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ATI - MUSCULOSKELETAL EXAM BRAND NEW ACTUAL EXAM WITH ANSWERS.

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When administering medications to the patient with gout, the nurse would recognize which of the following as a treatment for chronic disease? a. Colchicine b. Febuxostat c. Sulfasalazine d. Cyclosporine - correct answer -Correct answer: B Rationale: Febuxostat (Uloric), a selective inhibitor of xanthine oxidase, is given for long-term management of hyperuricemia in persons with chronic gout. Acute gouty arthritis is treated with colchicine and nonsteroidal antiinflammatory drugs (NSAIDs). In teaching a patient with SLE about the disorder, the nurse knows that the pathophysiology of SLE includes? a. circulating immune complexes formed from IgG autoantibodies reacting with IgG P a g e | 2 b. an autoimmune T-cell reaction that results in destruction of the deep dermal skin layer c. immunologic dysfunction leading to chronic inflammation in the cartilage and muscles d. the production of a variety of autoantibodies directed against components of the cell nucleus - correct answer -Correct answer: D Rationale: Systemic lupus erythematosus (SLE) is characterized by the production of many autoantibodies against nucleic acids (e.g., single-and double-stranded DNA), erythrocytes, coagulation proteins, lymphocytes, platelets, and many other self-proteins. Autoimmune reactions characteristically are directed against constituents of the cell nucleus (e.g., antinuclear antibodies [ANAs]), particularly DNA. Circulating immune complexes containing antibody against DNA are deposited in the basement membranes of capillaries in the kidneys, heart, skin, brain, and joints. Complement is activated, and inflammation occurs. The overaggressive antibody response is also related to activation of B and T cells. The specific manifestations of SLE depend on which cell types or organs are involved. SLE is a type III hypersensitivity response. The nurse is working with a 73-year-old patient with osteoarthritis (OA). In assessing the patient's understanding of this disorder, the nurse concludes teaching has been effective when the patient describes the condition as which of the following? A. Joint destruction caused by an autoimmune process P a g e | 3 B. Degeneration of articular cartilage in synovial joints C. Overproduction of synovial fluid resulting in joint destruction D. Breakdown of tissue in non-weight-bearing joints by enzymes - correct answer -Correct answer: B. Degeneration of articular cartilage in synovial joints Rationale: OA is a degeneration or breakdown of the articular cartilage in synovial joints. The condition has also been referred to as degenerative joint disease. The nurse is admitting a patient who is scheduled for knee arthroscopy related to osteoarthritis (OA). Which of the following findings would the nurse expect to be present on examination of the patient's knees? A. Ulnar drift B. Pain with joint movement C. Reddened, swollen affected joints D. Stiffness that increases with movement - correct answer -Correct answer: B. Pain with joint movement Rationale: OA is characterized predominantly by joint pain upon movement and is a classic feature of the disease. A 60-year-old woman has pain on motion in her fingers and asks the nurse whether this is just a result of aging. The best response by the nurse includes the information that? P a g e | 4 a. joint pain with functional limitation is a normal change that affects all people to some extent b. joint pain that develops with age is usually related to previous trauma or infection of the joints c. this is a symptom of a systemic arthritis that eventually affects all joints as the disease progresses d. changes in the cartilage and bones of joints may cause symptoms of pain and loss of function in some people as they age - correct answer -D. changes in the cartilage and bones of joints may cause symptoms of pain and loss of function in some people as they age. A patient with OA uses NSAIDs to decrease pain and inflammation. The nurse teaches the patient that common side effects of these drugs include? a. allergic reactions, fever, and oral lesions b. fluid retention, hypertension, and bruising c. skin rashes, gastric irritation, and headache d. prolonged bleeding time, blood dyscrasias, and hepatic damage - correct answer -C. skin rashes, gastric irritation, and headacche

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ATI MUSCULOSKELETAL
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Uploaded on
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Written in
2025/2026
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Page | 1

ATI - MUSCULOSKELETAL EXAM
BRAND NEW ACTUAL EXAM WITH
ANSWERS.


When administering medications to the patient with gout, the
nurse would recognize which of the following as a treatment for
chronic disease?


a. Colchicine
b. Febuxostat
c. Sulfasalazine
d. Cyclosporine - correct answer -Correct answer: B
Rationale: Febuxostat (Uloric), a selective inhibitor of xanthine
oxidase, is given for long-term management of hyperuricemia in
persons with chronic gout. Acute gouty arthritis is treated with
colchicine and nonsteroidal antiinflammatory drugs (NSAIDs).




In teaching a patient with SLE about the disorder, the nurse
knows that the pathophysiology of SLE includes?


a. circulating immune complexes formed from IgG autoantibodies
reacting with IgG

, Page | 2

b. an autoimmune T-cell reaction that results in destruction of the
deep dermal skin layer
c. immunologic dysfunction leading to chronic inflammation in the
cartilage and muscles
d. the production of a variety of autoantibodies directed against
components of the cell nucleus - correct answer -Correct answer:
D
Rationale: Systemic lupus erythematosus (SLE) is characterized
by the production of many autoantibodies against nucleic acids
(e.g., single-and double-stranded DNA), erythrocytes, coagulation
proteins, lymphocytes, platelets, and many other self-proteins.
Autoimmune reactions characteristically are directed against
constituents of the cell nucleus (e.g., antinuclear antibodies
[ANAs]), particularly DNA. Circulating immune complexes
containing antibody against DNA are deposited in the basement
membranes of capillaries in the kidneys, heart, skin, brain, and
joints. Complement is activated, and inflammation occurs. The
overaggressive antibody response is also related to activation of
B and T cells. The specific manifestations of SLE depend on
which cell types or organs are involved. SLE is a type III
hypersensitivity response.




The nurse is working with a 73-year-old patient with osteoarthritis
(OA). In assessing the patient's understanding of this disorder,
the nurse concludes teaching has been effective when the patient
describes the condition as which of the following?


A. Joint destruction caused by an autoimmune process

, Page | 3

B. Degeneration of articular cartilage in synovial joints
C. Overproduction of synovial fluid resulting in joint destruction
D. Breakdown of tissue in non-weight-bearing joints by enzymes -
correct answer -Correct answer: B. Degeneration of articular
cartilage in synovial joints Rationale: OA is a degeneration or
breakdown of the articular cartilage in synovial joints. The
condition has also been referred to as degenerative joint disease.




The nurse is admitting a patient who is scheduled for knee
arthroscopy related to osteoarthritis (OA). Which of the following
findings would the nurse expect to be present on examination of
the patient's knees?


A. Ulnar drift
B. Pain with joint movement
C. Reddened, swollen affected joints D. Stiffness that increases
with movement - correct answer -Correct answer: B. Pain with
joint movement Rationale: OA is characterized predominantly by
joint pain upon movement and is a classic feature of the disease.




A 60-year-old woman has pain on motion in her fingers and asks
the nurse whether this is just a result of aging. The best response
by the nurse includes the information that?

, Page | 4

a. joint pain with functional limitation is a normal change that
affects all people to some extent
b. joint pain that develops with age is usually related to previous
trauma or infection of the joints
c. this is a symptom of a systemic arthritis that eventually affects
all joints as the disease progresses
d. changes in the cartilage and bones of joints may cause
symptoms of pain and loss of function in some people as they age
- correct answer -D. changes in the cartilage and bones of joints
may cause symptoms of pain and loss of function in some people
as they age.




A patient with OA uses NSAIDs to decrease pain and
inflammation. The nurse teaches the patient that common side
effects of these drugs include?


a. allergic reactions, fever, and oral lesions
b. fluid retention, hypertension, and bruising
c. skin rashes, gastric irritation, and headache
d. prolonged bleeding time, blood dyscrasias, and hepatic
damage - correct answer -C. skin rashes, gastric irritation, and
headacche

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