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CBSE-STEP 1 SIMPLE MEMORIZATION QUESTIONS WITH CORRECT ANSWERS .

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CBSE-STEP 1 SIMPLE MEMORIZATION QUESTIONS WITH CORRECT ANSWERS .

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Written in
2025/2026
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CBSE/STEP 1 SIMPLE MEMORIZATION QUESTIONS
WITH CORRECT ANSWERS 2025-2026

Na - (Cl + HCO3) - CORRECT ANSWER -Anion gap equation



What decreases the affinity of histones for DNA? - CORRECT ANSWER -Histone
acetyltransferases



What is caused by CAG as a trinucleotide repeat on Ch4? - CORRECT ANSWER -Huntingtons



What is caused by CGG trinucleotide repeat on the X chromosome? - CORRECT ANSWER -Fragile
X



What is caused by CTG trinucleotide repeats on Ch19? - CORRECT ANSWER -Myotonic
Dystrophy I



What is caused by GAA trinucleotide repeat on Ch9? - CORRECT ANSWER -Friedreich Ataxia



What is caused by one -or- both maternal gene(s) silenced on Ch15? - CORRECT ANSWER -
Prader-Willi



What mutation is responsible for homologous recombination leading to prostate, ovarian
and/or breast cancer? - CORRECT ANSWER -BRCA-1



What repair is used to correct damage done to DNA when a nucleotide is missing from the
sugar-phophate backbone or when spontaneous deamination converts a cytosine residue to a
uracil residue? - CORRECT ANSWER -Base excision repair



How is DNA-helix distorting damage repaired? - CORRECT ANSWER -Nucleotide excision repair

, What removes acetyl groups from histones which decreases the transcription of genes because
nucleosome structure becomes more compact? - CORRECT ANSWER -Histone deacetylase



UAG, UAG and UGA are known as? - CORRECT ANSWER -Stop codons



Pituitary tumors, pancreatic endocrine tumors and parathyroid adenomas are found in? -
CORRECT ANSWER -MEN1



Anti-U1 RNP (ribonucleoprotein) is found in? - CORRECT ANSWER -Mixed connective tissue
disorder



Anti-Ro/SSA and/or Anti-La/SSB are found in? - CORRECT ANSWER -Sjogren's



Anti-phospholipase A2 receptor is found in? - CORRECT ANSWER -Primary membranous
nephropathy



Anti-glutamic acid decarboxylase and/or islet cell cytoplasmic ABs are found in? - CORRECT
ANSWER -DM1



Anti-hemidesmosome is found in? - CORRECT ANSWER -Bullous pemphigoid



Antisynthetase, Anti-Jo-1, Anti-SRP, Anti-Helicase and/or Anti-Mi-2 is found in? - CORRECT
ANSWER -Polymyositis

Dermatomyositis



Anti-presynaptic voltage-gated calcium channel found in? - CORRECT ANSWER -Lambert-Eaton
R236,45
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