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NURS 611 Exam 4 Study Guide 2025: Advanced Pathophysiology Practice

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Prepare for your NURS 611 Exam 4 in 2025. Get comprehensive review materials, practice questions, and key concepts for advanced pathophysiology and clinical applications for nurse practitioners.

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Exam 4: NURS611 / NURS 611 (Latest 2025 UPDATES

STUDY BUNDLE) Advanced Pathophysiology Exams |

Questions and Verified Answers | Graded A -

Maryville

Bones .....ANSWER.....provide support and production for the

body's tissues and organs.




Important source of minerals and blood cells

Bone formation .....ANSWER.....begins during embryonic

development with the differentiation of mesenchymal cells into

either chondrocytes or preosteoblasts.




bone minerals either crystalize on a cartilage or become bone

forming cells w/out cartilage

,Page 2 of 44


Bone tissue .....ANSWER.....continuously being resorbed and

synthesized by bone-remodeling units of osteoclasts and

osteoblasts

RANKL .....ANSWER.....Receptor activator of nuclear factor

kappa-B ligand




includes osteoclast activation and bone resorption

OPG .....ANSWER.....osteoprotegerin




protein. attachment serves as a decoy receptor for RANKL and

blocks osteoclast activity




decreases bone resorption.

RANKL and OPG balance .....ANSWER.....Quality of bone

,Page 3 of 44


Bone composition .....ANSWER.....compact and spongy bone

tissue.

compact bone .....ANSWER.....highly organized into haversian

systems that consist of concentric layers of crystallized matrix

surrounding a central canal that contains blood vessels and

nerves.

crystallized matrix in compact bone .....ANSWER.....has concentric

layers with small spaces containing osteocytes. Canaliculi inter

connect the osteocyte space.

crystallized matrix in spongy bone .....ANSWER.....arranged in

bars or plates. spaces containing osteocytes are dispersed

between the bars or plates and interconnected by canaliculi

BMPs (bone morphogenic proteins) .....ANSWER.....involved in

multiple crucial functions in the skeletal system

how many bones in the body .....ANSWER.....206

, Page 4 of 44




divided into axial skeleton and appendicular skeleton

Bone Classification .....ANSWER.....long, short, flat, irregular

long bones .....ANSWER.....longer than they are wide. broad end

called epiphysis, broad neck called metaphysis, and narrow

midportion called diaphysis that contains the medullar cavity.

Hematoma .....ANSWER.....formation provides the fibrin

framework for formation and organization of granulation tissues

granulation tissue .....ANSWER.....provides a cartilage model for

the formation and crystallization of bone matrix

Remodeling .....ANSWER.....restores the original shape and size

to injured bone

joint .....ANSWER.....site of attachment of 2 or more bones.




provide stability and mobility of the skeleton
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