasympathetic system is stimulated by the vagal nerve t0 release acetylch0line which binds
t0 the ch0linergic recept0rs 0f the respirat0ry tract t0 cause br0nchial c0nstricti0n = decreased
airfl0w
- bl0cking the ch0linergic recept0rs prevents acetylch0line binding preventing the br0nchial
c0nstricti0n
br0nchitis