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Samenvatting HS4 erfelijkheidsleer

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Samenvatting HS4 (het menselijke genoom en onze genen) erfelijkheidsleer

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December 4, 2025
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2025/2026
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ERFELIJKHEIDSLEER
HOOFDSTUK 4 – HET MENSELIJKE GENOOM EN ONZE GENEN




DNA, de molecule van het leven




van Onbekende auteur is gelicentieerd onder


Het menselijke genoom
DNA in de celkern (nucleair genoom):

 23 paar chromosomen
- 22 paar autosomen
- 2 geslachtschromosomen
 Ongeveer 20.000 genen
 3 miljard bp of 6 miljard nucleotiden
 Exonen = coderende stukken DNA
 Intronen = niet coderende stukken DNA




DNA, drager van erfelijke informatie

1

,  DNA = deoxyribonucleïnezuur
 DNA = polymeer van nucleotiden
 Nucleotide = nuceleoside + fosfaatgroep
- Pentose suiker (5C) (deoxyribose)
- N-bevattende basen:
 Cytosine ( C) en thymine (T) = pyrimidines
 Adenine (A) en guanine (G) = purines
 Fosfaatgroep

De organische basen waaruit de nucleotiden zijn opgebouwd




van Onbekende auteur is gelicentieerd onder




De nucleotide waaruit het DNA is opgebouwd




Nucleotiden kunnen paren vormen via hun basen




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