,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 9th Edition Test Bank
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Table of contents:
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I. Principles Of Laboratory Medicine
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Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
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Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
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Chapter 3. Clinical Evaluation of Methods
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Chapter 4. Evidence-Based Laboratory Medicine
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Chapter 5. Establishment and Use of Reference Values
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Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
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Chapter 7. Quality Management
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II. Analytical Techniques And Instrumentation
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Chapter 8. Principles of Basic Techniques and Laboratory Safety
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Chapter 9. Optical Techniques
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Chapter 10. Electrochemistry and Chemical Sensors
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Chapter 11. Electrophoresis
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Chapter 12. Chromatography
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Chapter 13. Mass Spectrometry
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Chapter 14. Enzyme and Rate Analyses
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Chapter 15. Immunochemical Techniques
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Chapter 16 Automation mj mj
Chapter 17. Point-of-Care Instrumentation
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III. Analytes
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Chapter 18. Amino Acids, Peptides, and Proteins
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Chapter 19. Serum Enzymes
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Chapter 20. Tumor Markers and Cancer Genes
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Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
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Chapter 22. Carbohydrates
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Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
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Chapter 24. Electrolytes and Blood Gases
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Chapter 25. Hormones mj mj
Chapter 26. Catecholamines and Serotonin
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Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
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Chapter 28. Hemoglobin, Iron, and Bilirubin
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Chapter 29. Porphyrins and Porphyrias
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Chapter 30. Therapeutic Drugs and Their Management
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Chapter 31. Clinical Toxicology
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Chapter 32. Toxic Metals
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IV. Pathophysiology
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Chapter 33. Diabetes mj mj
,Chapter 34. Cardiovascular Disease
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Chapter 35. Kidney Disease
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Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
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Chapter 37. Liver Disease
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Chapter 38. Gastrointestinal and Pancreatic Diseases
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Chapter 39. Disorders of Bone and Mineral Metabolism
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Chapter 40. Disorders of the Pituitary Gland
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Chapter 41. Disorders of the Adrenal Cortex
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Chapter 42. Thyroid Disorders
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Chapter 43. Reproduction-Related Disorders
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Chapter 44. Pregnancy and Prenatal Testing
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Chapter 45. Newborn Screening and Inborn Errors of Metabolism
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Chapter 46. Pharmacogenetics
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V. Molecular Diagnostics
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Chapter 47. Principles of Molecular Biology
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Chapter 48. Nucleic Acid Techniques and Applications
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Chapter 49. Genomes and Nucleic Acid Alterations
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, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine TestB
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ank
MULTIPLE CHOICE mj
1. An individual working in a clinical chemistry laboratory is married to a sales representati
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ve who works for a company that sells chemistry laboratory supplies. When the laborator
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y manager requests a list of needed supplies, cost of supplies, and vendors, this individual
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only recommends the spouse’s company as the vendor. This is considered to be a(n):
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a. accounting issue. mj
b. possible conflict of interest. mj mj mj
c. maintenance of confidentiality issue. mj mj mj
d. problem with resource allocation. mj mj mj
ANS: B mj
Concern has been raised over the interrelationships between practitioners in the medical fiel
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d and commercial suppliers of drugs, devices, equipment, etc., to the medical profession.
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Similarly, relationships have been scrutinized between clinical laboratorians and manufactu
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rers and providers of diagnostic equipment and supplies. These concerns led the National I
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nstitutes of Health (NIH) in 1995 to require official institutional review of financial disclos
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ure by researchers and management of situations in which disclosure indicates potential con
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flicts of interest. mj mj
DIF: 1 REF: m j Page 4-5 mj OBJ: 6 | 7 mj mj mj
2. A patient visits her physician stating that her prescribed painkiller is not working to red
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uce the pain following her recent surgery. A friend of the patient claims that the same pa
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inkiller ―worked wonders‖ to reduce her pain after the same surgery. The physician stat
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es that the difference in the effect of the drug might be caused by
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, which is studied in pharmacog mj mj mj mj mj
enetics.
a. epidemiology
b. an inherited disease mj mj
c. a conflict of interest
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d. a genetic variation in drug-metabolizing enzymes
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ANS: D mj
Pharmacogenetics is the study of the genetic variation of drug metabolism between indivmj mj mj mj mj mj mj mj mj mj mj mj
iduals.
DIF: 1 REF: mjmj Page 3 mj OBJ: 1 mj
3. John works in a molecular diagnostics laboratory and receives a blood sample that has t
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he name of a close friend printed on the bar-
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coded label. The genetic test that is ordered on the friend’s sample would provide diagn
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ostic information about a disorder that has a poor prognosis, and the test is usually perf
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ormed by John. He asks a fellow employee to analyze the sample for him and not divul
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ge the results. This ethical issue concerns:
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a. confidentiality of patient genetic and medical information. mj mj mj mj mj mj
b. a conflict of interest.
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c. resource allocation. mj
d. diagnostic accuracy. mj
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Table of contents:
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I. Principles Of Laboratory Medicine
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Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
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Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
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Chapter 3. Clinical Evaluation of Methods
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Chapter 4. Evidence-Based Laboratory Medicine
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Chapter 5. Establishment and Use of Reference Values
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Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
mj mj mj mj mj mj mj mj
Chapter 7. Quality Management
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II. Analytical Techniques And Instrumentation
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Chapter 8. Principles of Basic Techniques and Laboratory Safety
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Chapter 9. Optical Techniques
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Chapter 10. Electrochemistry and Chemical Sensors
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Chapter 11. Electrophoresis
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Chapter 12. Chromatography
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Chapter 13. Mass Spectrometry
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Chapter 14. Enzyme and Rate Analyses
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Chapter 15. Immunochemical Techniques
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Chapter 16 Automation mj mj
Chapter 17. Point-of-Care Instrumentation
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III. Analytes
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Chapter 18. Amino Acids, Peptides, and Proteins
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Chapter 19. Serum Enzymes
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Chapter 20. Tumor Markers and Cancer Genes
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Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
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Chapter 22. Carbohydrates
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Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
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Chapter 24. Electrolytes and Blood Gases
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Chapter 25. Hormones mj mj
Chapter 26. Catecholamines and Serotonin
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Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
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Chapter 28. Hemoglobin, Iron, and Bilirubin
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Chapter 29. Porphyrins and Porphyrias
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Chapter 30. Therapeutic Drugs and Their Management
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Chapter 31. Clinical Toxicology
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Chapter 32. Toxic Metals
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IV. Pathophysiology
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Chapter 33. Diabetes mj mj
,Chapter 34. Cardiovascular Disease
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Chapter 35. Kidney Disease
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Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
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Chapter 37. Liver Disease
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Chapter 38. Gastrointestinal and Pancreatic Diseases
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Chapter 39. Disorders of Bone and Mineral Metabolism
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Chapter 40. Disorders of the Pituitary Gland
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Chapter 41. Disorders of the Adrenal Cortex
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Chapter 42. Thyroid Disorders
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Chapter 43. Reproduction-Related Disorders
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Chapter 44. Pregnancy and Prenatal Testing
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Chapter 45. Newborn Screening and Inborn Errors of Metabolism
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Chapter 46. Pharmacogenetics
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V. Molecular Diagnostics
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Chapter 47. Principles of Molecular Biology
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Chapter 48. Nucleic Acid Techniques and Applications
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Chapter 49. Genomes and Nucleic Acid Alterations
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, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine TestB
mj mj mj mj mj mj mj mj mj
ank
MULTIPLE CHOICE mj
1. An individual working in a clinical chemistry laboratory is married to a sales representati
mj mj mj mj mj mj mj mj mj mj mj mj mj
ve who works for a company that sells chemistry laboratory supplies. When the laborator
mj mj mj mj mj mj mj mj mj mj mj mj mj
y manager requests a list of needed supplies, cost of supplies, and vendors, this individual
mj mj mj mj mj mj mj mj mj mj mj mj mj mj
only recommends the spouse’s company as the vendor. This is considered to be a(n):
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a. accounting issue. mj
b. possible conflict of interest. mj mj mj
c. maintenance of confidentiality issue. mj mj mj
d. problem with resource allocation. mj mj mj
ANS: B mj
Concern has been raised over the interrelationships between practitioners in the medical fiel
mj mj mj mj mj mj mj mj mj mj mj mj
d and commercial suppliers of drugs, devices, equipment, etc., to the medical profession.
mj mj mj mj mj mj mj mj mj mj mj mj
Similarly, relationships have been scrutinized between clinical laboratorians and manufactu
mj mj mj mj mj mj mj mj mj
rers and providers of diagnostic equipment and supplies. These concerns led the National I
mj mj mj mj mj mj mj mj mj mj mj mj mj
nstitutes of Health (NIH) in 1995 to require official institutional review of financial disclos
mj mj mj mj mj mj mj mj mj mj mj mj mj
ure by researchers and management of situations in which disclosure indicates potential con
mj mj mj mj mj mj mj mj mj mj mj mj
flicts of interest. mj mj
DIF: 1 REF: m j Page 4-5 mj OBJ: 6 | 7 mj mj mj
2. A patient visits her physician stating that her prescribed painkiller is not working to red
mj mj mj mj mj mj mj mj mj mj mj mj mj mj
uce the pain following her recent surgery. A friend of the patient claims that the same pa
mj mj mj mj mj mj mj mj mj mj mj mj mj mj mj mj
inkiller ―worked wonders‖ to reduce her pain after the same surgery. The physician stat
mj mj mj mj mj mj mj mj mj mj mj mj mj
es that the difference in the effect of the drug might be caused by
mj mj mj mj mj mj mj mj mj mj mj mj mj
, which is studied in pharmacog mj mj mj mj mj
enetics.
a. epidemiology
b. an inherited disease mj mj
c. a conflict of interest
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d. a genetic variation in drug-metabolizing enzymes
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ANS: D mj
Pharmacogenetics is the study of the genetic variation of drug metabolism between indivmj mj mj mj mj mj mj mj mj mj mj mj
iduals.
DIF: 1 REF: mjmj Page 3 mj OBJ: 1 mj
3. John works in a molecular diagnostics laboratory and receives a blood sample that has t
mj mj mj mj mj mj mj mj mj mj mj mj mj mj
he name of a close friend printed on the bar-
mj mj mj mj mj mj mj mj mj
coded label. The genetic test that is ordered on the friend’s sample would provide diagn
mj mj mj mj mj mj mj mj mj mj mj mj mj mj
ostic information about a disorder that has a poor prognosis, and the test is usually perf
mj mj mj mj mj mj mj mj mj mj mj mj mj mj mj
ormed by John. He asks a fellow employee to analyze the sample for him and not divul
mj mj mj mj mj mj mj mj mj mj mj mj mj mj mj mj
ge the results. This ethical issue concerns:
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a. confidentiality of patient genetic and medical information. mj mj mj mj mj mj
b. a conflict of interest.
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c. resource allocation. mj
d. diagnostic accuracy. mj
