NCLEX-RN Comprehensive Practice Exam
Full Testbank 2025-2026
1. A client is learning to use crutches for the first time. The nurse should include in the teaching
that improper use of crutches can lead to which complication?
A. Infiltration
B. Axillary nerve damage
C. Amyotrophic lateral sclerosis
D. Crushing syndrome
Correct Answer: B
Rationale: Improper use of crutches, where body weight is supported by the axillae instead of the
hands, can put excessive pressure on the axillary nerve, leading to nerve damage.
2. When assessing a client with suspected acute cholecystitis, the nurse anticipates which
finding?
A. Left lower quadrant pain
B. Projectile vomiting
C. Right upper quadrant pain radiating to the shoulder blades
D. Clay-colored stools
Correct Answer: C
Rationale: A key symptom of acute cholecystitis is nausea, vomiting, and right upper quadrant
abdominal pain that may radiate to the shoulder blades.
,3. A nurse is caring for a client with a confirmed diagnosis of epiglottitis. What is the nurse's
priority action?
A. Administer intravenous antibiotics.
B. Encourage oral fluid intake.
C. Protect the client's airway.
D. Obtain a throat culture.
Correct Answer: C
Rationale: Epiglottitis is a medical emergency where the priority is to protect the airway. This
includes helping the client sit up and lean forward, and avoiding actions that may cause agitation
or crying.
4. A client is diagnosed with ventricular fibrillation. What is the priority intervention for the
nurse?
A. Administer Amiodarone.
B. Initiate CPR and prepare for defibrillation.
C. Provide supplemental oxygen.
D. Obtain a 12-lead ECG.
Correct Answer: B
Rationale: Ventricular fibrillation is a deadly cardiac rhythm. The immediate, life-saving
interventions are CPR and defibrillation (d-fib).
,5. The nurse is preparing to administer a blood transfusion. Which solution should be used to
prime the intravenous tubing?
A. Lactated Ringer's
B. 5% Dextrose in Water
C. 0.9% Sodium Chloride
D. 0.45% Sodium Chloride
Correct Answer: C
Rationale: Normal saline (0.9% Sodium Chloride) is the only solution used for administering
blood transfusions, as it is compatible with blood products.
6. A client with Cushing syndrome is prescribed a new medication. Which class of over-the-
counter medication should the nurse advise the client to avoid?
A. Antacids
B. NSAIDs
C. Antihistamines
D. Laxatives
Correct Answer: B
Rationale: Clients with Cushing syndrome should avoid NSAIDs as they can increase the risk of
bleeding.
7. A client with hypovolemic shock would have which expected change in blood pressure?
A. A decrease in systolic pressure.
, B. A decrease in diastolic pressure.
C. An increase in diastolic pressure.
D. A widened pulse pressure.
Correct Answer: C
Rationale: In hypovolemic shock, the diastolic blood pressure increases. This is why vasodilators
are not given, as they would counteract this compensatory mechanism.
8. A postpartum client exhibits signs of hemorrhage. The nurse recalls that the "4 T's" of
postpartum hemorrhage include:
A. Thrombosis, Temperature, Trauma, Tone
B. Tissue, Thrombin, Trauma, Tone
C. Tachycardia, Tissue, Trauma, Thrombin
D. Tone, Tachycardia, Tissue, Temperature
Correct Answer: B
Rationale: The "4 T's" of postpartum hemorrhage are Tone (uterine atony), Tissue (retained
placenta), Trauma (lacerations), and Thrombin (coagulopathy).
9. A client taking Lisinopril should be monitored for which electrolyte imbalance?
A. Hyponatremia
B. Hypokalemia
C. Hyperkalemia
Full Testbank 2025-2026
1. A client is learning to use crutches for the first time. The nurse should include in the teaching
that improper use of crutches can lead to which complication?
A. Infiltration
B. Axillary nerve damage
C. Amyotrophic lateral sclerosis
D. Crushing syndrome
Correct Answer: B
Rationale: Improper use of crutches, where body weight is supported by the axillae instead of the
hands, can put excessive pressure on the axillary nerve, leading to nerve damage.
2. When assessing a client with suspected acute cholecystitis, the nurse anticipates which
finding?
A. Left lower quadrant pain
B. Projectile vomiting
C. Right upper quadrant pain radiating to the shoulder blades
D. Clay-colored stools
Correct Answer: C
Rationale: A key symptom of acute cholecystitis is nausea, vomiting, and right upper quadrant
abdominal pain that may radiate to the shoulder blades.
,3. A nurse is caring for a client with a confirmed diagnosis of epiglottitis. What is the nurse's
priority action?
A. Administer intravenous antibiotics.
B. Encourage oral fluid intake.
C. Protect the client's airway.
D. Obtain a throat culture.
Correct Answer: C
Rationale: Epiglottitis is a medical emergency where the priority is to protect the airway. This
includes helping the client sit up and lean forward, and avoiding actions that may cause agitation
or crying.
4. A client is diagnosed with ventricular fibrillation. What is the priority intervention for the
nurse?
A. Administer Amiodarone.
B. Initiate CPR and prepare for defibrillation.
C. Provide supplemental oxygen.
D. Obtain a 12-lead ECG.
Correct Answer: B
Rationale: Ventricular fibrillation is a deadly cardiac rhythm. The immediate, life-saving
interventions are CPR and defibrillation (d-fib).
,5. The nurse is preparing to administer a blood transfusion. Which solution should be used to
prime the intravenous tubing?
A. Lactated Ringer's
B. 5% Dextrose in Water
C. 0.9% Sodium Chloride
D. 0.45% Sodium Chloride
Correct Answer: C
Rationale: Normal saline (0.9% Sodium Chloride) is the only solution used for administering
blood transfusions, as it is compatible with blood products.
6. A client with Cushing syndrome is prescribed a new medication. Which class of over-the-
counter medication should the nurse advise the client to avoid?
A. Antacids
B. NSAIDs
C. Antihistamines
D. Laxatives
Correct Answer: B
Rationale: Clients with Cushing syndrome should avoid NSAIDs as they can increase the risk of
bleeding.
7. A client with hypovolemic shock would have which expected change in blood pressure?
A. A decrease in systolic pressure.
, B. A decrease in diastolic pressure.
C. An increase in diastolic pressure.
D. A widened pulse pressure.
Correct Answer: C
Rationale: In hypovolemic shock, the diastolic blood pressure increases. This is why vasodilators
are not given, as they would counteract this compensatory mechanism.
8. A postpartum client exhibits signs of hemorrhage. The nurse recalls that the "4 T's" of
postpartum hemorrhage include:
A. Thrombosis, Temperature, Trauma, Tone
B. Tissue, Thrombin, Trauma, Tone
C. Tachycardia, Tissue, Trauma, Thrombin
D. Tone, Tachycardia, Tissue, Temperature
Correct Answer: B
Rationale: The "4 T's" of postpartum hemorrhage are Tone (uterine atony), Tissue (retained
placenta), Trauma (lacerations), and Thrombin (coagulopathy).
9. A client taking Lisinopril should be monitored for which electrolyte imbalance?
A. Hyponatremia
B. Hypokalemia
C. Hyperkalemia
